What is Dasiglucagon?
The treatment for severe hypoglycemia in adults and children older than 6 years is dasiglucagon. This medication guide does not list all possible uses of dasiglucagon.
Side effects of Dasiglucagon
If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: hives, feeling lightheaded, difficulty breathing, a fast or slower heartbeat, or swelling of your lips, face, tongue, or throat.
Dasiglucagon may cause serious side effects. If you experience:
- If you experience a severe headache or blurred vision, feel a pounding in the neck or ears, or if your vision is blurred, it could be a sign of a serious headache.
- Low blood sugar, whether new or continuing, can cause headaches, nausea, sweating, irritability, and dizziness.
Dasiglucagon can cause the following side effects:
- Nausea, vomiting, diarrhea;
- Headache;
- Pain where an injection is given.
There may be other side effects. Call your physician if experiencing symptoms. You can contact the FDA at 1-800-FDA-1088 if experiencing side effects and wish to report them.
Similar/related drugs
Glucagon, Baqsimi, Diazoxide, Gvoke, Zegalogue, and GlucaGen
Warnings
Before you use it, make sure that you and any caregivers you have are familiar with how to administer dasiglucagon. The hypoglycemia must be treated as soon as possible.Low blood sugar can result in seizures, coma or even death.
Before you take this drug
If you have an allergy to dasiglucagon or:
- A tumor of the pancreas (insuloma);
- A tumor of the adrenal cortex (pheochromocytoma)
Tell your doctor if:
- Any tumor of the pancreas
- Low blood sugar is a chronic condition.
- Adrenal gland disorders
- A latex allergy,
- If you haven't eaten regularly in the past,
Don't give dasiglucagon without consulting a doctor. Inform your doctor if you are pregnant or nursing. Dasiglucagon should not harm a baby in utero, but treating hypoglycemia quickly would be more important than any potential risks.Under certain conditions, informing caregivers that you are breastfeeding or pregnant might not always be possible in an emergency situation.Be sure to tell any doctor who is caring for you or your baby that you've taken this medication.
How to take Dasiglucagon?
As soon as hypoglycemia is detected, it should be treated.Low blood sugar can result in seizures, coma or even death. Dasiglucagon can be injected into the skin. You will learn how to administer emergency dasiglucagon for severe hypoglycemia. After each dasiglucagon shot, call your doctor. Please carefully read and heed any directions included with your medication. If there are any discrepancies between what the instructions say and your own understanding, consult your healthcare provider or pharmacist immediately for clarification. Don't make an injection until it is time for administration, especially if its color has changed or contains particles; new medications should be referred directly to a pharmacist for advice and approval. Prior to using dasiglucagon, make sure that both you and your caregivers understand its usage and administration. Children as well as adults require equal doses; be sure to follow any directions from your healthcare provider regarding dosing schedules or dosage amounts.
After the injection, you should consume a source of sugar that acts quickly (fruit juices, glucose, hard candies, raisins, or non-diet soft drinks) and a small snack or meal, such as peanut butter or cheese and crackers. Get emergency medical attention if the patient doesn't improve in 15 minutes. You may need to administer a second dasiglucagon shot. Stress, illness, surgery, or alcohol consumption can affect blood sugar levels. Consult with your physician prior to altering either the dose or schedule of any of your medication. Follow your diet, medications, and exercise regimens closely to avoid severe hypoglycemia. Keep away from cooling elements. Do not freeze. Dasiglucagon can be stored at room temperature, but it must be used within 12 months. Store the medicine in its protective case to protect it from light. After storing the medicine at room temperature, do not return it to the refrigerator. The expiration date is on the label.
Details on dosage
Adult dose for hypoglycemia:
Subcutaneously, inject 0.6 mg into the lower abdomen, buttocks, or outer upper arm.
If no response is seen after 15 minutes, you may administer a second dose of 0.6 mg.
Comments:
Patients and caregivers must be familiar with the instructions; the drug should be given as soon as possible if severe hypoglycemia has been recognized.
Call for immediate assistance after administration.
Once the patient responds to treatment, oral carbohydrate should be administered to replenish liver glycogen.
Use: To treat severe hypoglycemia among patients with diabetes.
The usual pediatric dose for hypoglycemia is
6 years and older: 0.6mg subcutaneously, once in the lower abdomen, buttocks, or outer upper arm
If no response is seen after 15 minutes, you may administer a second dose of 0.6 mg.
Comments:
Patients and caregivers must be familiar with the instructions; the drug should be given as soon as possible if severe hypoglycemia has been recognized.
Call for immediate assistance after administration.
Once the patient responds to treatment, oral carbohydrate should be administered to replenish liver glycogen.
Use: To treat severe hypoglycemia among pediatric patients with diabetes aged 6 years and older.
What happens if I miss the dose?
Dasiglucagon does not require a daily dosage schedule because it is only used when needed. If symptoms persist after using dasiglucagon, call your doctor immediately.
What happens if I overdose?
Call 1-800-222-1222 for poison help or seek immediate medical attention. Overdose symptoms include nausea, vomiting, and rapid heartbeats.
What should be avoided?
If your doctor prescribes any restrictions regarding food, beverage, or activity, follow their instructions.
Interaction with other drug
Tell your doctor about your other medications, including:
- Indomethacin;
- warfarin (coumadin, jantoven).
This list is incomplete. Dasiglucagon can be affected by other drugs, such as vitamins and herbs. This list does not include all possible drug interactions.
