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Cyanocobalamin (nasal)

Generic name: cyanocobalamin (nasal) [sye-AN-oh-koe-BAL-a-min]
Name of the brand: Nascobal
Dosage form: nasal spray (500 mcg/0.1 mL)
Drug class: vitamins

What is Cyanocobalamin?

Cyanocobalamin nasal (for use in the nasal passages) can be used for treating vitamin B12 deficiencies in patients suffering from severe anemia as well as other disorders. Cyanocobalamin nasal injections are usually administered in conjunction with an injection version of cyanocobalamin. Cyanocobalamin nasal could also be used to treat conditions that are not mentioned in this guide.

Side effects of Cyanocobalamin nasal

Contact a medical professional immediately in the event that you exhibit symptoms that indicate an allergy, such as symptoms of hives, breathing difficulties, and swelling of your lips, face, and tongue.

Get your doctor's attention immediately. If you suffer from:

  • Easily bruising or bleeding that is unusual, such as areas of red or purple on the skin
  • Lower potassium level; leg cramps constipation irregular heartbeats, chest flutters, and increased thirst or urination Tingling or numbness, muscles becoming weak, or a limp sensation

Common adverse effects of cyanocobalamin could include:

  • Nasal congestion;
  • Cold and influenza symptoms, such as nasal stuffiness, sore throat, and sinus pain
  • Headache;
  • Feeling tingling in your hands or feet;
  • Weakness;
  • Nausea; or
  • The tongue is swelling.

This is not a comprehensive list of all side effects. Others could happen. Contact your doctor for advice regarding medical effects. You can report symptoms to the FDA at 1-800-FDA-1088.

Similar or related drugs

cyanocobalamin, Vitamin B12, hydroxocobalamin, Dodex, and Neuroforte-R


Cytocobalamin should not be used when you have an allergy to cobalt or you suffer from the disease Leber's.

Prior to use this drug

This medicine is for you if you're allergic to cobalt or cyanocobalamin or if you suffer from Leber's disease (a genetic form of vision loss). Cyanocobalamin may cause the optic nerve to be damaged (and perhaps blindness) for people suffering from Leber's disease.

Inform your doctor if you have ever suffered from:

  • eye issues, Leber's disease (in the case of you as well as a member of your family),
  • A deficiency in iron, or folic acid deficiencies.

Inform your doctor if you are breastfeeding or pregnant. Your dosage needs could differ during pregnancy or during the time you breastfeed babies.

Cyanocobalamin nasal has not been recommended for use by anyone who is younger than

How to take Cyanocobalamin?

Cyanocobalamin nasal medication is typically given every week. Follow the directions on the label of your prescription and also read the medication guide or instructions sheets. Follow the medication precisely as directed.

Be sure to read and adhere to any instructions for use that come with your medication. Consult your physician or pharmacist for clarification if you are unsure of the instructions.

It is possible to have blood testing every 3 to 6 months, and your physician may alter your dosage based on the results.

Your dose needs may change if you become pregnant, if you breast-feed, or if you eat a vegetarian diet. Inform your doctor of any changes to your food habits or your medical conditions.

Inform your doctor if you suffer from sinus congestion. Cyclocobalamin might not work in the same way if you suffer from an irritable nose.

If you suffer from pernicious anemia, you may need to take cyanocobalamin daily throughout your life. Don't stop taking the medication unless your physician recommends it. If not treated, vitamin B12 deficiency could result in anemia or irreparable nerve damage.

Pernicious anemia can also be treated by using folic acid to ensure the maintenance of the red blood cell count. Folic acid on its own will not help treat vitamin B12 deficiency or prevent any injury to the spinal cord. Follow the directions for all medications.

Keep the container upright at room temperature. Keep away from sunlight and avoid freezing.

Details on dosage

Usual Adult Dose for Pernicious Anemia:

First dose: 100 mg intramuscularly, or deep subcutaneously, every day for up to 7 days.
If improvement in the clinical outcome is observed, an increase in reticulocytes is observed following the doses above:
100 mg once a day for seven doses, then:
100 mcg every 3 or every 4 days, for 2 to 3 months, and then:
Maintenance dose: 100–1000 mcg per month
Time of therapy: life

Inject folic acid in conjunction in the event of need.
The treatment must be performed using an oral medication in patients who have normal absorption of the intestinal tract.

Usual Adult Dose for B12 Nutritional Deficiency:

Between 25 and 2000 mg every day

Usual Adult Dose for the Schilling Test:

1000 mg intramuscularly is the dose for flushing.

Usual Pediatric Dose for B12 Nutritional Deficiency:

0.5 to 3 mcg per day

What happens if I miss the dose?

Take the medication as quickly as you can; however, do not miss any missed doses if you are nearing the time to take the next dose. Don't take two doses in one go.

What happens if I overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

What should be avoided?

Don't drink hot liquids or eat hot food for 1 hour prior to or one hour after using cyanocobalamin nasal.

Interaction with other drugs

Other drugs can also influence cyanocobalamin nasal function, such as prescription and over-the-counter medicines, vitamins, and herbal products. Discuss with your doctor all the medications you currently use and any medication you begin or stop taking.