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Plasminogen (human)

Genric Name: the plasminogen (human)
Brand name: Ryplazim
Form of dosage: intravenous powder for injection (tvmh 68.8 mg)
The class of drugs: miscellaneous uncategorized agents

What is Plasminogen (human)?

Plasminogen (human) can help elevate levels of plasminogen for those diagnosed with hypoplasminogenemia due to deficiency of type 1. Plasminogen (human) can be used for other purposes that are not mentioned in this guide.

Side effects of Plasminogen (human) 

See a doctor immediately. If you are experiencing

warning signs of an allergic response, such as symptoms of hives, difficulty breathing, and swelling of your lips, face, and tongue,

Get medical attention immediately. If you experience bloody or tarry stools, bleeding from your bowels, or bleeding that is heavy and doesn't stop after 30 minutes of continuous pressure.

Plasminogen may cause serious side effects. Consult your physician right away. If you suffer from:

  • difficulties with breathing; coughing;

  • the speech of your child; or

  • pelvic area, groin stomach, back discomfort in the back, pelvic area, stomach, or stomach.

Common negative effects of plasminogen could include:

  • stomach pain, nausea, constipation, bloating;

  • joint pain, back pain, and discomfort in your hands or feet;

  • tiredness;

  • dizziness;

  • headache;

  • Dry mouth or

  • bleeding.

This is not a comprehensive list of all side effects. Other side effects could occur. Consult your physician to seek medical advice on adverse effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.


Only use it according to the directions. Inform your doctor if you are taking other medications or suffer from any other medical condition or allergies.

Before you start taking this medicine

It is not recommended to make use of the plasminogen (human) in case you have an allergy to it.

Speak to your doctor if you have ever suffered from:

  • Issues with bleeding.

Plasminogen is produced from plasma from humans (parts of the blood) that could contain viruses that can cause illness. Discuss with your physician the potential risks and advantages of plasminogen.

How to take plasminogen Humans?

Follow the directions on the prescription label and review all medication guides and instructions sheets. Follow the medication precisely as directed.

Plasminogen (human) is introduced slowly into veins via an IV for the course of 10–30 minutes. You can receive this medicine in a medical setting at home, from a caretaker, or by injecting the drug yourself. The doctor will explain to you how often you should use this medication and how much to take each time.

Your blood could require frequent testing. Conserve the plasminogen (human) vials at ambient temperature or in the refrigerator. Don't keep them in the freezer. Other supplies can be stored at the temperature of the room. 

Do I be concerned if I miss a dose?

Consult your physician for instructions when you have missed a dose.

What will happen if I take excessively?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

What should be avoided?

Follow the instructions of your physician regarding any limitations on foods, drinks, or any activity. 

Interaction with other drugs

Other medications can influence the plasminogen (human). This includes medications that are prescribed and available over the counter, vitamins, and herbal products. Discuss with your doctor all the other medicines you take.