What is Cenobamate?
Cenobamate can be used to treat adults with partial-onset seizures. Cenobamate can be used in other ways not mentioned in this guide.
Side effects of Cenobamate
If you experience any of the following signs and symptoms of an allergic reaction: hives, difficulty breathing, swelling in lips, face, tongue or throat and difficulty swallowing Should a severe drug reaction arise, seek medical assistance immediately. You should tell your doctor if any symptoms worsen or change, including changes in mood or behaviour, anxiety, panic attacks, or trouble sleeping. Also, you may feel more impulsive, agitated, hostile, aggressive, or restless.
Cenobamate may cause serious allergies, which can have a life-threatening effect on your liver, blood, or other body parts. If you experience symptoms like these, call your doctor immediately or seek emergency medical attention.
- If you feel dizzy or faint, your heart may be pounding.
- Feeling very tired or weak
- Severe muscle pain;
- Sore throat, fever, swelling of the glands
- You may experience painful sores around the eyes or in your mouth
- You may experience swelling in your mouth, face, or throat.
- Trouble swallowing or breathing;
- Hives or a rash
- Yellowing of the skin or eyes
- Any illness or infection that doesn't improve
- Dizziness, difficulty walking, loss of coordination, vision issues, sleepiness or fatigue, and problems with memory or thinking are all symptoms of nervous system disorders.
Some of the common side effects associated with cenobamate include:
- Feeling tired
- Dizziness, drowsiness;
- Double vision
- Headache.
There may be other side effects. Call your physician if experiencing side effects; alternatively, the FDA can be reached at 1-800-FDA-1088 if wishing to report such.
Similar/related drugs
Sympazan, Briviact, Topiramate, Diazepam, Levetiracetam, Keppra, and Depakote
Warnings
Cenobamate may cause severe or life-threatening reactions in your liver, blood, or other body parts. If you experience symptoms like severe muscle pain or weakness, a high fever, swollen or swollen-looking glands, unusual bleeding or bruising, swelling of the face or throat, trouble breathing, hives, a rash or yellowing skin or eyes, or any illness that does not improve, call your doctor. Cenobamate can cause suicidal thoughts in some people. Be vigilant of any shift in your mood or symptoms that you encounter, or if they worsen. Intimate your physician immediately if these arise or develop new. Cenobamate should not be stopped abruptly. Do not stop using cenobamate suddenly.
Before you take this drug
Cenobamate should not be used if:
- A genetic heart rhythm disorder known as short-QT syndrome
Inform your physician of any of the following issues:
- Depression, or a mental disorder.
- Suicidal thoughts and actions
- Liver or kidney disease
- A blood cell disorder;
- An allergic reaction to medicine that causes a rash or affects your blood cells or internal organs
Cenobamate may lead to thoughts of suicide in some individuals. You will be required to visit your doctor regularly in order to monitor your progress. You or your family members should be aware of any changes in mood or symptoms. Don't start or stop seizure medications during pregnancy without consulting your doctor. A seizure could be harmful to both mother and child.As soon as you become pregnant, inform your physician immediately.
Cenobamate may make birth-control pills ineffective. Ask your doctor if you can use a non-oral contraceptive. These include injections, patches, rings for vaginal use, diaphragms, cervical caps, and contraceptive sponges. You may find your name on a registry if you are expecting to monitor the effects of cenobamate. Cenobamate may cause problems if breast-feeding is done.Consult a medical expert if any risks or worries are troubling you. Cenobamate cannot be used by anyone under the age of 18.
How to take cenobamate?
Read all the instructions or guides that come with your medication and follow the directions. Sometimes, your doctor will change the dose. You must take the medication exactly as prescribed. Cenobamate may be taken either with or without food. Do not crush, chew, or break the tablet. The tablet should not be crushed, chewed, or broken. Cenobamate should not be stopped suddenly, even when you are feeling fine. Sudden stopping may lead to increased seizures or unpleasant symptoms of withdrawal.Follow your doctor's recommendations when it comes to decreasing your dosage. Store away from heat and moisture at room temperature.
Details on dosage
Usual Adult Dose for Seizures:
Initial dose: oral 12.5 mg once daily for the first two weeks
Titration: 100 mg orally one time a week for weeks 7 and 8, 150 mg once daily for weeks 9 and 10.
Maintenance Dose: 200 mg once daily, starting at week 11.
Maximum Dose: 400 mg taken orally, once per day.
Comments:
This drug can be used either as monotherapy or as adjunctive therapy.
The potential for adverse reactions is high, so it's important to not exceed the dosage and titration.
The dose increase above the maintenance dose is based on the clinical response and tolerance.
Use: To treat partial-onset seizures.
What happens if I miss the dose?
If you miss a dosage, call your doctor to get instructions.
What happens if I overdose?
Reach out immediately if a poison occurs by calling 1-800-222-1222 for support, or seeking immediate medical care.
What should be avoided?
Cenobamate can cause blurred vision or affect your reaction. Do not drive or engage in any hazardous activities until you have determined how the medication will affect you. Alcohol consumption can have side effects when taken with this medication.
Interaction with other drug
Inform your doctor of all other medications you are taking to treat seizures. Cenobamate can make you feel drowsy or dizzy. Before taking an opioid, sleeping pill, muscle relaxant, or anxiety medicine, consult your doctor. Sometimes taking medications together may not be safe. Some drugs may affect the blood levels of drugs that you are taking, which can increase side effects and make them less effective. Cenobamate can be affected by other drugs, such as prescription and over-the-counter medicines, vitamins, and herbal products. Inform your doctor of all the medicines you are taking and those that you stop or start using.
