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Generic name: Capsaicin topical [kap-SAY-sin-TOP-i-kal]
Brand names include: Aspercreme Warming The Pain Relief Patch: Capzasin Back and Body, Capzasin-HP, Capzasin P, Castiva Warming,… Show the 17 brands.
Classification of drugs: Miscellaneous topical agents

What is Capzasin-HP?

Capsaicin is the active ingredient in chili peppers that makes them hot. Capsaicin can be found in medicated lotions and creams that help relieve muscle or joint pain. Capsaicin that is applied to the body triggers a feeling of warmth that stimulates nerve cells. Through the regular use of capsaicin, this heating effect can reduce the quantity of the substance P, which functions as a pain spokesman within the body.

Capzasin-HP is used to provide short-term relief from joint or muscle discomfort caused by strains, injuries, arthritis, bruises, or backaches. It is also employed to manage neural pain (neuralgia) for people who suffer from herpes zoster as well as shingles."

Qutenza is a prescription-strength form of capsaicin topical that is applied by a healthcare professional. Qutenza can be used to treat the pain in the nerves caused by herpes. It can also be used to alleviate foot pain caused by nerves (peripheral neuropathy) for people suffering from diabetes. Capzasin HP can also be utilized to accomplish other functions not mentioned in Capzasin HP's guide.

Side effects Of Capzasin-HP:

Seek medical attention immediately. If you are experiencing warning signs of an allergic reaction, such as symptoms of hives, breathing difficulties, or swelling of your lips, face, or tongue, Cleanse the skin and seek medical attention as soon as you experience extreme pain, burning, or swelling on the area of your skin where you have applied the medicine.

Capzasin-HP may cause serious side effects. Stop using Capzasin-HP immediately and contact your physician immediately in the event that you experience:

  • Extreme pain or redness on the skin in the area where the medication was applied.
  • Loss of sensation;
  • Difficulty breathing or swallowing (after accidental exposure to the capsaicin odor or dried remnants).

Common side effects include a burning or pain sensation that may last for several hours or even days (especially the first time you make use of topical capsaicin).

This is not a comprehensive list of possible side effects, and other effects may also be present. Consult your physician for advice regarding medical adverse effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.


Don't use Capzasin HP if you are allergic to chili peppers or if you've ever experienced any allergic reactions to Capzasin HP.

Capsaicin may create a hot sensation where it is placed. If you experience extreme discomfort or redness on your skin, be sure to wash the surface with soap and cool water.

See a doctor promptly if you notice intense burning, pain, swelling, blisters, or swelling of your skin after you applied the medicine.


Don't take this medication if you are allergic to chili peppers or if you have suffered an allergic reaction to Capzasin-HP.

Inform your doctor if you have ever suffered from:

  • Any sensitivities (especially any allergies) or
  • An illness that is serious medically.

Do not take this medication for anyone under 18 years old without the guidance of a physician.

How to take Capzasin-HP?

Follow the directions on the label or as directed by your physician. The Qutenza brand of capsaicin can only be administered by a healthcare expert and is not available in the form of a prescription. Do not chew it. Topical medicines are meant for use only on the skin.

Capsaicin can be found in a variety of forms, including lotion, cream liquid, or patches for the skin. Be sure to read and follow the instructions for use that come with your prescription. Consult your physician or pharmacist for clarification if you are unsure of these directions. Do not apply Capzasin-HP to open wounds or on sunburned, chapped, dry, or irritated skin. If the medicine is absorbed into your nose, eyes, mouth, rectum, or vagina, wash it off with water.

Make sure that your skin is dry and clean before applying Capzasin HP Cleanse your hands with soap and water right after applying Capzasin HP or handling an application of a patch for the skin. If you've applied the medication to your fingers or hands to ease the pain in those locations, wait a minimum of thirty minutes prior to washing them. To avoid getting this medication on your fingers, use gloves made of rubber, a cotton ball, a finger cot, or a clean towel to apply the medication.

Capsaicin is known to create a burning sensation anywhere it's applied. Even if the medication is applied to a different surface than your skin, you could feel burning when you come into contact with the area. The sensation is typically mild and will gradually diminish over time with regular use of the medication. In the event that burning feels uncomfortable or causes extreme discomfort, clean the affected skin by using soap and cool water. See a doctor immediately if you experience extreme pain, burning, or swelling.

Don't cover the area with a bandage or heating pad, as this could intensify the burning. It is possible to protect the skin by covering it with clothes. Do not bathe or shower for a minimum of 1 hour prior to or following the time you apply capsaicin to your skin. Avoid swimming and hard exercises. Warm water or sweat can intensify the sensation of burning due to capsaicin. Do not get Capzasin HP in your eyes or close to your nose, where you could breathe it in. If it gets into one of these places, wash thoroughly with water.

Be sure to avoid getting this medication on your dentures, contact lenses, or other objects that touch delicate areas of your body.

It can take between two and two weeks of taking the medicine on a regular basis before symptoms begin to improve. To get the best results, continue applying the medicine according to the instructions. The relief from pain should come gradually because the P substance in your body decreases within the nerve cells. Contact your physician if your pain doesn't improve after taking this medication for 7 days or if you notice your symptoms getting worse or improving and return in a couple of days. Store Capzasin HP at room temperature, free of heat and moisture, in a safe place where pets and children can't access it. Capzasin HP liquid is flammable. Don't store or use it close to open flames or near a fire.

What happens If I miss a dose?

Take the missed dose when you remember. Do not take your missed dose if you are nearing the time for the next dose. Don't apply capsaicin more than four times within one day, or apply additional medicine to fill in the missed dose. In case you miss a dose of Capzasin-HP, it does not cause harm; however, it could make the medication less effective in reducing substances P and easing your discomfort.

What happens If I overdose?

For medical emergencies, seek emergency treatment or contact the Poison Help line at 1-800-222-1222, particularly if someone has accidentally swallowed the poison. Capsaicin that is swallowed accidentally can result in severe burning around the mouth and eyes, as well as a runny nose and difficulty breathing or swallowing. Infusing too much Capzasin HP into the skin may cause severe redness or burning.

What should be avoided?

Beware of inhaling the smell or dried residue of the capsaicin topical. When you inhale capsaicin, it can trigger the symptoms of sneezing, coughing, or watery eyes and may cause irritation to your throat and lungs. Avoid touching your mouth, eyes, nose, genitals, or rectum until the medicine is completely removed from your hands. Be sure to avoid touching food when the medication is in your hands. Avoid exposing the treated skin to sunlamps, sunlight tanning beds, sunlamps, or hot water. Capsaicin may create a burning feeling, which can be aggravated by the heat.

Do not apply any other medical products for your skin, such as muscle pain creams or lotions, to the areas where you've applied capsaicin unless your physician has advised you to.

Interaction with other drugs

It's unlikely that other drugs you consume by mouth or inject can affect the capsaicin you apply topically. However, many medications can interact with each other. Be sure to inform your health professionals about any medications you take, including prescription and non-prescription drugs, vitamins, and herbs.