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Banzel

Generic Name: Rufinamide [roo-FIN-a-mide]
Drug Class: Dibenzazepine anticonvulsants

What is Banzel?

Banzel is a seizure drug and is sometimes referred to as an anticonvulsant or antiepileptic. Banzel is used in conjunction with other medications for treating seizures caused by Lennox-Gastaut Syndrome, an extremely severe form of epilepsy that can also cause difficulties with development and behavior. Banzel can be used by adults and children who are 1 year old.

Warnings

It is not recommended to take Banzel when you suffer from severe liver problems or an inherited heart rhythm disorder referred to as the short QT syndrome.

You shouldn't stop using Banzel abruptly unless your doctor advises you to stop the medication due to a serious adverse result. Many people contemplate suicide when taking seizure medications. Be aware of fluctuations in mood or symptoms.

Before you taking this drug

Banzel is not recommended for use. If you have an allergy to rufinamide or you are:

  • A cardiac rhythm disease that is genetically inherited and known as short QT syndrome.
  • A severe liver illness that causes severe liver.

To ensure that Banzel is safe for you, inform your doctor if you have any of the following:

  • Heart disease.
  • Liver disease.
  • Kidney diseases (or if you're taking dialysis).
  • Depression, mental illness, or suicidal ideas or actions.

Certain people contemplate suicide when taking Banzel. Your doctor must examine your progress every few appointments. Your family members and other caregivers should be on the lookout for changes in your symptoms or mood.

Do not begin or stop taking medication for seizures during pregnancy without consulting your doctor's recommendation. Having a seizure while pregnant can be harmful to the mother and the baby. Talk to your doctor when you discover that you are pregnant. If you are expecting, your name might be added to an OB-GYN registry that tracks how rufinamide affects you and the baby.

Banzel can make hormone birth control more ineffective, such as birth pills for control implants, injections, skin patches, and vaginal rings. To ensure that you are not pregnant while taking rufinamide, make use of an alternative to birth control, such as a condom diaphragm, cervical cap, and contraceptive sponge. It might not be safe to breastfeed while taking this medication. Talk to your doctor about any risks. Banzel shouldn't be given to children younger than 1 year old.

How to take a Banzel?

Consume banzel exactly as directed by your physician. Follow all the instructions on the prescription label and go through all the medication guides or instructions. The doctor might alter your dosage. Make sure to take Banzel and eat food. Tablets can be consumed whole, crushed, or cut into two halves.

Make sure to shake your oral suspension (liquid) well just before measuring a dose. Take measurements of the liquid using the dosing syringe as well as the bottle adapter included in the medicine. The adapter should be inserted into the bottle and secured in its place. Inject the syringe into the adapter and then turn the bottle upside down. To determine the amount of dose, you need to pull the plunger until you reach the appropriate milliliters that are printed on the back of the syringe. Wash the syringe with water after use.

Be sure to read and adhere to any instructions that are included with your medicine. Consult your physician or pharmacist for clarification if you are unsure of these directions. Consult your physician. If your seizures become more severe or you experience seizures more frequently when you take Banzel, You shouldn't stop using Banzel abruptly unless your doctor advises you to stop taking the medication due to a serious adverse consequence. The abrupt stop can cause more seizures. Follow the instructions of your physician attentively. Keep the bottle at room temperature. Close the bottle when not being used.

Place the medicine upright. Don't try to remove the adapter from the bottle after it has been put in place. Dispose of Banzel liquid within 90 days of the time when you first opened the bottle, regardless of whether there is medicine still inside. In the event of an emergency Wear or carry medical identification that lets people know that you are using rufinamide.

Details on dosage

Usual Adult Dose for Lennox-Gastaut Syndrome:

The first dose is 400–800 mg daily in two equally divided doses.
Titrate between 400 and 800 mg increments each day until the maximum daily dose in the range of 3200 mg has been achieved.
Dosage for maintenance: 1600 mg taken orally two times every day.
Comments: It is unclear the extent to which doses below 3200 mg/day can be effective.
For patients who are receiving valproate concurrently, the initial doses must be less; refer to the dosage adjustments section.
Uses: As an adjunctive treatment of seizures resulting from Lennox-Gastaut's syndrome.

Usual Pediatric Dose for Lennox-Gastaut Syndrome:

1 year old or more:
Initial dosage: 10 mg/kg/day, orally in two doses equally divided.
In increments of 10 mg/kg every other day until a dosage of 45 mg/kg/day.
Dosage for maintenance: 45 mg/kg taken orally every day, divided into two equally divided doses.
Maximum dose: 3200 mg/day
Comments: It isn't known whether doses that are lower than 45 mg/kg (not over 3200 mg/day) are efficient.
If patients are taking valproate in conjunction with the doses, the first dose should be less; refer to the dosage adjustments section.
Uses: As an adjunctive treatment of seizures that are associated with Lennox-Gastaut Disorder in children one year old or older.

What happens if I miss a dose?

You should take the medicine as fastly as you can. However, avoid your missed dose if it's close to the time of the next dose. Don't take two doses at a time. Make sure you refill your prescription before you run out of medication completely.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line toll-free at 1-800-222-1222.

What should be avoided?

Avoid driving and other hazardous activities until you understand the effects this medicine has on your body. Your reaction could be affected. Drinking alcohol can trigger certain adverse effects of rufinamide.

Side Effects of Banzel

Get immediate medical attention. If you show symptoms that you are experiencing an allergic reaction, Banzel: hives, breathing difficulties, or swelling of your lips, face, and tongue.

Get medical attention in the event of a severe drug reaction that could affect various parts of your body. Symptoms may include a skin rash and fever, swelling of glands, muscle aches, extreme weakness, unusual bruising, or the yellowing of your eyes or skin.

Inform your doctor about any new or worsening symptoms, for example, a change in your mood or behavior, mood swings, anxieties, panic attacks, trouble sleeping, or if you are feeling aggressive, angry, insane, or restless. anxious, hyperactive, and have thoughts of suicide or harming yourself.

See your doctor right away. If you suffer from:

  • Balance loss or coordination.
  • Difficulty walking.
  • Worsening or increased seizures.

Common banzel side effects can include:

  • Headache.
  • Dizziness, drowsiness.
  • Nausea.
  • Feeling exhausted.

This isn't an exhaustive list of possible side effects, and other side effects could be present. Consult your physician for advice regarding medical adverse effects. You can report symptoms to the FDA at 1-800-FDA-1088.

Interaction with other drugs?

Utilizing Banzel together with other medications that cause you to become drowsy could increase the severity of this effect. Talk to your doctor prior to using opioids, sleeping pills, muscle relaxers, or medication for seizures or anxiety.

Inform your doctor about all other medicines you take, including:

This list is not comprehensive. Other medications may be a cause of interaction with rufinamide, such as prescription and over-the-counter medicines, vitamins, and herbal products. Some interactions with drugs are not listed here. are listed here.

DRUG STATUS

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Prescription only

Pregnancy & Lactation

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