The Web Health



Name of the Generic: Azelastine Hydrochloride

Name of Brands: Astepro and Astelin

Dosage Format: Nasal Spray, Metered

Classification of Drugs: Nasal Antihistamines and Decongestants

What is Azelastine?

Azelastine hydrochloride nasal spray is an antagonist of the H1 receptor that is indicated to treat symptoms associated with the seasonal allergic rhinitis of adult and pediatric patients aged five and above as well as for treating symptoms associated with vasomotor rhinitis in adolescents and adults who are 12 or older.


The risk of developing a sense of numbness is to avoid dangerous jobs requiring complete alertness, such as driving, operating machinery, or even using the nasal spray azelastine.

Alcohol and other Central nervous system (CNS) depressants should be avoided using Azelastine in combination with nasal spray, as further reduction in awareness and impaired CNS functioning could result.

Before You Take this Medication

The most frequent adverse reactions (>=2 percent of frequency) are bitterness, acrid taste, and headaches, as well as somnolence and rhinitis and dysesthesia burning, epistaxis, pharyngitis nasal sneezing, sinusitis and dry mouth, nausea, and fatigue. They also experience dizziness, dizziness, and weight gain.

Azelastine Hydrochloride nasal spray is recommended for the treatment of the signs and symptoms of seasonal allergic rhinitis in adult patients and children five years old and over and also for the treatment of the signs and symptoms of vasomotor rhinitis in adolescents and adults who are 12 or older.

  • Clinical trials have revealed that somnolence-related symptoms have been documented in nasal spray patients.
  • Patients should be warned to avoid engaging in dangerous occupations requiring complete alertness to the mind and motor coordination, like operating machines or a motor vehicle, following treatment with azelastine hydrochloride nasal spray.
  • Azelastine hydrochloride nasal spray and alcohol, or any other central nervous system stimulants, is not recommended due to the possibility of a further decrease in alertness, as well as further impairment of the central nervous system could occur.

How to Take Azathioprine?

There have been no reports of adverse reactions to azelastine hydrochloride's nasal spray. An acute dose of the drug by adult users using this dosage is likely to produce adverse severe reactions clinically, aside from somnolence escalating, because one bottle of the azelastine Hydrochloride spray for nasal use contains thirty mg of Azelastine chloride.

Studies conducted on adults using only a single dose of the oral formulation of azelastine chloride (up to 16 mg) did not show more serious adverse reactions. A general approach to support must be taken if there is an overdose. There is currently no antidote to the nasal spray azelastine hydrochloride. Ingestion of antihistamines through the mouth can cause severe adverse reactions in children. Therefore, nasal azelastine spray must be kept out of the reach of young children.

What Happens If I Miss a Dose?

It would help if you took your dose as soon as you remember. Take just one dose if you only remember it two hours before the next dose is scheduled. Don't think of having two doses in one go. It could lead to dangerous negative side adverse effects.

What Happens If I Overdose?

If you are overdosing, You could be a danger to the drug within the body. Signs of an excessive dose of this substance can include drowsiness. See a doctor in emergencies or contact for help at the Poison Help line toll-free at 1-800-222-1222.

What Should be Avoided?

Beware of sun exposure as well as a tanning bed. Azathioprine can increase the risk of getting skin cancer. Wear protective clothing and apply sunscreen (SPF 30 or more) when outside in the sun.

Take note of anyone who is infected or sick. Tell your doctor right away if you exhibit signs of illness.

Do not receive or receive any "live" vaccine while using Azelastine. It may not perform similarly or entirely safeguard you against ailments. Live vaccines protect against measles, rubella, and Mumps (MMR) along with Typhoid virus, polio, yellow fever, rotavirus varicella (chickenpox), and Zoster (shingles).

Side Effects of Azelastine

The most frequent adverse side effects associated with Azelastine nasal spray could be:

  • Febrile
  • The bitter taste on your tongue
  • Nosebleeds
  • Headache
  • Drool
  • Upper respiratory tract infections
  • Vomiting
  • Otitis externa
  • Skin rash

They may disappear within a couple of days or weeks. Discuss the issue with your physician or pharmacist if the symptoms are more intense or do not go away.

Mild Effects

  • Cough
  • Sneezing
  • Sore throat
  • Nasal sensation or discomfort

The following briefly lists potential side consequences; additional effects could occur. Talk to your doctor about medical adverse reactions.

Adverse Effects

Take a break from Azelastine and consult your physician promptly if you experience one of the symptoms of lymphoma.

  • Mucusy nosebleeds or a mystery cause.
  • Dizziness
  • Dryness in the mouth
  • Muscle aches, pains, or numbness
  • Nausea
  • Rapid outbursts, screaming
  • Weight gain

Interaction with Other Drugs

  • 1,2-Benzodiazepine 1,2-Benzodiazepine can increase the central nervous system's depression (CNS depressant) functions of Azelastine.
  • Abametapir, The concentration in the serum of Azelastine may increase when combined with Abametapir.
  • Abatacept Azelastine metabolizes it and may be enhanced when it is it is combined with Abatacept.
  • Abiraterone, The blood concentration of Azelastine is increased by combining it with Abiraterone.
  • Abrocitinib Its metabolism Abrocitinib is reduced when it is combined with Azelastine.
  • Acalabrutinib is a drug that slows the metabolism. Azelastine may be reduced when it is combined withvb
  • Acebutolol Its metabolism Acebutolol may be reduced in combination with Azelastine.
  • Acenocoumarol metabolizes Acenocoumarol and may be reduced in combination with Azelastine.


Prescription only

Pregnancy & Lactation

CSA Schedule*
Related Drugs
Related Stories