The Web Health


Aspirin (rectal)

Generic name: aspirin (rectal) [AS-pi-rin]
Dosage format: rectal suppository (300 mg)
Drug classes: platelet aggregation inhibitors, salicylates

What is Aspirin (rectal)

Aspirin can be described as an alicylate.Aspirin for the rectal (for use in the rectal area) serves to manage high fever or to ease minor aches, pains, and headaches.Rectal aspirin can also be used to treat conditions that are not mentioned in this guide.

Side effects of Aspirin (rectal)

Contact a medical professional immediately. Get medical attention immediately if you notice symptoms that indicate an allergic reaction, such as difficulty breathing, hives, and swelling of your lips, face, tongue, throat, or face.

Rectal aspirin may cause serious side effects. Stop taking rectal aspirin and consult your physician immediately if you experience:

  • Bleeding or bruising;
  • Wheezing, chest tightness, coughing, running, or stuffy nose;
  • Ears ringing, hearing loss;
  • Dizziness, confusion,
  • Stomach bleeding, bloody or tarry stools bleeding from the stomach, coughing blood or vomit that resembles coffee grounds

The most common serious side effects include irritation to the rectal.This list does not encompass every potential side effect. Others could happen. Consult your physician for advice regarding medical adverse effects. Your adverse reactions should be reported directly to the FDA at 1-800-FDA-1088.

Similar or related drugs

Cosentyx, Simponi, Saphnelo, amlodipine, lisinopril, metoprolol, and aspirin


Follow all instructions on the label as well as on the packaging. Make sure you use the product exactly as it is indicated.

Before you take this drug

It is not recommended to make use of Aspirin if you have an allergy to Aspirin or any NSAID (nonsteroidal anti-inflammatory medication) like ibuprofen (Advil, Motrin), naproxen (Aleve), or celecoxib, diclofenac (indomethacin), diclofenac (d), and many more.Do not give aspirin to children under 12 years of age without medical guidance. If you use this medication on a teenager or child suffering from symptoms of flu manifestations as well as chickenpox, it could result in an extremely fatal disease known as Reye's syndrome.

Consult a pharmacist or doctor for a recommendation on whether this medication is suitable for you if you previously had:

  • Bleeding issues;
  • Asthma or a severe allergic reaction (sneezing, running, or stuffy nose wheezing) following the use of aspirin or any other nsaid;
  • A stomach ulcer or bleeding
  • Kidney disease.

Talk to your doctor prior to taking this medication if you are breastfeeding or pregnant.Aspirin use during the last stages of pregnancy can cause bleeding, either in the mother or the baby during the birth.

How to take Aspirin (rectal)?

Follow the directions provided on your label or as instructed by your doctor.Do not consume by mouth. Rectal medicine can be used only within the rectum.Take note of all the instructions for use. Talk to your pharmacist or doctor for assistance.Take off the wrapper prior to inserting the suppository.Lay on your back with your legs bent. Place the suppository gently on your back as deep as you can, pointing at the tip first.Lay down for a couple of minutes. There should be no discomfort when the liquid suppository is melting. Do not use your bathroom for more than an hour.Don't use this medicine for more than 10 days. Contact your physician if you persist with a fever even within 3 days or if you are still experiencing pain over the course of 10 days or are experiencing any swelling, redness, or other new signs.This medication can alter the outcomes of certain medical tests. Be sure to inform any doctor treating patients that you're using rectal aspirin.Inform your doctor if you are planning a procedure.Suppositories should be stored at a cool ambient temperature or in the refrigerator.

What happens if I miss the dose?

Rectal aspirin is usually used when it is needed. If you're on a schedule for dosing, you should skip missed doses. Do not take two doses at the same time.

What happens if I overdose?

For medical emergencies, seek emergency treatment or contact for help at the Poison Help Line at 1-800-222-1222, in particular if you suspect that someone has taken the medication.Overdose symptoms can consist of headaches or severe tiredness, drinking, vomiting, hallucinations, breathing issues, muscle twitching, or seizures.

What should be avoided?

Talk to your doctor prior to using rectal aspirin when you take an antidepressant. When you take some antidepressants along with an NSAID, it can cause bleeding or bruises easily.Drinking alcohol can increase your risk of bleeding in your stomach.Consult a doctor before taking over-the-counter medications that could contain aspirin-like ingredients (such as ibuprofen, ketoprofen, naproxen, or ketoprofen).

Interaction with other drug

Consult a physician or pharmacist before utilizing rectal aspirin along with any other medications, particularly:

  • Medicines to treat the conditions of gout and joint pain;
  • Diabetes medicine;
  • A blood thinner (warfarin, coumadin, jantoven)

This list is not comprehensive. Other drugs can interact with rectal aspirin. This includes medications that are prescribed and available over the counter, vitamins, and herbal products. There are many possible interactions between drugs that are included here.




Prescription only

Pregnancy & Lactation

CSA Schedule*
Related Drugs
Related Stories