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Aspirin and Omprazole

Generic name: aspirin and omeprazole [AS-pir-in-and-oh-MEP-ra-zole]
Brand name: Yosprala
Dosage format: oral delayed release tablet (325 mg–40 mg) (81 mg–40 mg)
Drug class: platelet aggregation inhibitors

What are Aspirin and omeprazole?

Aspirin and Omeprazole can be described as a mix of medications that helps lower your risk for heart issues, strokes, death, or even death for those who have suffered heart problems due to blood clots.Aspirin and omeprazole are also employed in those who have undergone operations to increase the flow of blood to the heart and who also have another issue that is currently being treated with aspirin.Omeprazole reduces your risk for stomach ulcers that could result from aspirin, particularly for those over 55 or who have had stomach ulcers previously.Omeprazole and aspirin can be used to treat conditions that are not covered in this guide.

Side effects of Aspirin and Omeprazole

Seek medical attention immediately. If you are experiencing symptoms that indicate an allergic reaction, such as running, sneezing, or nasal congestion; wheezing or difficulties breathing or hives; or swelling of your lips, face, or tongue,

Omeprazole and aspirin can cause severe adverse effects. Consult your physician immediately if you suffer from:

  • Extremely severe nausea, vomiting, stomach pain, and diarrhea that is swollen or bloody.
  • The stool is bloody or tarry and coughs up blood, or it looks similar to coffee grounds.
  • Bleeding that is not normal, easy to bruise (such as a nosebleed), or bleeding that will not stop;
  • Suddenly experiencing pain or difficulty moving your wrist, hip, or back
  • Kidney problems: symptoms of kidney problems include fever, rash, nausea, lack of appetite, joint pain, a lower frequency of urination, increased weight, and bloody urine.
  • Problems with the liver: stomach symptoms, itching, dark urine, jaundice (yellowing of the eyes or skin);
  • Low magnesium intake may result in dizziness, fast or irregular heartbeat rate, muscle tremors (shaking/jerking movements), feeling of being "jittery", muscle cramps/ spasms in your hands/feet/cowering sensation and cough or choking;
  • The symptoms are either getting worse or new for the lupus—joint pain, as well as an itch on your arms or cheeks that gets worse in the sun.

Long-term use of aspirin or omeprazole can cause stomach-related growths, also known as fundic polyps. Discuss this possibility with your physician.If you take this medication for longer than three years, you could be developing a vitamin B-12 deficiency. Consult your physician about how to deal with this issue in the event that you are diagnosed with it.

Common adverse effects of aspirin and Omprazole can include:

  • Heartburn, stomach pain stomach pain, indigestion
  • Nausea, diarrhea,
  • Chest pain in the chest (may occur after eating).

This list does not constitute an exhaustive compilation of side effects. Others could happen. Consult your physician to seek medical advice on the effects. Report any symptoms to the Food and Drug Administration by calling their hotline, 1-800-FDA-1088.


Aspirin can cause you to suffer from bleeding more frequently. Call your doctor in the event of unusual bleeding or bruising, in the event that you are coughing up blood, or in the event that you have bloody or tarry stool.Omeprazole can cause kidney damage. Inform your doctor that you're not urinating as much as normal or if you notice the presence of blood in your urine.Diarrhea could be a sign of a newly developed illness. Consult your doctor for a visit if you are suffering from diarrhea that is swollen or has the presence of blood.Omeprazole can result in the onset or worsening of lupus symptoms. Inform your doctor if you suffer from joint pain or a red rash on your arms or cheeks that worsens when exposed to sunlight.You could be more likely to suffer fractured bones when you take this medication for a long time or more than one time every day.

Before you take this drug

It is not recommended to make use of aspirin or omeprazole when you have an allergy to either omeprazole or aspirin or if you suffer from:

  • You may also be allergic to medications such as esomeprazole, pantoprazole, lansoprazole, Nexium, Prevacid, Protonix, and others.
  • You take a medicine that contains the ingredient rilpivirine (Edurant, Complera Juluca, Odefsey);
  • You've experienced you've had an asthma attack or a severe allergic reaction (sneezing or runny nose wheezing, discomfort in the chest, shortness of breath) after taking aspirin or a different NSAID
  • If you've had breathing problems, kidney issues, or an extreme allergic reaction following taking this medicine previously,

Omeprazole or aspirin shouldn't be used to treat sudden stroke or heart attack manifestations (chest pain, sudden numbness, or weakness of speech).This medication is not recommended for use by anyone younger than 18 years of age. Aspirin may cause Reye's syndrome, which is a grave and often fatal condition for children.

Speak to your doctor if you were ever diagnosed with:

  • A blood disorder such as vitamin K deficiencies;
  • Low levels of magnesium in your blood.
  • An habit of taking more than three daily alcoholic drinks;
  • Kidney or liver disease;
  • Lupus;
  • If you're of Asian descent,

It is possible that you are more likely to suffer fractured bones in your wrist, hip, or spine if you are taking this medication for a long time or more than once daily. Talk with your doctor about ways to ensure your bones are healthy.In the last stages of pregnancy, it could cause bleeding in the baby or mother during the birth. Tell your doctor if you're pregnant or planning to be pregnant.The medicine could temporarily alter the chances of becoming pregnant. Consult a physician if this is of concern to you.It is not recommended to breastfeed when taking aspirin or omeprazole.

How to take Aspirin and Omprazole?

Follow the instructions on the prescription label and study all medication guides and instructions sheets. Make sure you are using the dose that will treat your condition.Consume this medicine along with the full cup of liquid. The recommended dosage is every day, one hour prior to a meal.Take the tablet in one swallow and make sure you don't crush, chew, or break it.This medication can alter the outcomes of certain tests. Be sure to inform any doctor who treats you about taking aspirin or omeprazole.Omeprazole could affect a drug-screening urine test and cause you to get inaccurate results. Inform the lab personnel that you are taking aspirin and omeprazole.Be careful not to stop taking the medicine abruptly, even if you are feeling well. The abrupt stoppage could increase the chance of having a coronary heart attack as well as a stroke. Follow the instructions of your physician about the process of tapering your dose.Keep the tablets at room temperature, far from heat and moisture. Place the tablets in the original container together with the package or canister of preservative that absorbs moisture.

What happens if I miss the dose?

Do not take the medicine for as long as you can; however, take a break from your missed dosage if you are nearing the time to take the next dose. Don't take two doses at a time unless your doctor advises you to.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help Line toll-free at 1-800-222-1222.The symptoms of an overdose could include ear ringing, an increase in drink, muscle pain or weakness, difficulty breathing, as well as being cool.

What should be avoided?

Consult a physician or pharmacist prior to using any over-the-counter medications. They could contain ingredients that are similar to omeprazole or aspirin.Aspirin that is taken regularly with omeprazole (Prilosec) is not similar to taking the combination of omeprazole and aspirin (Yosprala). Do not substitute aspirin or omeprazole for over-the-counter products.Alcohol consumption can increase the chance of bleeding from your stomach.

Interaction with other drug

There are times when it's not recommended to take certain medicines simultaneously. Certain drugs may affect the blood levels of the other drugs that you take, which can create side effects or render the medication less effective.

Inform your doctor about the medicines you are taking currently. A variety of drugs can impact aspirin and omeprazole. Especially:

  • Clopidogrel;
  • Digoxin;
  • Methotrexate;
  • Rifampin;
  • John's wort;
  • Ticagrelor;
  • Diuretic, also known as a "water pill."
  • These are nsaids (nonsteroidal anti-inflammatory drugs): aspirin, ibuprofen (advil, motrin), naproxen (aleve), celecoxib, diclofenac, indomethacin, meloxicam, and many others.

This list isn't complete, and other drugs could impact aspirin and omeprazole. This includes over-the-counter and prescription drugs, vitamins, and herbal supplements. There are many possible interactions between drugs that are included here.




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