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Amphotericin B lipid complex

Generic name: amphotericin B lipid complex [AM-foe-TER-i-sin-B-LIP-id-KOM-plex]
Brand name: Abelcet
Dosage format: intravenous suspension (5 mg/mL)
Drug class: polyenes

What is Amphotericin-B Complex?

Amphotericin-B Lipid Complex can be described as an antifungal drug that is prescribed to cure severe, potentially life-threatening fungal diseases that aren't treatable with other antifungal drugs.

Amphotericin B's lipid complex could be utilised for other purposes that are not mentioned in this guideline.

Side effects of Amphotericin-B Complex

Contact a medical professional immediately. Get medical attention immediately if you notice symptoms that indicate an allergic reaction, such as hives, difficulty breathing, and swelling of your lips, face, and tongue.

Certain side effects can occur after the injection. Inform your doctor immediately when you experience a fever or are lightheaded. Also, you may feel shaky.

Amphotericin B's lipid complex could result in serious side effects. Contact your physician immediately. If you suffer from:

  • New or worsening new or worsening cough, wheezing, difficulty breathing;
  • Blue lips blue lips, blue-coloured fingers and toes;
  • Easily bleeding, unusual appearance of red or purple spots beneath the skin
  • Slow heart rate low pulse, fainting, and slow breathing (breathing could be stopped);
  • Kidney issues: little or no urinary frequency; swelling of your ankles or feet; feeling tired or weak;
  • Low calcium levels—muscle spasms or tension, numbness, or sensation of tingling;
  • Low magnesium—dizziness, irregular heartbeats, feeling jittery, muscle cramps, muscle spasms, coughing or choking feeling;
  • Lower potassium level: leg cramps, constipation fluttering around your chest, an increase in thirst or urination also, muscles are weakening or there is a limp sensation.

Common side effects of the amphotericin-b complex of lipids could be:

  • Fever, chills;
  • Nausea, vomiting,
  • Abnormal kidney function tests for abnormal kidney function

This list doesn't encompass every potential side effect. Other side effects could occur. Contact your physician to seek medical advice on adverse effects. Report any adverse reactions directly to the FDA by calling them at 1-800-FDA-1088.


Inform your healthcare providers that you are feeling ill, lightheaded, shaky, or breathless when you're receiving the amphotericin-B lipid compound.

Before you take this drug

It is not recommended to be treated with amphotericin A if you are allergic to it.

Speak to your doctor if you ever have:

  • Kidney disease;
  • The transfusion of blood cells;
  • The imbalance of electrolytes (such as low or high levels of magnesium, potassium, or magnesium in the blood).

It isn't known if this medication could cause harm to a baby who is not yet born. Inform your doctor if you are expecting or planning to be pregnant.

It is not recommended to breastfeed during the use of the amphotericin-B lipid complex.

How to take Amphotericin-B Complex?

The amphotericin B complex of lipids can be given by infusion into the vein. Your healthcare provider will offer the injection.

Amphotericin B lipid complex has to be administered slowly, and infusions can be up to two hours long before they are completed.Your liver and kidney function and electrolytes are checked regularly.

What happens if I miss the dose?

If amphotericin-B lipid complex is administered while you are in the hospital, there is no reason for you to miss a dose.If you're receiving this medication at an outpatient facility, please call your doctor to inquire about the procedure when you don't make an appointment for the amphotericin B injection of the lipid complex.

What happens if I overdose?

Because amphotericin B lipid complex is prescribed by a health expert in a medical environment, the risk of overdose is low.

What should be avoided?

Follow your doctor's advice regarding any limitations on foods, drinks, or activities.

Interaction with other drugs

Amphotericin B may affect your kidneys, specifically in conjunction with certain medications to treat osteoporosis, cancer, infections, rejection of organ transplants, intestinal problems, and high blood pressure or arthritis pain (including Advil, Motrin, and Aleve).

Inform your doctor of all medications you are currently taking, particularly:

  • Corticotropin (ACTH);
  • Digoxin, digitalis;
  • Zidovudine;
  • Other antifungal medicine—clotrimazole, fluconazole, ketoconazole, miconazole,
  • Steroid medicine—dexamethasone, prednisone, methylprednisolone, and others.

This list isn't exhaustive. Other medications may interact with amphotericin B's lipid complex, which includes prescription and over-the-counter medications, vitamins, and herbal products. The interactions of all drugs are included here.