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Amlodipine, hydrochlorothiazide, and valsartan

Generic names: amlodipine, hydrochlorothiazide, and valsartan [am-LOE-di-peen, HYE-droe-klor-oh-THYE-a-zide, val-SAR-tan].
Brand name: Exforge HCT
Dosage format: oral tablet (10 mg, 12.5 mg to 160 mg) 10 mg-25 mg-160 mg 10 mg-25 mg-320 mg 5 mg-12.5 mg-160 mg (5 mg-25 mg-160 mg)
Classification of drugs: miscellaneous antihypertensive combination

What is Amlodipine, hydrochlorothiazide, and Valsartan?

Amlodipine blocks calcium channels. Hydrochlorothiazide is a diuretic thiazide (water pill). Valsartan can be described as an angiotensin II receptor blocker (sometimes referred to as the ARB).Amlodipine hydrochlorothiazide, amlodipine, and valsartan are three types of medication used for treating hypertension.Amlodipine, hydrochlorothiazide, and Valsartan are usually prescribed following the administration of other blood pressure medications that failed to work. not perform as expected.Amlodipine hydrochlorothiazide, amlodipine, and valsartan can be used for other purposes that are not mentioned in this guide.

Side effects of Amlodipine, hydrochlorothiazide, and Valsartan

Seek medical attention immediately. If you are experiencing symptoms or warning signs of an allergic reaction, such as asthma, hives, or swelling of your lips, face, and tongue,

Amlodipine hydrochlorothiazide, amlodipine, and valsartan can result in serious adverse effects. Consult your physician right away if you experience:

  • A feeling of lightheadedness, as if you're about to pass out.
  • An unusual skin rash;
  • Blurred vision eyes pain, tunnel vision, or seeing halos of light sources;
  • Excessive levels or high levels: leg cramps, sickness, constipation, irregular heartbeats, the chest fluttering, more frequent urination, or thirst tingling or numbness, muscular weakness, or a limp sensation
  • Kidney issues: little or no urine output; swelling of your ankles or feet; being fatigued or tired;
  • Low magnesium level: dizziness or feeling anxious, muscle cramps or muscular spasms, coughing or choking feeling;
  • Low sodium levels low sodium levels, headaches, and confusion. It can also cause rapid speech, severe fatigue, vomiting, an inability to move, and feeling unstable.

Common adverse effects of amlodipine hydrochlorothiazide, as well as valsartan, can be:

  • Dizziness;
  • Headache, tiredness;
  • Nausea, upset stomach;
  • Sinus pain, stuffy nose, sore throat
  • Back pain, muscle spasms, back pain,
  • Swelling in your ankles, hands, or feet.

This is not a comprehensive list of possible side effects, and other side effects could occur. Consult your physician for advice regarding medical adverse effects. It is possible to report any adverse negative effects to the FDA by calling 1-800-FDA-1088.

Similar or related drugs

amlodipine, lisinopril, metoprolol, losartan, furosemide, and hydrochlorothiazide

Warnings

It is not recommended to use this medication if you are sensitive to Sulfa medications or cannot urinate.Avoid using it if you are expecting. Stop taking the medication and inform your doctor right away in the event that you become pregnant.If you suffer from diabetes, avoid taking amlodipine or hydrochlorothiazide. the drug valsartan with any other medicine that includes an ingredient called aliskiren (a blood pressure medication).

Prior to use this drug

This medicine is for you if you're allergic to hydrochlorothiazide, amlodipine, or valsartan.

  • If you're allergic to any sulfa medication,
  • If you're unable to eliminate

If you are diabetic, don't take amlodipine or hydrochlorothiazide. Valsartan in conjunction with any other medication that includes an ingredient called aliskiren (a blood pressure medication)It is also possible to stay clear of taking this medication along with the drug aliskiren in the event of kidney problems.

Speak to your doctor if you were ever diagnosed with:

  • Heart-related problems;
  • The imbalance of electrolytes (such as low concentrations of magnesium or potassium within your blood);
  • Blood calcium levels are excessively high.
  • Kidney disease (or if you're taking dialysis)
  • Liver disease;
  • Glaucoma;
  • Gout or an increase in levels of uric acids in your blood
  • Lupus;
  • Gallstones;
  • Penicillin is a penicillin allergy.

Don't use it if you are expecting. Stop taking the medication and notify your doctor immediately if you find yourself pregnant. Valsartan could cause death or injury to the baby's unborn when taken during the third or second trimester.It is recommended not to breastfeed when using this medicine.

How to take Amlodipine, hydrochlorothiazide, and Valsartan?

Follow the directions on the prescription label and go through all medication guides or instructions. Your doctor might alter your dosage. Take the medicine exactly according to the instructions.You can take this medicine either with or without food.The pain in your chest may get more intense when you first begin using this medication or when the dose is increased. Consult your physician if you feel your chest pain has become severe or continues to persist.It is possible to become dehydrated after taking this medicine. Drink plenty of fluids throughout the day.Your blood pressure should be regularly checked.Some factors could cause blood pressure levels to go too low. This could include nausea, diarrhoea, or excessive sweating. Consult your physician if you are suffering from vomiting or diarrhoea.If you are in need of an operation or dental surgery, inform the dentist or surgeon beforehand that you're taking this medicine.It can take as long as two weeks before your blood pressure increases. Continue to take this medication according to the directions, even if you do not feel healthy. The high blood pressure is often accompanied by no signs. It is possible that you will need blood pressure medications throughout your life.Place it in a cool, dry place far from heat and moisture.

Details on dosage

Usual Adult Dose for Hypertension:

Initial dosage: 1 tablet taken daily, orally. The dose can be increased after two weeks of treatment. The full blood pressure reduction effect was seen two weeks after having been on the highest dosage.
Maximum dose: amlodipine/hydrochlorothiazide/valsartan 10 mg/25 mg/320 mg orally once a day.Comment:
Patients with blood pressure that is well managed by valsartan, amlodipine, and hydrochlorothiazide (as single component formulations or as a dual component formulation that has one component formulation) Dose titration for every component of the formula is advised prior to giving this fixed dosage combination.

What happens if I miss the dose?

Do not take the medicine for as long as you are able, but avoid your missed dosage if you are close to the time of the next dose. Don't take two doses at a time.

What happens if I overdose?

In case of medical emergencies, get urgent medical attention. You can also call for assistance at the Poison Help Line at 1-800-222-1222.

What should be avoided?

Avoid using the potassium supplement or salt replacement only if your physician has instructed you to.Alcohol consumption with this medicine could cause adverse consequences.Hydrochlorothiazide could increase the chance of developing skin cancer. Avoid sun exposure or tanning beds. Protect yourself with clothing that is breathable and sunblock (SPF 30 or greater) whenever you're outside. Your physician may ask you to take skin tests every few months.Do not get up too quickly from a lying or sitting position, as you could be dizzy. Avoid driving or doing any hazardous activity until you are aware of what the effect of this medicine is on you. Your reaction could be affected.

Interaction with other drugs

There are times when it's not recommended to take certain medicines in combination. Certain drugs may affect the blood levels of the other drugs you are taking, which could create side effects or render the drugs less effective.

Discuss with your doctor your current medications. Numerous medications can interact with amlodipine, hydrochlorothiazide, and valsartan, specifically:

  • Another diuretic, also known as a "water pill";
  • Other blood pressure medications;
  • Insulin, or oral diabetes medicine;
  • Steroid medicine;
  • Vitamin or mineral supplements that contain potassium
  • A sedative or opioid medication;
  • Cholesterol-lowering medicine;
  • An antibiotic or antifungal medication; an antiviral medication;
  • The nsaids (nonsteroidal anti-inflammatory drugs) are aspirin, ibuprofen (advil, motrin), naproxen (aleve), and many more.

This list isn't complete, and other drugs could be affecting amlodipine, hydrochlorothiazide, and valsartan. This includes both over-the-counter and prescription drugs, vitamins, and herbal products. The list of possible interactions with drugs is not exhaustive. are listed here.

 

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