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Name of the generic: amiloride [ A-MIL-o-ride [ a-MIL-o-ride
The brand name: is Midamor.
Dosage format: oral tablet (5 mg)
Drug class: potassium-sparing diuretics

What is Amiloride?

Amiloride is a diuretic that has potassium as a component (a water pill), which prevents your body from taking in too much salt. It also keeps the levels of potassium from getting low.Amiloride is a medication used for treating or preventing hyperkalemia (low potassium levels in the blood) in those suffering from excessive blood pressure and congestive heart failure.Amiloride is typically given along with other medications.Amiloride can also be employed for other purposes that are not covered in this guideline.

Side effects of Amiloride

Contact a medical professional immediately. Get medical attention immediately if you notice symptoms or warning signs of an allergic response, like hives, trouble breathing, and swelling of your lips, face, and tongue.

Stop taking amiloride immediately and contact your doctor immediately. If you suffer from:

  • Increased thirst, less urine production;
  • Sweating, heavy sweating, or dry and hot skin;
  • Tsunamis, confusion, and loss of consciousness
  • Jaundice (yellowing of the eyes or skin);
  • High potassium--tiredness, numbness or tingling, slow or unusual heart rate, muscle weakness or limp feeling;
  • Low levels of sodium in the body. Headache, headache, confusion, speech slurred, extreme fatigue, vomiting, lack of coordination, feeling unstable

Common side effects of amiloride include:

  • Nausea, stomachache gas, nausea as well as a loss of appetite.
  • Headaches,

It's not a comprehensive listing of all possible adverse consequences, but other effects might occur. Consult your physician for medical advice about the consequences. It is possible to report any symptoms to the FDA by calling 1-800-FDA-1088.


Amiloride should not be used when you suffer from kidney problems, are unable to urinate, or have excessive levels of potassium in your blood. Avoid taking potassium-based supplements or diuretics when you take amiloride.Amiloride can increase the amount of potassium present in the blood. It is recommended to have frequent blood tests while taking amiloride.Contact your doctor immediately. If you experience unusual tiredness, tingling of weak muscles, slow heartbeats, or a limp sensation,

Prior to use this drug

It is not recommended to use amiloride when you are allergic to it or:

  • You suffer from kidney disease or you are in a position to not purify;
  • You have issues with your kidneys due to your diabetes.
  • If you're suffering from an excessive amount of potassium (hyperkalemia),
  • If you are taking a potassium supplement,
  • You can also take potassium-sparing diuretics such as moduretic, spironolactone, and triamterene.

To ensure that amiloride is safe for you, consult your physician if you suffer from:

  • Diabetes;
  • Heart disease;
  • Breathing issues;
  • The cirrhosis or any other liver diseases;
  • If you're on an e-diet that is low in salt,
  • If you're seriously ill or have a debilitating condition,

Amiloride isn't expected to harm an unborn child. Inform your doctor if you are pregnant or planning to be pregnant while taking this medication.It is unclear if amiloride is absorbed into breast milk or whether it can harm a nursing infant. Do not breastfeed when taking this medication.

How to take Amiloride?

Follow the instructions on the label of your prescription. Your doctor might alter the dosage to ensure that you receive the most effective outcomes. Avoid using amiloride in smaller or larger quantities or for longer periods than suggested. Eat amiloride in conjunction with food.Your doctor might suggest eating certain food items or taking supplements to stop your potassium from becoming too low. Be sure to follow the diet and medication programme recommended by your physician or nutritionist.When you are taking amiloride, you'll require regular blood tests. The function of your heart may have to be assessed by using an electrocardiograph, or ECG (sometimes known as the EKG).This medication can alter the outcomes of certain medical tests. Be sure to inform any doctor who treats you about your use of amiloride. It is possible that you will need to cut off amiloride for at least three days prior to having a glucose tolerance test.Maintain at room temperature and free of heat, moisture, or freezing temperatures.

Details on dosage

Usual Adult Dose for Ascites:

Initial dosage: 5 mg orally every day, once.
Maintenance dose: 5–10 mg once a day.

Usual Adult Dose for Congestive Heart Failure:

Initial dosage: 5 mg daily, orally.
Maintenance dose: 5–10 mg once a day.

Usual Adult Dose for Oedema:

Initial dosage: 5 mg taken daily, orally.
Maintenance dose: 5–10 mg once a day.

Usual Adult Dose for Hypertension:

Initial dose: 5 mg taken orally every day, once.
Maintenance dose: 5–10 mg once a day.

What happens if I miss the dose?

You should take the missed dose as soon as you can remember. Avoid your missed dosage if it's nearing the time for the next dose. Do not take additional medication to compensate for the dose you missed.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help Line toll-free at 1-800-222-1222.

What should be avoided?

Avoid using salt substitutes or milk products with a low sodium content, which contain potassium. These foods could make your potassium levels increase too much while you take amiloride.Beware of a diet that is high in salt. Salt intake too high can result in your body's ability to hold water, which can make the medication less efficient.Amiloride in alcohol can result in adverse effects.Avoid becoming too hot or dehydrated when exercising, in the heat, or by having a deficiency in fluids. Follow the advice of your physician about the types and amounts of fluids you need to consume. In certain situations, drinking too much liquid can be just as harmful as drinking too little.

Interaction with other drugs

Inform your doctor about all the medications you currently take and all you are about to start or stop taking, particularly:

  • Lithium;
  • Medicine to prevent organ transplant rejection—cyclosporine, tacrolimus;
  • An ace inhibitor (angiotensin conversion enzyme)—benazepril captopril, fosinipril, lisinopril, moexipril, and perindopril; quinapril, ramipril, or trandolapril
  • Heart or blood pressure medication--azilsartan, candesartan, eprosartan, irbesartan, losartan, olmesartan, telmisartan, valsartan; or
  • These are nsaids (nonsteroidal anti-inflammatory drugs): aspirin, ibuprofen, aspirin (advil, motrin), naproxen (aleve), celecoxib, diclofenac (also known as indomethacin), diclofe, and others.

This list isn't complete. Other medications can interact with amiloride. These include prescription as well as over-the counter supplements, vitamins, as well as herbs.The interactions of amiloride aren't all included in this guideline for medication.




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