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Generic name: bevacizumab [bev-a-CIZ-oo-mab]
The brand names are: Alymsys, Avastin, Mvasi, Vegzelma, and Zirabev.
Drug class: VEGF/VEGFR inhibitors

What is Alymsys?

Alymsys is a treatment for adults, either on its own or in combination with treatments for cancer. treatment options to combat specific kinds of brain tumours and certain kinds of kidney cancer, such as lung, liver, colon, rectum, ovary, cervix, or fallopian tube.Alymsys can also be used to treat cancers of the membrane that lines the internal organs of the abdomen. It is usually prescribed as a component of a mix of chemotherapy drugs.Alymsys can also be used for reasons not mentioned in this guideline for medication.

Side effects of Alymsys

Contact a medical professional immediately. Get medical attention immediately if you show symptoms or warning signs of an allergic reaction that include hives, trouble breathing, or swelling of your lips, face, and tongue.Certain side effects can occur when you inject. Contact your doctor immediately if you feel faint, nauseated, dizzy, or sweaty. or experience headaches, chest tightness, back discomfort, breathing difficulties, or swelling on your face.Alymsys may cause a severe but uncommon neurological disorder that affects the nervous system. Symptoms may occur within a few hours after your first dose, but they might not be apparent for as long as a year after your treatment began. Contact your physician immediately if you experience: extreme weakness or fatigue; headache and confusion; vision problems; fainting; or seizures (blackouts or convulsions).

Alymsys may cause bleeding more frequently. Contact your doctor or seek medical attention in an emergency in the event that you suffer from:

  • Bleeding that is not unusual, easy to bruise, or any bleeding that won't stop;
  • Indications for bleeding inside your digestive tract, such as severe stomach pain and bloody or tarry stool, bleeding blood, coughing up blood, or vomit that looks similar to coffee grounds.
  • Symptoms of bleeding in the brain, such as sudden weakness or numbness, trouble speaking, a severe headache, or issues with balance or vision.

Some people who take Alymsys have created perforations (a tear or hole) or fistulas (an abnormal passageway) in the throat, stomach, intestines or lungs, gallbladder, bladder, kidney, or vagina. Consult your physician for urgent stomach pain or if you feel like you're in a coma whenever you eat or drink.

Make sure to contact your doctor if:

  • Slow wound healing
  • Skin inflammation (also known as open sores)
  • Menstrual period that is not occurring;
  • Kidney issues: swelling, less urination, and feeling tired or exhausted;
  • Indications of a blood clot: chest pain, a sudden and loud cough or breath shortness, nausea, coughing up blood and swelling, pain, or a warm sensation within one leg.
  • Heart issues: chest pressure or pain that is spreading to your shoulder or jaw, nausea, sweating, swelling, fast weight loss, or feeling tired of breath, or
  • Low white blood cell counts low white blood cell counts high fever, mouth sores, open sores in the skin, painful throat, cough

The treatment you receive for cancer could be delayed or discontinued permanently in the event of certain adverse consequences.

Common side effects of Alymsys can include:

  • Elevated blood pressure
  • Back pain, headache;
  • Eye dryness or wateryness;
  • Skin that is dry, flaky, or dry
  • Stuffy nose, runny nose, sneezing,
  • A change in taste.

This is not a comprehensive list of possible side effects, and other side effects could be present. Consult your physician to seek medical advice on the effects. It is possible to report any adverse allergic reactions or symptoms to FDA by calling 1-800-FDA-1088.


Alymsys may make it easier for you to get bleeding. Make sure to seek medical attention in an emergency in the event of bleeding that isn't stopping. It could also be a sign of internal bleeding within your body.

Prior to use this drug

There is a chance that you won't be able to take Alymsys when you are treated with other cancer drugs like doxorubicin, daunorubicin, or have had

  • Ovarian cancer that manifests as stomach pains that are severe or pelvic pain
  • The slow process of healing a wound or surgical incision
  • Surgery in the last four weeks (28 days);
  • You are planning to undergo surgery within the next four months (28 days). You are planning to have surgery within the next 4 weeks (28 days);
  • Vomiting blood or vomit that resembles coffee grounds.

Inform your doctor if you have ever suffered from:

  • Diabetes;
  • Heart conditions, like heart problems like heart attack, stroke, and blood clots, or a blood clotting disorder.
  • High blood pressure;
  • Bleeding issues  a perforation (a tear or hole) inside your oesophagus, stomach, or in your intestines
  • Kidney disease.

It could harm a baby who is not yet born. Avoid using it when you are pregnant. It is possible to require a pregnancy test in order to be sure you're not expecting. Utilise effective contraception with Alymsys for at least six months after the last dose. Inform your doctor immediately when you fall pregnant.Alymsys can cause women's ovaries to stop working properly. Ovarian failure symptoms include the absence of three or more menstrual cycles in a row. It could be more difficult to become pregnant when you are taking Alymsys or after receiving this treatment. Discuss with your physician regarding your specific risk.Don't breastfeed while taking this medication and for a minimum of six months after the last dose.

How to take Alymsys?

Alymsys is administered as an injection into the vein. Your healthcare provider will offer you the injection.Inform your doctor right away when you are feeling faint, dizzy, nauseated, sweaty, headaches, shortness of breath, or chest pain after the injection.Alymsys is typically administered every 2 or 3 weeks.Doses are determined by weight.Your dose may change if you gain or lose weight.You might require regular medical tests, and your cancer treatment may be delayed based on the results.

What happens if I miss the dose?

Consult your physician for further instructions in the event that you don't make an appointment to see your doctor for your Alymsys.

What happens if I overdose?

In a medical facility, an overdose could be taken care of quickly.

What should be avoided?

Avoid activities that increase the chance of injury or bleeding. Take extra care when cutting or brushing your teeth.

Interaction with other drugs

Discuss with your doctor all the other cancer treatments you're receiving.Other medications may interact with Alymsys. This includes prescription and non-prescription medications, vitamins, and herbal products. Inform your physician about any other medicines you take.




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