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Generic name: rabeprazole [ra-bep-ra-zole]
the brand names are: Aciphex, Aciphex sprinkle
Drug class: proton pump inhibitors

What is Aciphex?

Aciphex is an inhibitor of the proton pump, which reduces the amount of acid released by the stomach.

Aciphex is a short-term treatment used to manage symptoms associated with gastroesophageal reflux disorder (GERD) in adults and in children that are older than 1 year.

Aciphex is only used in adults for conditions that require high levels of stomach acid, like zollinger-ellison syndrome. It is also prescribed to adults to aid in healing duodenal ulcers as well as erosive reflux (damage to the esophagus due to stomach acid).

Aciphex could also be prescribed along with an antibiotic in order to avoid duodenal ulcers that are caused by the infection of helicobacter pylori (h. Pylori).


It is not recommended to use aciphex if you are sensitive to rabeprazole or other similar drugs like lansoprazole (Prevacid), esomeprazole (Nexium), omeprazole (prilosec, zegerid), or pantoprazole (Protonix).

Aciphex does not provide immediate relief of symptoms caused by heartburn.

Rabeprazole may cause kidney issues. Inform your physician if you have less urination than normal or have blood in the urine.

Diarrhea could be an indication of an outbreak of infection. Consult your physician for a consultation if you experience diarrhea that's a little fluid or contains blood.

Rabeprazole can result in the development of new symptoms or the worsening of lupus. Inform your physician if you are experiencing joint pain and inflammation of the skin on your cheeks or arms that gets worse in the sun.

Aciphex could increase the risk of a bone fracture occurring in your wrist, hip, or spine,

in particular when you are taking the drug long-term or more frequently than one each day.

Before You Take This Drug

Heartburn may be one of the early signs of a coronary attack. Seek medical attention immediately. If you are experiencing chest pain that extends into your shoulder or jaw and you are feeling anxious or lightheaded.

How to Take Aciphex?

Aciphex is generally taken only once a day. Make sure you follow all the instructions on the prescription label and review all drug guides and instructions. Make sure you use the medicine in the manner that is recommended.

Aciphex is intended for short-term use, just for 4 to 8 weeks. A doctor could suggest a different course of treatment if you require a longer recovery period.

Aciphex sprinkles shouldn't be offered to any child under one-year-old.

Drink this medication by drinking a glass full of water.

If you are taking this medication to treat ulcers in the duodenal tract, you should take it after eating. If you are taking Aciphex to treat ulcers that are caused by helicobacter pylori, you should consume the medication with meals. If you are taking it to treat some other reason, it is possible to consume the medication either by mouth or with food.

Be sure to read and adhere to any instructions for use that come with your medication. Consult your physician or pharmacist if you don't understand the instructions.

Take it whole. Swallow the tablet in its entirety, but do not crush, chew, or break it.

Avoid swallowing a delayed-release capsule (aciphex sprinkle) in its entirety. Then, open it up and pour the capsule with a spoonful of foods like applesauce, yogurt, or infant meals made with fruits or vegetables. The remedy is Pedialyte, apple juice, or infant formula. Take the medicine immediately without chewing. It is not a good idea to save it to use later.

This medication can alter the results of some medical tests. Be sure to inform any doctor treating your condition that you're using this medication.

Certain conditions can be treated using a combination of Aciphex and antibiotics. Follow all medication instructions.

Use your medication for the entire prescribed duration, even if symptoms begin to improve.

Contact your physician if symptoms don't improve or if they get worse when you use Aciphex.

Keep at room temperature, free of heat and moisture.

What Happens if I Miss a Dose?

You should take your medicine as quickly as possible; however, do not take the missed dose when it's almost time to get the next dose. Don't take more than two doses simultaneously.

What Happens if I Overdose?

For medical emergencies, seek emergency treatment or dial toll-free the poison help line at 1-800-222-1222.

What Should be Avoided?

This medication can trigger diarrhea, which could indicate an infection that has recurred. If you experience diarrhea that's watery or bloody, consult your doctor prior to using an anti-diarrhea m medication.

Side effects of Aciphex

See a doctor immediately. Get medical attention immediately if you show signs of an allergic response. Aciphex: hives, breathing difficulties, or swelling of your lips, face, and tongue.

It is not recommended to make use of Aciphex in the event that you are sensitive to rabeprazole.

Mild effects

  • If you are also taking any other medication that has the ingredient rilpivirine (edurant, Complera, Juluca, Odefsey)

  • If you have breathing issues, kidney problems, or an extreme allergic reaction following having taken rabeprazole previously

  • If you're also allergic to medications like rabeprazole, for example, esomeprazole, lansoprazole, omeprazole, or pantoprazole, nexium, prevacid, prevacid, protonix, and others

Adverse side effects

  • The liver

  • Osteoporosis or low bone mineral density (osteopenia)

  • Lupus (an autoimmune disorder)

  • The magnesium levels are low in the blood of your patient

There is a higher chance that you will break a bone in your hip or wrist in the event you take an inhibitor of the proton pump long-term or more often than one every day


Talk with your doctor about ways to ensure your bones are healthy.

 don't give this medication to children without medical guidance. Certain forms and dosages of rabeprazole should never be administered to children younger than 12 years old.

Interaction with Other Drugs

Inform your doctor about the medicines you are taking currently. Numerous drugs can interact with rabeprazole, specifically:

  • An antibiotic like clarithromycin or amoxicillin;

  • Digoxin;

  • Diuretic, also known as a "water pill";

  • Methotrexate;

  • Warfarin (Coumadin, Jantoven).

This list isn't complete, and there are many other drugs that can interfere with the drug rabeprazole. This includes over-the-counter and prescription medications, vitamins, and herbal products. There are many possible interactions between drugs, which are listed here.



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