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Abacavir and Lamivudine Tablets

Generic name: Abacavir and Lamivudine Tablets

Name of Brands: Epzicom

Format for Dosage: Tablet

Drug classification: Antiretroviral Agent, Nucleoside Reverse Transcriptase Inhibitor (NRTI) Combination

What are Abacavir as well as Lamivudine Tablets?

Abacavir and Lamivudine Tablets, marketed under the brand name Epzicom a fixed dose combination medicine used in treating HIV (Human Immunodeficiency Virus) infection. The tablets consist of a mixture of lamivudine and Abacavir, which belong to the group of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs). Together, they hinder the replication of viruses.


  • Hypersensitivity that is severe and possibly fatal reactions have been reported with lamivudine or abacavir use. Before starting treatment, a genetic test is recommended to determine if a person is susceptible to this reaction.
  • Stop the medication as soon as possible and refrain from re-initiating the medication if a hypersensitivity reaction has been suspected.

Before You Start This Medicine:

Before starting Abacavir and Lamivudine Tablets, inform your doctor about any medical issues you may have, which include kidney disease, liver disease, or a history of drug-related allergies.

How to Take Abacavir and Lamivudine Tablets?

  • Abacavir and Lamivudine tablets should be consumed orally as a tablet every day and without or with food if directed by your physician.
  • Follow the doctor's advice on Dosage as well as timing.

Information on Dosage

The dose for Abacavir or Lamivudine Tablets is determined by your doctor following factors like your weight and medical history as well as other medications you might be taking.

What Happens If I Miss a Dose?

If you miss the dose, you should do it as soon as you remember. If it's time to take your next dose, don't take the missed dose and follow your regular dosing schedule.

What Happens If I Overdose?

If you suspect an overdose, get medical help immediately. Overdose symptoms can include nausea, vomiting, fatigue, and difficulty sleeping.

What Should be Avoided?

  • Please do not stop taking Abacavir and Lamivudine Tablets without consulting your physician, as it could result in a declining efficiency of HIV treatment.
  • Please do not drink alcohol when taking this medication because it could increase the risk of adverse side effects.

Acute Side Effects Abacavir, as well as Lamivudine Tablets Moderate Effects Abacavir and Lamivudine tablets, are commonly used for mild adverse effects, which could include:

  • Nausea
  • Headache
  • Diarrhea
  • Fatigue

Adverse effects: Serious adverse effects may be a result of:

  • Hypersensitivity reaction (fever and nausea, rash abdominal pain)
  • Lactic acidosis (unusual muscle pain, trouble breathing, and stomach pain)
  • Liver problems (jaundice, dark urine, abdominal pain)

Interactions with Other Drugs:

Inform your doctor of all your medications, such as over-the-counter and herbal supplements. Abacavir or Lamivudine Tablets could be incompatible with other medications, specifically those that affect the kidneys or the liver.