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60 mg Xpovio twice-weekly

Generic name: selinexor [SEL-i-NEX-or]
Brand names: Xpovio 100 mg once-weekly; Xpovio 40 mg once-weekly; Xpovio 40 mg twice-weekly; Xpovio 60 mg once-weekly; Xpovio 60 mg twice-weekly; Xpovio 80 mg once-weekly; Xpovio 80 mg twice-weekly.
The class of drug: miscellaneous antineoplastics

What is Xpovio 60 mg?

The Xpovio capsule, 60 mg once a week, is taken in conjunction with bortezomib or dexamethasone to treat multiple myeloma in adults.Xpovio 60 mg twice weekly is also taken by adults to treat certain kinds of lymphoma that are diffuse and large.The Xpovio 60 mg dose twice weekly is administered after other drugs have failed to have any effect or have ended their effectiveness.

Xpovio 60 mg twice weekly has been approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, certain patients have responded to Xpovio 60 mg twice weekly; however, further research is required.Xpovio 60 mg twice a week may also be prescribed for other purposes that are not mentioned in this guide.60 mg twice weekly Xpovio adverse reactions

See a doctor immediately. If you are experiencing symptoms that are warning signs of an allergic response, such as difficulty breathing, hives, and swelling of your lips, face, and tongue,Xpovio 60 mg twice a week could cause fatal or serious adverse effects. Certain side effects might not manifest until you've taken this medication for a few days or weeks.Xpovio 60 mg twice a week can result in serious adverse side effects. Contact your physician immediately. If you suffer from:

  • Blurred vision blurred vision, tunnel vision, eye pain, or seeing halos around light sources;
  • Severe ongoing nausea, vomiting, or diarrhoea;
  • Insomnia that prevents your from eating, and ultimately leads to an increase in weight gain;
  • Dizziness, confusion, fainting, or changes in mental state;
  • Signs that are indicative of sepsis signs of sepsis symptoms of sepsis include fever or chills. Extreme fatigue and rapid heartbeats quick breathing, and feeling sick;
  • Indications of symptoms of fever symptoms of infection such as chills symptoms of flu, such as chills and fever manifestations, cough with mucus, throat and mouth ulcers, feeling breathless and tingling, or a painful blistering skin rash on the other part of the body,
  • Low sodium levels: headache low sodium level, slurred speech, extreme weakness, vomiting, loss of coordination, feeling unstable

The treatment you receive might be delayed or removed if you suffer from specific adverse consequences.

Common adverse consequences associated with Xpovio 60 mg twice a week are:

  • Double vision; blurred or double vision sensitive to light or glare
  • Tiredness;
  • Tingling, numbness, and burning sensations in your feet or hands;
  • Anaemia, bleeding, bruising, or bleeding;
  • Higher blood sugar levels
  • Infections, fever, cold, or symptoms of the flu;
  • Shifts in mineral and sodium levels;
  • Irregular kidney function or liver tests;
  • Nausea and vomiting, as well as nausea, vomiting,
  • Diarrhoea, constipation;
  • Weight loss;
  • Breath shortness.

It's not a comprehensive list of the possible consequences, but other reactions could be experienced.Contact your doctor for advice regarding medical effects. You can report symptoms to the FDA at 1-800-FDA-1088.

Similar or related drugs

Darzalex, Blenrep, Tecvayli, Carvykti, prednisone, rituximab, and cyclophosphamide

Warnings

It is possible to contract infections more frequently, even deadly or life-threatening infections. Call your doctor if you are suffering from a fever, chills, flu-like symptoms, chills or mouth ulcers, a cough, or breathing problems.Xpovio 60 mg twice a week may also result in lower levels of platelets in the blood. Contact your physician immediately in the event of unusual bruising or bleeding.

Before you take this drug

Inform your doctor if you were ever diagnosed with:

  • Cataracts;
  • Bleeding problems,
  • Active or recent infections.

It is possible that you will need to take a pregnancy test that is negative prior to beginning this treatment.Women and men who are taking Xpovio 60 mg twice a week must use effective birth control in order to prevent the birth of a baby. Xpovio 60 mg twice a week can harm an unborn child when the father or mother is taking this medication.Continue using the birth control for at least one week following your last dose. Inform your doctor immediately in the event of a pregnancy occurring when one of the parents or father is taking Xpovio 60 mg twice a week.

This medicine can impact fertility (the ability to have children) in both males and women. But it is crucial to take birth control in order to avoid pregnancy since Xpovio 60 mg twice weekly could harm a baby who is not yet born.Avoid breastfeeding while taking this medication and for at least a week after the last dose.The use of this product is prohibited by anyone younger than 18 years old.

How to take Xpovio 60 mg?

The doctor will run tests to ensure that Xpovio 60 mg twice a week is the best treatment for you.Follow the instructions on the prescription label and review all medication guides and instruction sheets. The doctor might alter your dosage. Make sure you take the medicine precisely as directed.Xpovio 60 mg twice weekly is typically taken on certain days and is usually taken once or twice each week. Follow the instructions of your physician carefully regarding the best time and method to take this medicine along with dexamethasone or bortezomib.Your doctor will decide on the duration of treatment by using Xpovio 60 mg twice weekly and dexamethasone.

Use Xpovio 60 mg two times a week with an entire drink of fluid. Suck the tablet whole, but avoid crushing, chewing, or breaking the tablet.If you experience vomiting shortly after having taken Xpovio 60 mg twice weekly, don't take a second dose. Do your next dose according to when you are scheduled to take it.You might also be prescribed additional medications to treat nausea or vomiting as well as infections. Take these medications for the duration your doctor prescribes.

There is a chance that you will contract infections more often, or even fatal or severe infections. You'll require frequent medical tests. There is a possibility of needing an injection when your platelets in your blood become low.The sodium levels in your blood are required to be checked. If they are way too low, your physician might prescribe salt pills or intravenous (IV) fluids to prevent your body from becoming dehydrated.

HTML0 Get plenty of fluids to avoid dehydration. consume enough calories to avoid losing weight.The Xpovio 60 mg dose twice weekly may affect your appetite or capacity to consume. The weight of your body will be measured prior to and during the treatment in order to ensure that you don't lose weight while taking this medication.Make sure the tablet is kept at room temperature, and away from humidity and heat. Store each Xpovio 60 mg tablet twice weekly inside the pack of blisters until you are in a position to take your dosage.

What happens if I miss a dose?

Don't miss the dose you missed, and take your next dose at the normal time. Don't use two doses at the same time.

What happens if I overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

What should be avoided?

Avoid driving and other hazardous activities until you are aware of the effects that Xpovio 60 mg twice weekly can have on you. The way you react could be impaired.

Interaction with other drugs

Other medications can influence Xpovio 60 mg twice weekly, such as prescription and over-the-counter medications, vitamins, and products made from herbs. Discuss with your physician all other medications you take.

 

DRUG STATUS

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Prescription only

Pregnancy & Lactation

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