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Zylet (ophthalmic)

Generic name: loteprednol and tobramycin (ophthalmic) [LOVE-the-PRED-nol-and-TOE-bra-MYE-sin-off-THE-mick]
The brand name is Zylet.
The class of drug: ophthalmic steroids with anti-infectives

What are Loteprednol and tobramycin?

Loteprednol and tobramycin ophthalmic (for your eyes) is an antibiotic and steroid drug that treats eye inflammation due to allergies or itching (herpes zoster) and acute acne, iritis, eye injuries, uveitis, chemical burns, radiation, or any other condition.This medicine is administered in cases where there is a high chance of an infection caused by bacteria within and around the eyes.

Tobramycin and loteprednol ophthalmic can also be used to treat conditions that aren't listed in this guide.See a doctor immediately. If you are experiencing symptoms that indicate an allergic reaction, such as hives, difficulty breathing, and swelling of your lips, face, and throat,

Zylet could cause severe adverse reactions. Consult your physician immediately in the event that you experience:

  • Extreme burning or stinging sensations when applying eye drops.
  • Blurred vision blurred vision, tunnel vision, spotting halos around light sources;
  • Pain behind your eyes, sudden vision changes;
  • Slow healing after eye surgery;
  • Symptoms of signs of eye pain—redness or extreme discomfort, swelling, or drainage.

Common negative side effects of Zylet could include:

  • Blurred vision
  • Minor stinging or burning.

There isn't an exhaustive list of the possible consequences, but other effects might occur. Ask your physician for medical advice about adverse effects. It is possible to report any adverse reaction to FDA by calling 1-800-FDA-1088.


This medicine is recommended if you are suffering from an ocular infection that is fungal or an infection that is viral around your eyes (including herpes simplex).

Before you take this drug

This medication is recommended if you have an allergy to tobramycin or loteprednol or if you suffer from an infection of the fungal or viral kind around your eyes (including herpes simplex).

Speak to your doctor if you were ever diagnosed with:

  • Glaucoma;
  • Cataracts, or require surgery for cataracts.

It isn't clear if this medication will cause harm to a baby who is not yet born. Inform your doctor if you are expecting.

It might not be safe to breastfeed while using this medication. Consult your physician about any potential risks.

How to take Zylet?

Follow the directions on your prescription label, and review all medication guides and instructions sheets. Follow the medication exactly as prescribed.

Avoid using the lenses while wearing soft ones. The ingredient that preserves this medicine can permanently stain your lenses. Make sure to take the medicine for at least 15 minutes prior to inserting your contact lenses.Clean your hands before applying eye medications.Make sure to shake the eye drops thoroughly before every use.

To apply this medication, tilt your head slightly back and then pull the lower eyelid, creating an eyelid pocket. Then, hold the dropper in front of your eye and put a drop in the pocket. After that, shut your eyes for one to two minutes.Only use the amount of drops that your doctor has recommended.

Don't touch the tip of your eyedropper or put the dropper directly onto your eyes. A dropper that is contaminated could cause an eye infection, which could cause serious vision problems.If you are taking this medication for longer than 10 consecutive days, it is possible that you will require frequent eye tests to determine the pressure in your eyes.

Consult your physician. If your symptoms don't improve after two treatments,Do not stop taking this medicine abruptly. Follow your doctor's advice on increasing your dosage.The medicine should be stored in an upright place at room temperature. Don't freeze it.

Do I be concerned if I miss a dose?

Utilize the medicine as soon as you can; however, do not miss any missed doses if you are nearing the time to take the next dose. Don't take two doses in one go.

What will happen if I take excessively?

An overdose of loteprednol as well as tobramycin is unlikely to pose any danger. You should seek medical attention in an emergency or contact the Poison Helpline at 1-800-222-1222 in the event that someone has swallowed the drug accidentally.

What should be avoided?

Don't share this medication with anyone else, even if they share similar symptoms to yours.

Interaction with other drugs

Eye medicine is unlikely to be affected by other medicines that you are taking. However, many medications can interact with each other. Be sure to inform your healthcare professionals about all medicines you are taking, such as medications that are prescribed and available over the counter, vitamins, and herbal remedies.