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Generic name: [dex-troe-meth-OR-fan, gwye-FEN-e-sin, fen-il-EFF-rin]dextromethorphan, guaifenesin, and phenylephrine
Names of brands: Broncotron Ped, Children’s Giltuss Cough and Cold, Deconex DMX, Desgen DM (Phenylephrine), Desgen Pediatric, etc. List all 39 names.
The class of drug: upper respiratory combinations

What is Zotex-EX?

Dextromethorphan is a cough suppressant that influences the brain's neurons to stimulate the cough reflex. Guaifenesin can be described as an expectorant that eases congestion in the throat and chest. Phenylephrine Phenylephrine is a decongestant that shrinks blood vessels within the nasal passages.

Zotex-EX can be described as an all-in-one medicine that is used to treat congestion, cough, and chest congestion that is caused by allergies, commonly-assisted colds, and an illness called the flu.Zotex-EX is not a treatment for coughs due to cigarettes, asthma, or emphysema.

There are a variety of kinds and brands of this medication available. Not all brands are included in this leaflet.Zotex-EX can also be used to treat conditions that are not mentioned in this guide.

Side Effects of Zotex-EX

See a doctor immediately. Get medical attention immediately if you notice symptoms warning signs of an allergic response like hives, trouble breathing, and swelling of your lips, tongue, throat, or face.

This medication could cause severe adverse reactions. Stop taking this medicine and contact your doctor immediately if you suffer from:

  • Very little or no urine;
  • Rapid or slow heartbeats;
  • Confusion, dizziness, feeling unsteady;
  • Nervousness; sleep problems (insomnia);
  • Severe nausea or vomiting;
  • A severe headache, blurred vision, the pounding of your neck or in your ears;
  • Breath and/or
  • Strange change in behavior or mood.

Common side effects of Zotex EX include:

  • Diarrhea, constipation;
  • Dizziness, drowsiness;
  • Sleep problems (insomnia);
  • Experiencing anxiety, agitation, or anger.

It's not a comprehensive listing of all possible adverse consequences, but other reactions could be experienced. Ask your doctor medical advice about adverse reactions. It is possible to report any adverse reaction to FDA by calling 1-800-FDA-1088.


Don't take this medicine if you've had an MAO inhibitor within the past 14 days, for example, linezolid, isocarboxazid, rasagiline, selegiline, or tranylcypromine.

Before you take this drug

This medication is for you if you have an allergy to dextromethorphan, guaifenesin, or the hormone phenylephrine.

Don't take this medication if you've had an MAO inhibitor within the last 14 days. A potentially dangerous interaction between drugs can occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Ask your doctor or pharmacist to determine if this medication is suitable for use if you are:

  • The heart condition, high blood pressure;
  • Diabetes;
  • A thyroid disorder
  • Problems with urination;
  • Glaucoma;
  • Epilepsy or any other seizures;
  • Pheochromocytoma (an adrenal gland tumor);
  • Mucusy cough or cough that is caused by emphysema as well as chronic bronchitis.

This medication may contain phenylalanine. Be sure to check the label of the medication if you suffer from the condition known as phenylketonuria (PKU).

Consult a physician before using this medicine if you are breastfeeding or pregnant.

How to take Zotex EX?

Follow the directions on the label or as recommended by your physician. Cough medication is meant for short-term use only until symptoms improve.

Follow the instructions on the medication label regarding administering cold or cough medication to children. Don't use the medication solely to induce sleepiness in a child. Death can occur due to the use of cold or cough medications in infants and young children.Do not chew, crush, or break the extended-release tablet. Suck it up whole.

Make sure to measure the liquid medicine with care. Make use of the dosing syringe supplied or a dosage measuring device (not an ordinary spoon).Drink more fluids to alleviate congestion and lubricate your throat while taking this medication.Consult your physician if symptoms don't improve after 7 days or if you suffer from an itch, high fever, rash, or headaches.

If you are in need of surgical intervention or other medical examinations, inform the doctor or surgeon prior to the time of your appointment if you took this medication within the last few days.Storage at room temperature, far from heat and moisture. Make sure that you do not allow liquid medicines to become frozen.

What happens if I miss a dose?

Because cough or cold medicine is taken when necessary, you may not be on a regular dosing schedule. Do not miss any doses when it's time to take the next dose. Do not take two doses at once.

What happens if I overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

What should be avoided?

Avoid driving or engaging in hazardous activities until you are aware of the effects of this medication on your body. The way you react could be impaired.Drinking alcohol can trigger the effects of this medication.

Consult a physician or pharmacist prior to using any other cold or cough medicines that contain similar components.

Interaction with other drugs

Avoid taking Zotex-EX along with other medications that may result in drowsiness or slow breathing (such as opioids as well as a muscle relaxer or medicines to treat anxiety as well as seizures). Talk to your doctor or pharmacist prior to taking any other medications, such as prescription and over-the-counter medicines, vitamins, and herbal remedies. There are many possible interactions between drugs that are covered in this drug guide.