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Z-tuss DM

Generic name: [dex-troe-meth-OR-fan, gwye-FEN-e-sin, fen-il-EFF-rin]dextromethorphan, guaifenesin, and phenylephrine
Names of brands: Broncotron Ped, Children’s Giltuss Cold and Cough, Deconex DMX, Desgen DM (Phenylephrine), Desgen Pediatric,… Display all 39 names
Classification of drugs: upper respiratory combinations

What is Z-tuss DM?

Dextromethorphan is a cough suppressant that alters the neuronal signals that stimulate the cough reflex. Guaifenesin can be described as an expectorant, which eases congestion in the throat and chest. Phenylephrine can be described as a decongestant that shrinks blood vessels in the nasal passages.

Z-tuss DM is a mixture medicine that treats congestion, cough, and chest congestion caused by allergies, a commonly-assisted cold, and an illness called the flu.Z-tuss DM does not treat coughs caused by cigarettes, asthma, or the condition known as emphysema.

There are a variety of varieties and brands of this medication available. Some brands are not mentioned in this leaflet.Z-tuss DM can be used for other purposes not mentioned in this guide to medication.

Side Effects of Z-tuss DM

Contact a medical professional immediately. If you are experiencing symptoms that indicate an allergic reaction, such as hives, difficulty breathing, and swelling of your lips, face, and tongue,

This medication could cause severe adverse reactions. Take this medicine off and contact your doctor immediately if you experience:

  • Minimal or no urination
  • Heartbeats that are slow or fast;
  • Confusion, dizziness, feeling unsteady;
  • Nervousness; sleep problems (insomnia);
  • Severe nausea or vomiting;
  • A severe headache severe headache, blurred vision, or the pounding of your neck or ear;
  • Breath and/or
  • Strange shifts in behavior or mood.

Common adverse consequences of Z-tuss DM can include:

  • Diarrhea, constipation;
  • Dizziness, drowsiness;
  • Sleep problems (insomnia);
  • Being anxious, restless, or angry.

This is not a comprehensive list of possible side effects, and others could happen. Consult your physician for advice regarding medical adverse effects. You can report any symptoms to the FDA at 1-800-FDA-1088.

Related drugs

Bromfed DM, brompheniramine, dextromethorphan, and pseudoephedrine; Vicks Dayquil Cold & Flu Relief; Mucinex D; and Promethazine VC with Codeine


Do not take this medication if you've had an MAO inhibitor within the last 14 days, for example, isocarboxazid and linezolid, as well as phenelzin, rasagiline, selegiline, and tranylcypromine.

Before you take this drug

It is not recommended to use this medication if you have an allergy to dextromethorphan, guaifenesin, or the hormone phenylephrine.

Do not take this medicine. If you've previously had an MAO inhibitor within the last 14 days. A potentially dangerous interaction between drugs can occur. MAO inhibitors are isocarboxazid, rasagiline, linezolid, phenelzine, selegiline, tranylcypromine, and selegiline.

Consult a pharmacist or doctor for a recommendation on whether this medicine is safe to use if:

  • Heart disease, high blood pressure;
  • Diabetes;
  • An thyroid disorder;
  • Urination issues;
  • Glaucoma;
  • Epilepsy or a different type of seizure;
  • Pheochromocytoma (an adrenal gland tumor);
  • Mucusy cough or a cough that is caused by emphysema or chronic bronchitis.

The medicine could contain phenylalanine. Be sure to check the medication label if you suffer from phenylketonuria (PKU).

Consult a physician before taking this medication if you are nursing or pregnant.

How to take Z-Tuss DM?

Take it exactly as indicated on the label or as directed by your physician. The cold or cough medicines are meant for short-term use only until symptoms improve.

Always adhere to the directions on the medication label regarding the administration of cold or cough medicine to children. Don't take the medicine solely to help a child fall asleep. Death can occur due to the use of cold or cough medicine in children who are very young.

Don't crush, chew, or break the extended-release tablet. Take it in whole.Take care when measuring liquid medicines. Use the dosing syringe supplied or a dose-measuring device (not an ordinary spoon).

Drink more fluids to alleviate congestion and lubricate your throat when you are taking this medicine.Contact your physician if your symptoms don't get better after 7 days or if you experience symptoms such as a high fever, rash, or headaches.

If you require an operation or tests for medical reasons, notify your doctor or surgeon before the appointment time if you have taken this medicine in the last few days.Keep the medicine at room temperature, free of heat and moisture. Make sure that you do not allow liquid medicines to become frozen.

What happens if I miss a dose?

Because cold or cough medication is prescribed when it's necessary, you may not be following a dose schedule. Don't miss any missed doses in the event that it's nearing the time to take the next dose. Do not take two doses at once.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line at 1-800-222-1222.

What should be avoided?

Avoid driving or engaging in hazardous activities until you are aware of the effects this medication will have on your body. The way you react could be impaired.

Alcohol consumption can cause an increase in certain adverse effects associated with this medication.Consult a physician or pharmacist prior to using any other cold or cough medicines that contain similar components.

Interaction with other drugs

Beware of using Z-tuss DM alongside other medications that can cause drowsiness or slow breathing (such as opioids, muscle relaxers, or medications to treat anxiety and seizures). Talk to your doctor or pharmacist prior to using any other medications, such as prescription and over-the-counter medicines, vitamins, and herbal remedies. Some interactions with drugs are included in this guide to medication.