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Generic name: dextromethorphan, guaifenesin, and phenylephrine [dex-troe-meth-OR-fan, gwye-FEN-e-sin, fen-il-EFF-rin]
Names of brands: Broncotron Ped, Children’s Giltuss Cough and Cold, Deconex DMX, Desgen DM (Phenylephrine), Desgen Pediatric,
Classification of drugs: upper respiratory combinations

What is Supress-DX?

Dextromethorphan is a cough suppressant that alters the neuronal signals that stimulate the cough reflex. Guaifenesin can act as an expectorant, which eases congestion in the throat and chest. Phenylephrine can be described as an anti-congestant that reduces blood vessels within the nasal passages.Supress-DX is a mixture medicine to treat congestion, cough, and chest congestion that is caused by allergies, commonly-assisted colds, and an illness called the flu.

Supress-DX cannot help with a cough due to cigarettes, asthma, or the condition known as emphysema. There are a variety of kinds and brands of this medicine that are available. There are not all the brands mentioned in this leaflet. that are not covered in this guideline.

Side Effects

Contact a medical professional immediately. If you are experiencing symptoms that are warning signs of an allergic response, like hives, trouble breathing, or swelling of your lips, face, or tongue,

This medication could cause severe adverse effects. Take this medicine off and consult your physician immediately if you suffer from:

  • Very little or no urine;
  • Heartbeats that are slow or fast;
  • Confusion, dizziness, feeling unsteady;
  • Nervousness; sleep problems (insomnia);
  • Severe nausea or vomiting;
  • A severe headache severe headache, blurred vision, or pain in your neck or in your ears;
  • Breath and/or
  • Unexpected change in behaviour or mood.

Common adverse effects of Supress DX can include:

  • Diarrhoea,
  • Constipation;
  • Dizziness, drowsiness;
  • Sleep problems (insomnia); or
  • Experiencing anxiety, agitation, or anger.

This isn't a complete list of all the side effects. Other effects may also be present. Contact your physician to seek medical advice on the effects. You can report any symptoms to the FDA at 1-800-FDA-1088.

Related drugs

Bromfed DM, brompheniramine, dextromethorphan, and pseudoephedrine; Vicks Dayquil Cold & Flu Relief; Mucinex D; and Promethazine VC with Codeine


Do not take this medication if you've taken an MAO inhibitor within the last 14 days, for example, isocarboxazid, linezolid, rasagiline, selegiline, or tranylcypromine.

Before you start taking this medicine

It is not recommended to use this medication if you have an allergy to guaifenesin, dextromethorphan, or the hormone phenylephrine.

Don't take this medication if you've used an MAO inhibitor within the last 14 days. A drug interaction that is dangerous may occur. MAO inhibitors are isocarboxazid rasagiline, phenelzine, linezolid selegiline, tranylcypromine, and selegiline.

Consult a pharmacist or doctor to determine if this medication is safe to use if:

  • The heart condition, high blood pressure;
  • Diabetes;
  • A thyroid disorder
  • Problems with urination;
  • Glaucoma;
  • Epilepsy or another seizure;
  • Pheochromocytoma (an adrenal gland tumor); or
  • Cough that is mucus-filled or a cough that is due to emphysema, as well as chronic bronchitis.

This medication may contain phenylalanine. Make sure to read the label on the medicine if you suffer from phenylketonuria (PKU).

What is the best way to take Supress DX?

Follow the directions on the label or as recommended by your physician. The cold or cough medication is meant for short-term use only until symptoms improve.

Follow the instructions on the label of the medicine about administering cold or cough medication to children. Don't use the medication solely to help a child fall asleep. Death can occur through the misapplication of cough or cold medicine in children who are very young.

Don't crush, chew, or break the extended-release tablets. Suck it up whole.

Take care when measuring liquid medicines. Use the syringe for dosing or a dosage-measuring device (not the kitchen spoon).

Drink plenty of fluids to ease congestion and smooth your throat while taking this medication.

Consult your physician if symptoms don't improve after 7 days or if you suffer from symptoms such as a temperature, rash, or headaches.

If you require surgical intervention or tests for medical reasons, inform the doctor or surgeon before the appointment time if you have taken this medication in the last few days.

Storage at room temperature, far from heat and moisture. Make sure that you do not allow the medicine to cool down.

What happens if I miss a dose?

Since cold or cough medication is prescribed when it's needed, you might not be following a regular dosing regimen. Do not miss any doses in the event that it's nearing the time to get the next dose. Don't take two doses at once.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact the Poison Help line at 1-800-222-1222.

What should be avoided?

Avoid driving or engaging in hazardous activities until you are aware of the effects this medicine has on your body. Your reaction could be affected. Drinking alcohol can trigger the effects of this medication. Consult a physician or pharmacist prior to taking other cough or cold medications that may have similar components.

Interaction with other drugs

Beware of using Supress-DX alongside other medications that can result in drowsiness or slow breathing (such as opioids as well as a muscle relaxer or medications used to manage anxiety as well as seizures). Consult a physician or pharmacist prior to using any other medication, which includes prescription and non-prescription medicines, vitamins, and herbal supplements. There are many possible interactions between drugs that are included in this guide to medication.