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Stimufend

Generic name: Pegfilgrastim (pronounced PEG-filgras-tim)

Brand names include: Fulphila, Fylnetra, Neulasta, Neulasta Onpro Kit, and Nyvepria. To see all 8 brands
Drug class: colony-stimulating factors

What is Stimufend?

Stimufend helps to prevent neutropenia, a condition caused by chemotherapy.

Stimufend, a type of protein, stimulates white blood cell growth that helps your body fight infections. Stimufend can be used in other ways not mentioned in this medication guide.

Side effects of Stimufend

If you experience any of the following symptoms, seek emergency medical attention: hives; skin rash; sweating; warmth or tingly sensation; dizziness; rapid heartbeats; difficulty breathing; wheezing; swelling on your face, lips, or tongue; or throat.

Capillary Leak Syndrome is an uncommon yet potentially severe side effect of pegfilgrastim. If any of the following symptoms arise while taking this drug, seek medical assistance immediately:

Stimufend may cause serious side effects. If you experience:

  • A sudden and severe pain that spreads from your upper left stomach to your shoulder
  • Sudden and severe pain in the chest, abdomen, or back
  • You may experience severe pain in any part of your body.
  • Fever, tiredness;
  • Rapid breathing;
  • Are You Suffering From Easy Bruises, Unusual Bleeding or Purple/Red Patches Under the Skin?
  • A hard lump or bruise where the injection was made
  • Kidney problems: little or no urine, dark urine or pink urine, swelling of the face or legs.

If you experience certain side effects, your cancer treatment may be permanently stopped or delayed.

Stimufend side effects may include:

  • Bone pain
  • Your arms or legs may be experiencing pain.

There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.

Warnings

Please read all the instructions on the label or package of your medication. Inform your healthcare provider about your medical conditions, allergies, and medicines.

Before you take this drug

Stimufend should not be used if you have an allergy to Stimufend, Filgrastim, or Neupogen.

Inform your physician of any of the following issues:

  • Sickle cell disorder;
  • Kidney disease
  • Acute Myeloid Leukemia
  • Radiation treatment
  • Myelodysplastic Syndrome
  • A latex allergy.

You could develop a blood disease or cancer (leukemia) after treatment with Fullphila or radiation, with or without chemotherapy, for breast cancer or lung carcinoma. You should ask your doctor for more information.

How to take a Stimufend?

Read all instructions or guides that come with your medication and follow all directions. Follow the instructions on your prescription label. Stimufend shouldn't be taken within 24 hours of receiving chemotherapy or 14 days prior to it. Stimufend can be injected into the skin. Your healthcare provider should teach you how to take the medication correctly.

Please read and heed all directions that accompany your medication, if there are any. If there are any queries, ask your physician or pharmacist. Only prepare an injection when it is time to give it. If the medicine appears cloudy or discolored or contains particles, do not use it. For new medicine, call your pharmacist. You may need to have your blood tested frequently.

Do not use the prefilled syringe to measure the correct dose of Stimufend for a child weighing less than 99 lbs (45 kg). Your doctor may need to perform medical tests in order to determine the length of treatment you should receive with Stimufend. Keep the prefilled syringe protected from light in its original packaging in the fridge. Do not shake or freeze. Before injecting the dose, remove the syringe from the refrigerator. Let it sit at room temperature for between 15 and 30 minutes. Thaw a frozen syringe in the refrigerator. Use only syringes that have not been frozen before.

Use a syringe that has been at room temperature for longer than 48 hours. Use a syringe of Fylnetra or Stimufend that has been at room temperature for longer than 72 hours. Use a Ziextenzo needle that has been at room temperature for longer than five days. The Neulasta Injector Onpro is a device that you place on your skin to deliver the Stimufend dosage at a certain time. Wear the device for at least 27 hours to receive the first dose. The dose will be released slowly from the device over a period of 45 minutes.

Refrigerate Neulasta Onpro until you're ready to use it. Do not use a Neulasta Onpro that has been out of the refrigerator for more than 12 hours. Use a prefilled Nyvepria syringe if it has been out of the fridge for more than 15 days. You or your caregiver should check Neulasta Onpro to ensure it is functioning properly.

Each Onpro injector or prefilled syringe is only for one-time use. After one use, throw it out, even if the medicine is still inside. Only use a needle or syringe once, and then store them in a "sharps container" that is puncture-proof. Be certain to comply with local or state regulations on how to safely dispose of the container. Keep the container out of the reach of pets and children.

What happens if I miss the dose?

If you missed an injection or have any problems with the Neulasta Onpro, call your doctor.

What happens if I overdose?

Call 1-800-222-1222 for poison help or seek immediate medical attention. Overdose symptoms can include pain in the bones, difficulty breathing, shortness of breath when lying down, foamy mucus from a cough, and cold skin.

What should be avoided?

While wearing Neulasta Onpro, avoid driving, operating machinery, or traveling while wearing the device.

Interaction with other drug

Stimufend may be affected by other drugs, such as vitamins and herbal remedies.Inform your physician of any and all medications you are currently taking or any that you discontinue or start using.