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Solifenacin

Generic Name: Solifenacin GSol-ee-FENa-sin
Brand Names: VESIcare, VESIcare LS
Dosage Forms: (1 mg/mL), oral tablet (10 mg; 5 mg),Oral suspension
Classification of Drugs: Urinary antispasmodics

What is Solifenacin?

Solifenacin helps treat the symptoms associated with excessive bladder activity, including frequent or rapid urination or urinary incontinence (urine loss).Oral suspension of Solifenacin (liquid), Vesicare LS, is used to treat bladder overactivity due to a neurologic condition (such as MS or spinal cord injury) in children who are at least two years old when other medications cannot be employed or haven't worked.

Solifenacin is also employed for other purposes that are not covered in this guideline for medication.

Side effects of Solifenacin

Contact emergency medical assistance when you are experiencing symptoms warning signs of an allergic response (hives, breathing difficulties, or swelling of your throat or face) or a severe reaction to your skin (fever, sore throat, eye burning, irritation, and an ailment that is purple or red and blisters and peels).

Solifenacin may cause serious side effects. Stop taking solifenacin and contact your physician immediately. If you suffer from:

  • Extreme stomach pain as well as constipation for three or more days;
  • Burning or pain after you urinate;
  • Headache, confusion, drowsiness, and hallucinations;
  • Vision changes and pain or seeing halos in light sources;
  • Minimal or no urine, burning, or pain when you pee;
  • Dehydration symptoms: tiredness, dizziness, feeling thirsty, less sweating, dry and hot skin,
  • High potassium levels high potassium level; nausea; weak and tingling sensations chest discomfort, irregular heartbeats decreased movement.

Common side effects of Solifenacin can include:

  • Blurred vision
  • Dry mouth Dry eyes;
  • Painful urination;
  • Constipation
  • Heat Strike: decreased sweating, sweaty skin, dizziness, nausea, fatigue, and feeling hot

It's not a comprehensive listing of all negative results. Other scenarios could occur. Talk to your doctor for medical advice about adverse effects. If you have any concerns, report them to the FDA by calling 1-800-FDA-1088.

Warnings

Solifenacin should not be used in the case of untreated, uncontrolled narrow angle glaucoma or blockage in the digestion tract (stomach or intestines) or if you cannot urinate.

Before you Take this Drug

It is not recommended to use solifenacin when you are allergic to it or are suffering from:

  • Untreated or uncontrolled narrow-angle glaucoma
  • A stomach disorder causing delayed emptying;
  • If you're unable to urinate.

Speak to your doctor if you have ever suffered from:

  • Glaucoma;
  • Liver disease;
  • Kidney disease;
  • Difficulty in emptying your bladder (or you're experiencing a weak flow in your urine);
  • Slow digestion;
  • A blockage in your stomach, intestines,
  • Long QT syndrome.

It isn't known if this medicine could cause harm to a baby who is not yet born. Inform your doctor if you are expecting or planning to be pregnant.

You shouldn't breastfeed when taking solifenacin.

How to Take Solifenacin?

Follow the directions on the prescription label and read the medication guide or instructions sheets. Make sure you use the medicine precisely as directed.

Solifenacin is typically taken once every day, in combination with or without food. Follow the prescriptions of your physician.Do not chew, crush, tear, or break the tablet. Suck it up whole.

Make sure to shake off your oral suspension (liquid) prior to taking the dosage. Make use of the dosing syringe supplied or a dosage-measuring device (not the kitchen spoon).Drink tablets. Mix the tablets with water.After drinking solifenacin, take a glass of milk or water. Beware of taking the liquid along with other drinks or food, or you might experience an unpleasant taste.

The solifenacin should be stored in the original container at room temperature, away from heat and moisture. Close the bottle when not being used. Discard any unopened liquid for 28 days from the time you first opened the bottle.

Details on Dosage

Usual Adult Dose for Urinary Incontinence:

Initial dose: 5 mg taken orally every day.
Maintenance dosage: 5–10 mg once a day, orally
Use: To treat a bladder that is overactive and has signs of urgency, incontinence, or urgency. Also, frequent urinary discharge

Usual Adult Dose for Urinary Frequency:

Initial dosage: 5 mg orally every day.
Maintenance dosage: 5 to 10 mg taken orally daily.
Use: To treat an overactive bladder accompanied by signs of urinary urge or urgency as well as urinary frequency.

What Happens If I Miss a Dose?

Tablets: skip the dose you missed and take your dose next at normal time. Don't take two doses on the same day.

Oral suspension: Consume the medication as soon as you are able, but do not take your missed dose if you have been more than twelve hours behind on the dose. Don't take two doses at the same time.

What Happens If I Overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

What Should be Avoided?

Avoid driving and other hazardous activities until you understand how the effects of solifenacin affect your body. Your reaction could be affected.

Beware of becoming dehydrated or overheated during workouts and in hot temperatures. Solifenacin reduces sweating and increases your risk of becoming vulnerable to heat stroke.

Interaction with Other Drugs

There are times when it's not safe to take certain medications simultaneously. Certain drugs may affect your blood levels and the other drugs you are taking, which could create side effects or render the drugs less effective.

A variety of drugs can affect solifenacin. This includes prescription and over-the-counter medicine, vitamins, and herbal supplements. Not all interactions are included in this list. Inform your doctor of your current medications as well as any other medications you take or stop taking.

DRUG STATUS

Availability

Prescription only

Pregnancy & Lactation

CSA Schedule*

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