What is Fam-trastuzumab deruxtecan?
Fam trastuzumab deruxtecan is a treatment for adults who are positive for HER2 breast cancer that has spread to other regions within their organs (metastatic) or is not treated with surgical intervention. Fam-trastuzumab deruxtecan may also be utilized in adult patients who have had anti-HER2 cancer treatment prior to the metastatic cancers or suffer from breast cancer that came in the last 6 months after finishing treatment for early-stage breast cancer. Fam-trastuzumab Deruxtecan is also available for adults to treat a specific type of HER2-positive esophageal cancer. Fam-trastuzumab Deruxtecan is typically used after other treatments for cancer have failed or ended their effectiveness. Fam-trastuzumab deruxtecan can also be used to treat conditions that are not mentioned in this guide.
Side effects of fam-trastuzumab deruxtecan
See a doctor immediately. If you are experiencing warning signs of an allergic response, such as symptoms of hives, difficulty breathing, and swelling of your lips, face, or tongue. Fam-trastuzumab, deruxtecan, may cause serious side effects. Contact your physician immediately if you experience:
- Chest tightness coughing, coughing new or more severe chest tightness, wheezing or coughing; shortness of breath.
- Pounding or fluttering heartbeats in your chest.
- Fever, tiredness, and dizziness.
- The swelling of your lower legs and weight gain suddenly.
- A feeling of lightheadedness, as if you're about to pass out.
- Low blood cell counts, fever, mouth sores, chills, skin sores, simple bruising or bleeding that is unusual, pale skin, cold feet and hands.
- Lower potassium level: leg cramps, constipation irregular heartbeats The chest flutters with more frequent urination or thirst. Numbness or tingling in the muscles, becoming weak, or a limp sensation.
Your treatment for cancer could be delayed or completely stopped when you experience certain negative side effects.
Common adverse effects of fam-trastuzumab deruxtecan could be:
- Vomiting, vomiting, and a loss of appetite.
- Diarrhea, constipation.
- Fatigue, fever.
- Low blood cell count.
- Low potassium.
- Abnormal tests of liver function.
- Hair loss.
This isn't a complete list of all the side effects. Others could happen. Consult your physician for advice regarding medical effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.
Fam-trastuzumab deruxtecan could cause life-threatening or serious adverse reactions to the lungs or your heart. Call your doctor immediately if you notice symptoms of fatigue, coughing, chest tightness, dizziness, breathing problems, irregular heartbeats, or sudden or increased shortness of breath. Fam-trastuzumab deruxtecan could decrease (suppress) the immune system. As a result, you might develop an infection or have more rapid bleeding. Inform your doctor in the event of unusual bleeding or bruising or if you have signs of an infection (fever, chills, weakening, chills, cold or cold symptoms, or a frequent or repeated illness). Both women and men who are taking fam-trastuzumab deruxtecan must utilize effective birth control methods to avoid pregnancies. Birth control should be maintained until 7 months following your last dosage of famtrastuzumab deruxtecan in women and for 4 months in men.
Before you take this drug
Speak to your doctor if you have ever suffered from:
- Heart issues.
- Breathing issues breathing problems.
- An infection.
It is possible that you will need to take an unfavorable pregnancy test prior to beginning this treatment. Fam-trastuzumab deruxtecan could cause harm to a baby who is not yet born if either the father or the mother uses this medicine.
- If you're pregnant, do not use fam-trastuzumab deruxtecan when you are expecting. Make sure you use effective birth control methods to stop pregnancy while taking this medication and for at least seven months following the last dose.
- If you're male, use effective birth control if you have a partner who can get pregnant. Continue using the birth control pill for at least 4 months after the last dose.
- Contact your physician immediately when you notice a pregnancy when one of the mothers or fathers is taking fam-trastuzumab deruxtecan.
This medication can affect fertility (the ability to bear kids) in men.
Don't breastfeed while taking this medicine or for at least seven months after the last dose.
How to take Fam-trastuzumab deruxtecan?
Your doctor will run blood tests to confirm that there are no conditions that could make it unsafe to use deruxtecan fam-trastuzumab. Fam-trastuzumab deruxtecan can be given as an infusion to the vein. Your healthcare professional will offer the injection.
Fam-trastuzumab Deruxtecan is usually administered every 3 weeks during the course of a 21-day treatment. The doctor you consult will decide the duration of treatment with deruxtecan fam-trastuzumab. It is possible to receive medication to help prevent vomiting or nausea during treatment with fam-trastuzumab deruxtecan. You'll require regular medical examinations.
Deatils on dosage
Usual Adult Dose for Breast Cancer:
5.4 mg/kg IV once every three months (a 21-day course) until progression of the disease or toxicity is unacceptable.
Comments: The first infusion should be administered over 90 minutes. Then administer the subsequent infusions for 30 minutes if the previous infusions were tolerated.
Reduce or stop the rate of infusion if the patient is experiencing symptoms associated with infusions.
You should stop treatment immediately for any serious infusion reactions.
Use: To treat patients who are adults with non-resectable or metastatic breast cancer that is HER2-positive and who have received two or more anti-HER2-based therapies in the metastatic setting.
What happens if I miss a dose?
Consult your physician for treatment in the event that you don't make an appointment to receive your fam-trastuzumab deruxtecan injection.
What happens if I overdose?
Because fam-trastuzumab deruxtecan can be administered by a medical expert in a medical environment, it is highly unlikely for an overdose to occur.
What should be avoided?
Follow your doctor's advice regarding any limitations on foods, drinks, or any activity.
Interaction with other drugs
Other medications may interact with the fam-trastuzumab dextecan medication, which includes medications that are prescribed and available over the counter, vitamins, and herbal products. Inform your doctor about your current medications and any medications you begin or stop taking.