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Sinus Congestion and Pain Daytime Cool Ice

Generic name: [a-SEET-a-MIN-oh-fen-and-FEN-il-EFF-rin]acetaminophen and phenylephrine

Brand names: Acetaminophen Congestion and Pain, Alka-Seltzer Plus Cold and Sinus, Excedrin Sinus Headache, Mygrex,

Drug class: upper respiratory combinations

What is Sinus Congestion and Pain Daytime Cool Ice?

Acetaminophen can be used to reduce fever and relieve pain. Phenylephrine shrinks the blood vessels of the nasal passages. Dilated blood vessels can cause congestion in the nasal passages.

The combination medicine Sinus congestion and pain Daytime Cool Ice treats headaches, fever, body pains, stuffy noses, and sinus congestion caused by allergies, the common cold, or the flu. This medication guide does not list all possible uses for Daytime Cool Ice Sinus Congestion and Pain.

Side effects of Sinus Congestion and Pain Daytime Cool Ice

If you experience any of the following signs and symptoms of an allergic reaction: hives, difficulty breathing or swelling of lips, face, tongue or throat. Seek medical assistance immediately.

Acetaminophen can cause serious, even life-threatening reactions - even if you've taken it before and never experienced adverse symptoms. Call your doctor immediately if you experience skin redness, blistering, or peeling.

The medicine can cause serious side effects. If you experience:

  • Heart rate can be fast, slow, or uneven.
  • Confusion, hallucinations;
  • Tremor, seizure (convulsions);
  • Little or no urinating is acceptable.
  • If you experience nausea, upper abdominal pain, itching, or loss of appetite; or if you have dark urine or clay-coloured stool; or if you suffer from jaundice, yellowing of the skin and eyes, or a loss of appetite
  • The symptoms of dangerous hypertension include severe headaches, blurred or buzzing vision, anxiety, confusion, and chest pain.

Side effects of Sinus Congestion Daytime Cool Ice include:

  • Dizziness, weakness;
  • Mild headache
  • Mild nausea, diarrhoea, upset stomach;
  • Runny nose
  • Feeling nervous, restless, or anxious
  • Sleep problems (insomnia).

There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.

Similar/related drugs

Epinephrine topical, pseudoephedrine, phenylephrine nasal, sodium chloride nasal, mometasone nasal, Afrin, and Nasonex Allergy 24HR


You should not take this medication if you've taken an MAO inhibitor in the last 14 days. Harmful drug interactions may occur. MAO inhibitors are isocarboxazid linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Don't take more than recommended. An acetaminophen overdose can cause liver damage or death. Acetaminophen can cause severe skin reactions in rare cases. If you notice skin redness, a rash, blistering, or peeling of the skin, stop taking this medication and contact your doctor immediately.

Before you take this drug

If you have an allergy to acetaminophen or phenylephrine (Tylenol), then you should not use Sinus Congestion and Pain Daytime Cold Ice. If you have taken a MAO inhibitor within the last 14 days, do not take this medication. It is possible that a dangerous drug interaction will occur. MAO inhibitors are isocarboxazid (linezolid), phenelzine (phenelzine), rasagiline (selegiline), and tranylcypromine.

If you have any other medical conditions or concerns, ask your doctor or pharmacist whether it's safe to take the medicine.

  • Liver diseases, alcoholism, or a history of drinking more than three alcoholic drinks per day are all signs.
  • Coronary heart disease and high blood pressure.
  • Overactive thyroid
  • Pheochromocytoma
  • If you are taking an antidepressant,

There is no way to know if sinus congestion and pain from daytime cold ice will harm a baby. If you are pregnant, do not take cough and cold medicines without consulting your doctor.

Acetaminophen, phenylephrine, and other drugs can pass through breast milk. This may cause harm to a nursing infant. Decongestants can also reduce breast milk production. If you are pregnant, do not take cough and cold medicines without consulting your doctor. Never give cough or cold medications to very young children without consulting a doctor.

How to take Sinus Congestion and Pain Daytime Cool Ice?

Do not exceed the recommended dosage. Use only as directed. Cold medicines are usually only taken for a few days until symptoms disappear. Don't take more than the recommended dose. Acetaminophen overdoses can cause liver damage or death.

One packet of powder should be dissolved in 4 ounces or more of water. Mix this mixture well and consume it immediately. Drop the effervescent tablet into a glass full of water (at least 4 ounces or half a cup). This mixture should be stirred and consumed immediately.

If you continue to have a high fever or pain for more than 7 days (or five days in the case of a child), or if any of your symptoms worsen, such as a skin rash or persistent headache, call your doctor. Tell your doctor or surgeon, if you've taken this medication within the last few days, if you are going to need medical testing or surgery. Store away from heat and moisture at room temperature.

What happens if I miss the dose?

You may not have a schedule for taking Sinus Congestion and Pain Daytime Cold Ice. It is only taken as needed. Take the missed dose immediately if you take the medication regularly. If your next scheduled dosage is approaching, skip the missed dose. You should not take more medicine to compensate for a missed dose.

What happens if I overdose?

Call the Poison Help Line at 1-800-222-1222 or seek emergency medical care. Acetaminophen overdoses can be deadly. Loss of appetite, nausea and vomiting, abdominal pain, sweating, or confusion are the first signs of an overdose of acetaminophen. Other symptoms include dark urine and a yellowing of the skin or whites of the eyes.

What should be avoided?

This medication can impair your reactions or thinking. You should be careful when driving or doing anything else that requires alertness.

Before using any other medication for colds, allergies, pain, or sleep, consult your doctor or pharmacist. Many combination medications contain acetaminophen, also known as APAP. Taking some products together may cause an overdose of acetaminophen, which could be fatal. Avoid alcohol. Acetaminophen can increase the risk of liver damage.

Interaction with other drug

Other drugs, such as prescription and over-the-counter medicines, vitamins, and herbal supplements, may also interact with acetaminophen or phenylephrine. Inform your healthcare providers of all the medicines you are currently taking and those you plan to start using.