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Mafenide topical

Name of the Generic: Mafenide topical [MAF-en-ide] MAF-en-ide.
Name of the Brand: Sulfamylon.
Dosage Formats: Topical cream (85 mg/g) and topical powder to reconstitute (5 percent).
The Class of Drug: Topical antibiotics.

What is Mafenide?

Mafenide acts as an antibiotic that fights the presence of bacteria in the body. Topical mafenide (for the face) is used to stop infections in burn wounds of severe severity. Mafenide can also be used for reasons not mentioned in this guideline.

Side effects of Mafenide

Contact a medical professional immediately. If you notice any of the following symptoms, they are warning signs of an allergic reaction. difficulty breathing, and swelling of your lips, face, or tongue. Contact your family caregivers right away. If you suffer from:

  • Skin that is pale or yellowed; dark-colored urine; the feeling of fever and weakness.
  • Rapid breathing.
  • Skin or bruising, an extreme sensation of numbness, tingling, and muscle weakness.
  • Extremely severe skin irritations when the medicine is sprayed.

Common adverse consequences of topical mafenide could include:

  • Itching, redness, or blisters; irritation of the skin treated.
  • Burning or pain on the treated skin.
  • The white, skin-like, or "pruned" appearance of the skin (caused by putting dressings for wounds on for a long period of time).

This is not a comprehensive list of possible side effects, and other side effects could be present. Contact your doctor for advice regarding medical adverse effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.


Follow the directions on the medicine label and the package. Inform your health care providers about your medical ailments, allergies, and any medications you take.

Before you take this drug

It is not recommended to use mafenide topical if you have an allergy to mafenide. To ensure that mafenide topical is suitable for you, inform your doctor if:

  • Kidney disease.
  • Glucose-6-phosphate dehydrogenase (G6PD) insufficiency is a hereditary enzyme deficiency.
  • Asthma or sulfite allergy as well as.
  • If you're sensitive to sulfa-containing drugs.

FDA pregnancy category C. It is not clear whether mafenide's topical effects will affect a newborn baby. Consult your physician if you are expecting or are planning to become pregnant while taking this medication. It is unclear if mafenide's topical metabolites are absorbed by breast milk or may harm a nursing infant. When using this drug, do not breastfeed.

How to take Mafenide?

The doctor will help you determine the appropriate dosage and form of mafenide that you need to take. The medication will be administered in a burn unit. Mafenide cream is typically applied to burns at least once a day. The wound must be covered by this medication throughout treatment.

Mafenide powder can be combined with a saline solution and then put on top of a gauze dressing by using a syringe or an irrigation tube. Mafenide is generally applied several times a day to keep the dressing moist.

What happens if I miss a dose?

Because you'll be receiving mafenide topical treatment in a clinical setting, you're not likely to skip the dose.

What happens if you miss a dose?

Because mafenide topical is administered by a medical expert in a medical environment, the risk of overdose is less likely to occur.

What should be avoided?

Follow the doctor's advice regarding food, drinks, or any activity.

Interaction with other drugs

It's not likely that other medications you take in the form of injections or orals can affect the mafenide you apply topically. But there are many drugs that interact with each other. Be sure to inform your health care professionals about the medicines you take, which include prescription and non-prescription medications, vitamins, and herbal remedies.