What is Ryzodeg FlexTouch Pen?
Ryzodeg is a combination of insulin, aspart, and degludec. Insulin is a hormonal substance that lowers the levels of sugar (glucose) in your blood. Insulin aspart has a rapid-acting Insulin degludec has a longer-lasting effect. This combination of insulin begins to work 10 to 20 minutes following the injection. It reaches its peak in an hour and continues to function for up to 24 hours. Adults with diabetes mellitus can use Ryzodeg to control their blood sugar levels. Ryzodeg can be used to treat type 1 or 2 diabetes.
Warnings
Ryzodeg should not be used if you have hypoglycemia. Do not share an injection pen of Ryzodeg with anyone else, even if it has had the needle changed.
Before you take this drug
Ryzodeg should not be used if you have an allergy to insulin degludec or insulin aspart or are experiencing hypoglycemia.
Ryzodeg cannot be used by anyone under the age of 18.
Tell your doctor about any of the following to ensure that Ryzodeg will be safe for you:
- Liver or kidney disease
- Hypokalemia is a condition in which there are low potassium levels in the blood.
- Diabetic ketoacidosis: Call your doctor to get treated.
Inform your doctor if other diabetes medications are being taken, such as pioglitazone and rosiglitazone. Ryzodeg can increase the risk of heart problems if you take certain oral diabetes medications. If you're pregnant, follow your doctor’s instructions for using Ryzodeg. During pregnancy, blood sugar control is essential. Your dose may change during each trimester. If you are breastfeeding, ask your doctor if Ryzodeg is safe to use. You may need a different dose while nursing.
Similar/related drugs
Metformin, Trulicity, Lantus, Victoza, Tresiba, Levemir, and Basaglar
How to take Ryzodeg FlexTouch Pen?
Follow the instructions on your prescription label. Please follow all the instructions on the prescription label. Use this medication only as directed.Do not exceed the prescribed dosage or continue taking it longer than required. Ryzodeg can be injected into the skin. You will be taught how to inject at home. You should not inject yourself with Ryzodeg until you understand how to properly use the injection. Ryzodeg should not be mixed with insulin pumps or other insulins. Ryzodeg can be taken once or twice a day with any meal. Depending on your needs, you may have to use another fast-acting type of insulin for other meals. You should follow your doctor's instructions for dosage very closely.
Your healthcare provider will show you the best spots on your body where you can inject Ryzodeg. Each time you inject, use a new place. Don't inject in the same spot twice. Even if you have changed the needle, never share an injection pen. These devices can spread infections and diseases from person to person. Use a single disposable needle. Use syringes and needles only once. Ask your pharmacist how you can dispose of sharps safely in a puncture-proof container that should remain out of reach from pets and children. Everyone with diabetes can experience low blood sugar. The symptoms of low blood sugar include headaches and irritability. You may also experience nausea, sweating, or dizziness. Always keep sugary foods such as hard candy, raisins, crackers, or non-diet soft drinks on hand to treat low blood sugar.
If you are suffering from severe hypoglycemia and can't eat or drink anything, your doctor may prescribe an emergency glucagon injection kit. Make sure that your family members and friends are familiar with how to administer this emergency injection. Watch for other signs of hyperglycemia (high blood sugar), such as an increased thirst, increased urination, or blurred vision. Also, fatigue, headaches, and blurred vision are all possible symptoms. Stress, illness, surgery, and alcohol consumption can affect blood sugar levels. Consult your doctor before adjusting your insulin dosage or schedule. Ryzodeg may be part of a comprehensive treatment plan that includes diet, exercise, and weight management, as well as regular blood glucose testing and medical attention. You should follow your doctor's advice. This medicine should be stored in the original container, away from heat and sunlight. Ryzodeg should not be frozen or stored near the cooling elements in a fridge. Do not use Ryzodeg, which has been frozen.
Ryzodegs that are not in use (not opened) can be stored.
- Refrigerate and use prior to the expiration date.
Ryzodeg:
- Use the pen within 28 days. Store at room temperature. Store the pen without the needle.
If the color of your medicine has changed or if you notice that it is cloudy, do not use it. For new medication, call your pharmacist. Please read all information provided, such as medication guides and instructions. If any queries arise, contact either your physician or pharmacist immediately.
Details on dosage
Adult dosage of Ryzodeg in Type 1 diabetes:
Adjustments should be made based on clinical response.
Insulin-naive patients:
Initial dose: Subcutaneously, inject one-third to half of the daily insulin requirements.
Insulin-naive patients require a total of 0.2–0.4 units per kilogram of body weight.
Switching to once or twice-daily premix insulin
Start at the same dose and schedule of injection as your current insulin premix.
For meals that are not covered by the insulin mix, use short-acting or rapid-acting insulin.
Switching to once or twice daily basal insulin:
Start at the same dose as basal insulin, once daily with the main meal.
For meals that are not covered by the insulin mix, use short-acting or rapid-acting insulin.
Comments:
Adjust dosage according to metabolic requirements, blood glucose measurement, and glycemic goal.
Dose adjustments should be based on the morning fasting blood sugar measurement (before breakfast).
When changing treatment regimens, it may be necessary to adjust the dosage and frequency of rapid-acting or short-acting insulin.
To minimize hypoglycemia closely monitor your blood glucose levels, especially when changing your regimen.
Use: To improve the glycemic level in diabetic patients.
Adult dosage of Ryzodeg in Diabetes Type 2:
Initial dose: subcutaneously, 10 units once per day.
Switching to once or twice-daily premix insulin
Start subcutaneously with the same dose unit and injection schedule as the current self-mixed or premixed insulin.
For meals that are not covered by the insulin mix, you can use short-acting or rapid-acting insulin.
Switching to once or twice daily basal insulin:
Start at the same dose as basal insulin, once daily with the main meal.
Monitor blood glucose levels after starting treatment if you are switching from basal insulin once daily to this insulin mixture. This is due to the rapid-acting insulin component.
For meals that are not covered by the insulin mix, you can use short-acting or rapid-acting insulin.
Comments:
Adjust the dosage based on metabolic needs, blood sugar measurements, and glycemic targets. Dose increases should not occur more than 3–4 days apart.
When changing treatment regimens, it may be necessary to adjust the dosage and frequency of insulin, whether it is rapid or short-acting, or any other anti-diabetic medication.
To minimize hypoglycemia closely monitor your blood glucose levels, especially when changing regimens.
Use: To improve the glycemic level in diabetic patients.
What happens if I miss the dose?
Continue your regular dosing schedule. Continue your normal dosing schedule. Don't use extra insulin to compensate for the missed dose. Ryzodeg should always be available. Refill your prescription before you run completely out.
What happens if I overdose?
Call the Poison Help Line at 1-800-222-1222 or seek emergency medical care. An insulin overdose can lead to life-threatening hypoglycemia. The symptoms include confusion, drowsiness or blurred vision, numbness in the mouth or tongue, difficulty speaking, muscle weakness, or jerky movements.
What should be avoided?
Check the label of your medication before you inject it to avoid any mistakes. Avoid alcohol. Alcohol can cause low sugar levels and interfere with diabetes treatment.
Side effects of Ryzodeg FlexTouch Pen
If you experience any of the following symptoms of an allergic reaction: hives or rashes, difficulty breathing, fatigue, feeling as if you may pass out, nausea, diarrhea, swelling of your lips, face, tongue, or throat, call 911.
If you experience:
- Fluid retention can manifest as swelling of the hands or feet or weight gain.
- Low potassium can cause leg cramps or constipation. It may also lead to irregular heartbeats or chest fluttering. Other symptoms include increased thirst, increased urination or numbness, tingling or numbness, or muscle weakness.
Ryzodeg may cause side effects such as:
- Low blood sugar
- Itching, mild skin rash
- The skin may become thicker or hollowed out where the medication was injected.
There may be other side effects. For medical advice on side effects, call your doctor. Contacting the FDA in regards to potential side effects can be done via their toll free number at 1-800-FDA-1088.
Interaction with other drug
Other medicines can also affect your blood glucose, and some can increase or decrease insulin's effects. You may also experience fewer hypoglycemia symptoms if you take certain drugs, making it more difficult to detect low blood sugar.Inform healthcare providers of any medications you currently take or plan to take.Include prescription, over-the-counter, herbal, and vitamin products.
