What is Rhophylac?
Rhophylac is a source of RHO (D). Rho (D), immune globulin, is a sterile solution of human blood. Most people (Rh positives) have Rh in their blood, but others (Rh negatives) do not. Rh-negative people can be exposed by a transfusion of Rh-positive blood or if the baby is born with the opposite blood type. The Rh-negative blood will produce antibodies to try and destroy the Rh-positive cells. This can lead to medical complications such as shock, kidney failure, or anemia (low blood red cells).Rhophylac prevents an immune reaction to Rh-positive blood when people with Rh-negative blood types are exposed to it. Rhophylac can also be used to treat immune thrombocytopenic purpura (ITP).Rhophylac can be used in other ways not mentioned in this guide.
Warnings
Rhophylac should not be given to people with hemolytic anemia or immune globulin A deficiency (iga).RHO(D), an immune globulin, can cause an abnormal breakdown of red blood cells. This can cause life-threatening blood or organ failure.Symptoms that you should immediately notify their physician of. Fever, chills, or back pain Pale skin or red urine. Feeling short of breath.You must inform your doctor if you are Rh-negative and become pregnant and if you've ever been exposed to Rh-positive blood. It includes exposure due to a mismatched transfusion or during your first pregnancy. It is important to know your history of treatment and exposure for each of your pregnancies.
Before you take this drug
Rhophylac should not be given to you if:
- Immune globulin A deficiency (iga), with antibodies to iga
- Hemolytic anemia occurs when there aren't enough red blood cells.
Tell your doctor about any of the following to ensure that Rhophylac will be safe for you:
- Anemia history;
- Heart disease or an antecedent of coronary artery disease (hardened arteries);
- A bleeding disorder (such as hemophilia);
- Triglycerides, or fat found in blood plasma, may increase, posing an increased health risk to an individual's overall wellness.
- Kidney disease
Rhophylac can be used before and after pregnancy. This medication is not harmful to the baby when breastfeeding or during pregnancy.Tell your doctor that you plan to get pregnant if you receive Rhophylac for a mismatched transfusion.You must inform your doctor if you are Rh-negative or if you've ever received Rh-positive blood during your lifetime. This can include exposure through a mismatched transfusion or even exposure during your first pregnancy. It is important that you tell your doctor about any exposure to Rh-positive blood in the past. This includes mismatched transfusions or even a first pregnancy.Rhophylac (a part of blood) is made with human plasma, which can contain viruses and infectious agents. The plasma donated is treated and tested to reduce the possibility of it being infected, but it is still possible that it could spread disease. Speak to your doctor about Rhophylac's risks and benefits.
How to take Rhophylac?
Rhophylac can be injected directly into a muscle or vein. This injection will be given in a hospital or clinic setting.After receiving immune globulin, your vital signs, such as breathing, blood pressure, and oxygen levels, will be closely monitored. You may need to have your urine tested every 2 to 3 hours for at least eight hours.Rhophylac can be given to pregnant women at regular intervals in the second half of pregnancy and after delivery.Rhophylac can be used to treat a mismatched transfusion when the symptoms of an allergic reaction (when the body begins producing Rh antibodies) appear.You may need to have frequent blood tests to ensure that this medication is helping you. Your doctor will determine the length of treatment based on your blood tests, even if you don't notice any changes in your symptoms.Rhophylac may cause false readings in certain lab tests that measure glucose (sugar). Tell your doctor that you use this medication.
What happens if I miss the dose?
If you missed your Rhophylac appointment, call your doctor to get instructions.
What happens if I overdose?
Call 1-800-222-1222 for poison help or seek immediate medical attention.
What should be avoided?
After treatment with Rhophylac, do not receive any "live" vaccinations for at least three months. During this period, the vaccine may not be as effective, and you may not be fully protected from disease. Live vaccines are available for measles (MMR), rubella, mumps (MMR), yellow fever, typhoid (typhoid), varicella, chickenpox, zoster, and influenza (nasal flu).
Side-effects of Rhophylac
If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: rash, hives, feeling lightheaded, chest pain, difficulty breathing, swelling of your lips, face, tongue, or throat.
If you experience:
- Back pain, unusual weakness, and fever are all symptoms of red or pink urine.
- Dark urine, pale or yellow skin;
- Rapid breathing, rapid heartbeat, confusion, feeling of shortness of breath
- Signs of kidney failure include swelling, little or no urine, and rapid weight gain.
- Signs of a blood clot include sudden numbness, weakness or slurred words, difficulty with vision, balance, or chest pain. Other symptoms are coughing and swelling in the legs with redness.
Rhophylac can cause a variety of side effects.
- Nausea, diarrhea, vomiting, and stomach pain;
- Headache, dizziness;
- Drowsiness, weakness, and a general bad feeling
- Joint or muscle pain
- Flushing (warmth, redness, or tingling feeling)
- The itching and skin rash are mild.
- Increased sweating
- Pain or tenderness at the injection site.
There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.
Interaction with other drug
Rhophylac may interact with other drugs, such as prescription and over-the-counter medicines, herbal products, and vitamins. Inform your healthcare providers of all medications you are taking, including any new ones.
