What is RHo(D) immune globulin?
RHO (D), immune globulin, is a solution sterilized from human blood. Most people (Rh-positive) have Rh in their blood, but others (Rh-negative) don't. Rh-negative people can be exposed by a mismatched transfusion or through pregnancy when the baby is of the opposite blood type. This exposure will cause the Rh-negative blood to produce antibodies that try to destroy Rh-positive blood cells. It can lead to medical complications such as low red blood cells, kidney failure, or shock.rho (D), immune globulin, is used to treat immune thrombocytopenic purpura in patients with Rh-negative blood types. RHO (D), an immune globulin, may also be used to treat immune thrombocytopenic purpura (ITP).This medication guide does not list all possible uses of RHO (D).
Side effects of RHo (D) immune globulin
If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: skin rash, hives, feeling lightheaded, chest pain, difficulty breathing, swelling of your lips, face, tongue, or throat.
RHO (D) immune globulin may cause serious side effects. If you experience:
- Backache; chills and shaking; unusual weakness;
- Dark urine, pale or yellow skin;
- Rapid breathing, rapid heartbeat, confusion, feeling of shortness of breath
- Signs of kidney failure include swelling, little or no urinating, and rapid weight gain.
- Signs of a blood clot include sudden numbness, weakness or slurred words, difficulty with vision, balance, or chest pain. Other symptoms are coughing and swelling in the legs with redness.
Some of the common side effects associated with RHO (D), immune globulin, include:
- Nausea, diarrhea, vomiting, and stomach pain;
- Headache, dizziness;
- Weakness, a general feeling of ill-feeling, drowsiness;
- Joint or muscular pain
- Flushing (warmth, redness, or tingling feeling)
- Itching on the skin or mild
- Increased sweating
- Pain or tenderness at the injection site.
There may be other side effects. For medical advice on side effects, call your doctor. Contact the FDA by dialing 1-800-FDA-1088 in order to report adverse side effects.
Similar/related drugs
Nplate, Promacta, Tavalisse, Doptelet, Prednisone, Dexamethasone, and Triamcinolone
Warnings
If you have hemolytic anemia, you should not receive RHO (D) immunoglobulin.RHO(D), an immune globulin, can cause a breakdown of red cells. This can cause life-threatening blood or organ failure.If you experience any of these symptoms, call your doctor immediately. Fever, chills, or back pain Pale skin or red urine. Feeling short of breath.
Before you take this drug
This medicine should not be given to you if:
- Immune globulin A deficiency (iga), with antibodies to iga
- Hemolytic anemia is a condition in which there are not enough red blood cells.
Tell your doctor about any of the following to ensure that RHO (D), immune globulin, is safe for you:
- Anemia history;
- Heart diseases, or a family history of coronary arterial disease;
- A bleeding disorder, such as hemophilia;
- High triglycerides
- Kidney disease
- Diabetes.
RHO (D), an immune globulin, is commonly used during and following pregnancy. It is known that this medicine will not harm a baby while pregnant or breastfeeding.Tell your doctor that you plan to get pregnant if this medication is prescribed to treat an incorrect blood transfusion.You must inform your doctor if you are Rh-negative or if you've ever received Rh-positive blood during your lifetime. This can include exposure through a mismatched transfusion or even exposure during your first pregnancy. It is important that you tell your doctor about any exposure to Rh-positive blood in the past. This includes mismatched transfusions or even a first pregnancy.RHO (D), immune globulin, is made of human plasma (a part of the blood), which can contain viruses and infectious agents. Plasma donated is treated and tested to reduce the possibility of it being infected, but it is still possible that it can transmit disease. Speak to your doctor about any risks or benefits associated with using this medication.
How to take RHo (D) immune globulin?
Immunoglobulin RHO (D) is injected into a vein or muscle. This injection will be given in a hospital or clinic setting.After receiving immune globulin, your vital signs, such as breathing, blood pressure, and oxygen levels, will be closely monitored. You may need to have your urine tested every 2 to 3 hours for at least eight hours.When used as a treatment for pregnancy, RHO(D) immune-globulin should be given regularly during the second half of pregnancy and after the birth.The medicine is administered when the symptoms of an allergic reaction (when the body begins to produce Rh antibodies) appear.You may need to have frequent blood tests to ensure that this medication is helping you. Your doctor will determine the length of treatment based on your blood tests, even if you don't notice any changes in your symptoms.RHO (D), immune globulin, can produce false results in certain lab tests that measure glucose. Inform any doctor that treats you about the use of this medication.
What happens if I miss the dose?
If you missed your appointment for the RHO (D) immunoglobulin injection, call your doctor to get instructions.
What happens if I overdose?
Call 1-800-222-1222 for poison help or seek immediate medical attention.
What should be avoided?
After receiving RHO (D), immune globulin, do not receive any "live" vaccines for at least three months. During this period, the vaccine may not be as effective, and you may not be fully protected from disease. Live vaccines are available for measles (MMR), rubella, mumps (R), rotavirus (typhoid), yellow fever (YF), varicella, chickenpox (shingles), typhoid (Typhoid), and influenza (nasal flu).
Interaction with other drug
Other drugs, such as vitamins and herbal remedies, may also interact with RHO-D immunoglobulin. Inform your healthcare providers of all the medicines you are taking and those you plan to take.
