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Rexaphenac

Generic name: diclofenac topical [dye-KLOE-fen-ak-TOP-ik-al]
Brand Names: Aspercreme Arthritis Pain. Dicloprep 100. Motrin Arthritis Pain, Pennsaid Rexaphenac.
Drug class: topical anti-inflammatory non-steroidal creams

What is Rexaphenac?

Diclofenac (NSAID) is a nonsteroidal analgesic drug.Rexaphenac is used for the treatment of joint inflammation that results from osteoarthritis. Rexaphenac can be used on the elbows, hands, feet, ankles, or knees. This medication may not work to treat arthritis pain in other parts of the body.Pennsaid should only be used on the knees.Solaraze treats warty skin growths (actinic keratoses), which are found in areas exposed to the sun.Rexaphenac can be used in other ways not mentioned in this guide.

Side effects of Rexaphenac

If you experience symptoms of an allergic reaction, such as hives, sneezing (especially with a runny nose), wheezing (or difficulty breathing), swelling (of the face or throat), or a severe reaction to your skin (fever, sore eyes, burning, or painful skin, or rashes that are red, purple, or blistered and peeling), seek emergency medical attention.If you experience a severe drug reaction, such as a skin rash or fever, seek medical attention. Other symptoms may include muscle pain, severe weakness, unusual bruises, or yellowing in the skin or eyes.If you experience any of these symptoms of a stroke or heart attack: sudden weakness or numbness on one side, slurred or shaky speech, shortness of breath, or chest pain that spreads to the jaw or shoulder,

Call your doctor immediately if you:

  • A skin rash is a rash on the skin, regardless of how mild it may be.
  • Rapid weight gain and swelling
  • Severe headache; blurred vision; or a pounding sensation in the neck or ears
  • Little or no urination
  • Liver problems: nausea; diarrhea; stomach pain on the upper right side; fatigue; itching; dark urine; and clay-colored stools. Jaundice.
  • Low red blood cells (anemia)--pale or pale-colored skin, unusual fatigue, feeling lightheaded or short-of-breath, cold hands or feet;
  • Signs of stomach bleeding include bloody or tarry stool, vomiting blood, or vomit that looks like coffee grounds.

Rexaphenac side effects may include:

  • Nausea and stomach pain.
  • Diarrhea, constipation;
  • Headache, dizziness, drowsiness;
  • Stuffy nose;
  • Itching and increased sweating
  • Increased blood pressure or
  • Skin redness, itching, or scaling where the medication was applied

There may be other side effects. For medical advice on side effects, call your doctor.Contact the FDA by dialing 1-800-FDA-1088 in order to report adverse side effects.

Similar/related drugs

Aspirin, acetaminophen, prednisone, ibuprofen, tramadol, duloxetine, and naproxen

Warnings

Rexaphenac increases your risk of a fatal stroke or heart attack. Rexaphenac should not be used before or after heart bypass surgeries. This medication can also cause fatal stomach or intestinal bleeding.

Before you take this drug

Rexaphenac may increase your risk of a fatal heart attack or stroke even if there are no risk factors. This medicine should not be used before or after heart bypass (coronary arterial bypass graft, or CABG).Rexaphenac can also cause fatal stomach or intestinal bleeding. You may not be aware of these conditions if you use this medication, particularly if you are older.This medicine should not be used if you're allergic to diclofenac, also known as Voltaren (Cataflam, Flector, and other brands), or if your asthma attacks or severe allergic reactions have occurred after you took an NSAID or aspirin.Rexaphenac should not be used by anyone under the age of 18.

Inform your doctor immediately of any of the following issues:

  • Heart condition high blood tension, high cholesterol, diabetes, or if you are a smoker.
  • A heart attack, stroke, or blood clot
  • Stomach ulcers are bleeding stomach or intestinal ulcers.
  • Asthma;
  • Liver or kidney disease
  • Fluid retention.
    Diclofenac may affect ovulation, making it harder to become pregnant.

Do not take Rexaphenac if you are pregnant unless you have been told to by your doctor. Nsaids can cause kidney or heart problems for the unborn child and other complications during pregnancy.Breastfeeding may not be possible while taking this medication. You should consult your doctor if you are concerned about any risks.

How to take Rexaphenac?

Read all the instructions on the label of your medication and follow them. Use the lowest effective dose to treat your condition.Take it only by mouth. Topical medicines are only to be used on the skin. If Rexaphenac enters your mouth or eyes, rinse with water.Please read and follow all instructions that accompany your medication carefully. If you don't understand the instructions, ask your doctor or pharmacist.Rexaphenac should not be applied to open wounds, areas of infection, or rashes.Store at room temperature and away from moisture and heat sources. Store at room temperature, away from moisture and heat.

What happens if I miss the dose?

If you are close to your next dose, skip the missed dose. Never apply two doses at once.

What happens if I overdose?

Call 1-800-222-1222 for poison help or seek immediate medical attention.

What should be avoided?

Avoid alcohol. Alcohol increases your risk of stomach bleeding.Avoid exposure to sunlight or tanning beds. Heat can increase how much diclofenac is absorbed through the skin.Rexaphenac should not be used in the eyes. If you do get Rexaphenac in your eyes, rinse them with water. If you experience eye irritation for more than an hour, call your doctor.Use only Rexaphenac to treat the area. Do not use any other skin products, such as lotions, insect repellants, sunblock, or cosmetics.

Interaction with other drug

Before using diclofenac, ask your doctor if you are taking an antidepressant. Certain antidepressants may cause you to bruise or bleed easily.

Do not forget to inform your physician of all current medications you are taking, such as:

  • Cyclosporine;
  • Lithium;
  • Methotrexate;
  • A blood thinner (Warfarin Coumadin Jantoven);
  • Heart or blood pressure medications, including diuretics or "water pills";
  • Steroids (prednisone and others)

This list isn't complete, and other drugs can also interact with diclofenac. This includes prescription, over-the-counter, and vitamin products, as well as herbal products. This list does not include all possible interactions with drugs.