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Generic name: sevelamer
Drug Class:Phosphate Binder

What is Renvela?

Renvela acts as a phosphate binder. Sevelamer prevents hypocalcemia, or low levels of calcium within the body caused by high phosphorus.Renvela helps control the phosphorus level in patients with chronic renal disease on dialysis.Renvela can be used in other ways not mentioned in this guide.

Side effects of Renvela

If you experience any of the following symptoms of an allergy to Renvela, seek immediate medical attention: difficulty breathing, hives, swelling of the face, lips, or tongue.

If you experience any of the following symptoms, stop using Renvela immediately and contact your doctor.

  • Choking or difficulty swallowing is a common occurrence.
  • Black, bloody, or tarry stools
  • Constipation accompanied by stomach pain or severe constipation
  • Constipation that worsens or doesn't clear up

Common Renvela side effects may include:

  • Vomiting, nausea, and loss of appetite are all symptoms that can be associated with stomach pain.
  • Gas, bloating, upset stomach;
  • Diarrhea, constipation;
  • Tired feeling
  • Itching
  • Joint pain.

There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.


Renvela should not be taken if you are suffering from a bowel obstruction.Tell your doctor before taking Renvela if you suffer from severe constipation or have had recent stomach or intestinal surgery.Do not take any other medicine within an hour of taking Renvela or for 3 hours afterwards. Sevelamer may bind with other medicines and reduce their effectiveness.Tell your doctor if, before taking this medication, you are currently taking ciprofloxacin, a medication for heart rhythm, or a medication to treat seizures.Take calcium and other minerals only on your doctor's recommendation. Only use the calcium or mineral supplements that your doctor has prescribed.

Before you take this drug

Renvela should not be taken if you're allergic to sevelamer or have a bowel obstruction.

Tell your doctor about any of the following to ensure that Renvela will be safe for you:

  • Trouble swallowing
  • Constipation severe;
  • A blockage of your intestines
  • Slow digestion;
  • A stomach or intestinal disorder
  • If you've recently had stomach surgery or a bowel operation,

This medicine is not known to harm a baby in utero. Tell your doctor immediately if you plan to get pregnant. Your dose needs may be different during pregnancy.Renvela can cause your blood levels to drop for certain vitamins and folic acids. You should follow your doctor's advice when it comes to taking vitamin or mineral supplements while pregnant.Sevelamer does not enter the bloodstream and is therefore not harmful to nursing babies.Renvela should not be used by children younger than six years of age.

Similar/related drugs

урсам, Carafate, Sevelamer, Auryxia, Velphoro, and Lanthanum Carbonate

How to take Renvela?

Follow the directions on your prescription label. Please follow all the instructions on the prescription label. Occasionally, your doctor may change the dose you are taking to ensure that you receive the best possible results. Use this medication only as directed. Use the dose recommended and do not use more than that.Renvela can be taken with food.Renvela powder should be dissolved in water before use. Mix the 0.8-gram packet with at least 2 tablespoons of water. The 2.4-gram package should be mixed at least with 2 ounces (4 teaspoons) of water.The powder should be dissolved in the water by stirring. Drink the water immediately after mixing it with powder.Pour the full dose and add some more water to the same glass. Swirl gently, then drink immediately.You may need to have frequent blood tests while using several glasses.If you are having difficulty swallowing the tablets or feel that they are stuck in your esophagus, call your doctor.Renvela is often part of a comprehensive treatment program that includes a special dietary plan. You should strictly follow the diet prescribed by your doctor or nutritionist. To help you control your condition, it is important to become familiar with the foods that you should eat and avoid.Keep away from moisture and heat at room temperature.

Details on dosage

Adult dose for hyperphosphatemia and renal failure:

Initial Dosing: For patients who are not taking a phosphate binder, take 800 mg to 1,600 mg three times daily with meals.
According to serum phosphorus levels:
-Phosphorus less than or equal to 7.5 mg/dL but greater than 5.5 mg/dL: 800 mg 3 times per day with meals
-Phosphorus less than or equal to 9 mg/dL: 1200 to 1660 mg three times daily with meals
-Phosphorus above or equal to 9 mg/dL: 1600 mg 3 times per day with meals
-Titrate by 800 mg every 3 days at intervals of 2 weeks to control serum phosphorus.
Average daily dose: 7.2 grams (2.4 grams with each meal).
Maximum studied dose: 14 g per day (carbonate); 13 g per day (hydrochloride).
If you switch from hydrochloride to carbonate, use the same dose. However, further titrations may be required to reach the desired phosphorus level.
Change from calcium acetate to mg
Comment: Treatment for hyperphosphatemia involves reducing phosphate intake, inhibiting intestinal phosphate absorption with phosphate binder, and removing phosphate through dialysis.
Use: To control serum levels of phosphorus in patients with chronic renal disease on dialysis.

What happens if I miss the dose?

Do not hesitate to take the missed dose. Take the missed dose with food. Skip the missed dosage if your next dose is scheduled soon. Do not increase your dose to make up for the missed one.

What happens if I overdose?

For poison assistance, call 1-800-222-1222 or get immediate medical help.

What should be avoided?

Other medicines should not be taken together. Renvela may make certain medications less effective because it can reduce the body's ability to absorb them.

  • Renvela should be taken 2 hours or 6 hours before ciprofloxacin.
  • Renvela should not be taken for at least 2 hours after taking mycophenolate (CellCept).

Interaction with other drug

Renvela may interact with other drugs, such as prescription and over-the-counter medicines, herbal products, and vitamins. Inform your healthcare providers of all medications you are taking, including any new ones.