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What is Plexion?

Plexion (for your skin) is an antibiotic medicine utilized to manage acne and Rosacea in addition to seborrheic skin dermatitis (a flaking, red, itchy rash). Plexion can also be used to treat conditions that are not mentioned in this guide.

Side effects of Plexion

Contact emergency medical assistance in the event that you exhibit symptoms warning signs (hives and breathing problems and swelling in your throat or face) or a severe skin reaction (fever, sore throat, burnt eyes, irritation, or an ailment that is purple or red with peeling and blisters).

Stop taking Plexion and ask all of your doctors immediately if you experience an outbreak of skin rash that is either worsening or new.

Common adverse effects of Plexion could include:

  • Swelling, redness, heat, itching, burning, stinging, or irritation caused by treatment of the skin

This isn't a complete list of all the side effects. Others could happen. Contact your doctor to seek medical advice on the effects. You may report any adverse reactions to the FDA at 1-800-FDA-1088.

Related drugs

Prednisone, Doxycycline, Metronidazole Topical, Clindamycin Topical, Dexamethasone, Topical Hydrocortisone, and Topical Erythromycin


Take only according to the directions. Inform your doctor if you take other medications or suffer from any other medical condition or allergies.

Before taking this medication

You shouldn't take Plexion in the event that you are allergic to sulfa-based drugs or suffer from kidney disease.

To ensure that Plexion is suitable for you, inform your doctor about all your medical issues. Consult your physician if you are breastfeeding or pregnant. Don't give the medication to children without medical guidance.

How to take Plexion?

Follow the directions on the label of your prescription and read the medication guide or instructions sheets. Follow the medication exactly as prescribed.

The dosage you require could change when you change the brand or strength of this medication. Be sure to use only the medication that was prescribed by your physician.

Cleanse your hands prior to and after applying the medication. Cover the skin unless your physician has instructed you to. Storage at room temperature is free of heat and moisture. Avoid freezing.

Do I be concerned if I miss a dose?

Utilize the medicine as quickly as you can; however, take a break from your missed dosage if it's nearing the time to take the next dose. Do not take two doses at once.

What will happen if I take excessively?

For medical emergencies, seek emergency medical attention or contact the Poison Help Line toll-free at 1-800-222-1222.

What should be avoided?

Do not get this medication in your nose, eyes, or mouth. If it does happen, wash with water. Avoid using it on sunburned, windburned, chapped, dry, irritated, or damaged skin.

Do not use other medicines on the areas that you treat using Plexion unless your physician tells you to.

Interaction with other drugs

Skin care products are unlikely to affect other medicines you take; however, many medications can interact. Inform your doctor about the medicines you are currently taking, including prescription and over-the-counter drugs, vitamins, and herbal remedies.