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Phenoxybenzamine

Generic name: Phenoxybenzamine [fen-OX-ee-BENZ-a-meen]
Brand name: Dibenzyline
Dosage form: oral capsule (10 mg)
Drug class: Miscellaneous cardiovascular agents

What is Phenoxybenzamine?

Phenoxybenzamine can be used to regulate blood pressure and reduce sweating for those suffering from pheochromocytoma (a tumor in the adrenal gland). Phenoxybenzamine can also be employed for other purposes that are not covered in this guideline for medication.

Side effect of Phenoxybenzamine

Contact a medical professional immediately. If you are experiencing symptoms that indicate an allergic reaction, such as hives, difficulty breathing, or swelling of your lips, face, and tongue,

Stop using phenoxybenzamine immediately and consult your doctor immediately in case you experience extreme dizziness or if you think you could be able to pass out.

Common negative side effects of phenoxybenzamine can include:

  • Stuffy nose;
  • Slight dizziness, or dizziness;
  • Blurred vision
  • Difficulty having orgasms;
  • Upset stomach; or
  • Fatigued feeling.

This isn't a complete list of possible side effects, and others could happen. Consult your physician for advice regarding medical effects. You can report any adverse reactions to the FDA at 1-800-FDA-1088.

Warnings

Follow the directions on the label of your medication and on the label of your package. Inform your healthcare professionals about your medical issues, allergies, and any other medications you take.

Related drugs

Propranolol, labetalol, inneral, phentolamine, normodyne, and trandate

Prior to use this drug

It is best not to use phenoxybenzamine in case you have an allergy to it.

Speak to your doctor if you have ever suffered from:

  • Coronary arterial disorder (hardened coronary artery arteries);
  • A lung infection; or
  • Kidney disease.

Inform your doctor if you are expecting. It is not recommended to breastfeed while taking phenoxybenzamine.

How to take Phenoxybenzamine?

Follow the directions on the prescription label and go through all medication guides or instructions sheets. Your doctor may alter the dosage. Follow the medication precisely as directed. Consult your doctor if you are experiencing rapid heartbeats. You might require treatment with another medication. Store phenoxybenzamine at room temperature, far from heat and moisture.

Details on dosage

Usual Adult Dose for Pheochromocytoma:

Initial dosage: 10 mg orally twice a day.
Maintenance dose: 20–40 mg taken orally 2-3 times a day until a dose that is optimal (as determined by blood pressure monitoring) is reached.

What happens if I miss the dose?

Do not take the medicine for as long as you are able, but avoid any missed doses if it's close to the time of the next dose. Don't have two doses at one time.

What happens if I overdose?

For medical emergencies, seek emergency medical attention or contact for help at the Poison Helpline at 1-800-222-1222.

The symptoms of an overdose can include a high heartbeat, vomiting, dizziness, nausea, or fainting.

What should be avoided?

Avoid driving or engaging in hazardous activities until you are aware of the effects of phenoxybenzamine on your body. Your reactions may be affected. Do not get up too quickly from a lying or sitting position. You could be dizzy. Consuming alcohol while taking this medication may cause unwanted side effects.

Interaction with other drugs

Inform your doctor about your other medications, including:

  • Reserpine;
  • Tizanidine;
  • Epinephrine (epi-pen), norepinephrine, or
  • Blood pressure medication.

This list isn't exhaustive. Other medications can affect phenoxybenzamine, which includes prescription and over-the-counter medications, vitamins, and herbal products. Some interactions with drugs are not listed here. are included here.