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Generically: paroxetinepa-ROX-a-teen” ” [pa-ROX-a-tee
The brand names are: Brisdelle, Paxil, Paxil CR, and Pexeva.
Drug class: selective serotonin reuptake inhibitors

What is Pexeva?

Pexeva is an SSRI inhibitor that is selective. (SSRI) medication for depression.Pexeva can be used to treat depression. Pexeva is used to treat depression, which includes major depression disorder. Pexeva can also be used to treat anxiety disorders, obsessive-compulsive disorder (OCD) anxiety disorders, post-traumatic anxiety disorder (PTSD), and premenstrual dysphoria (PMDD).Brisdelle is the Brisdelle version of the drug that helps treat excessive hot flashes that are caused by menopausal symptoms. Brisdelle is not used to treat any other condition. Pexeva is also employed for other purposes that are not covered in this guideline.

Side effects of Pexeva

Seek medical attention immediately. If you notice symptoms warning signs of an allergic response (hives or breathing difficulties and swelling in your throat or face) or an extreme skin reaction (fever and throat soreness, burnt eyes, irritation, and an ailment that is purple or red with peeling and blisters),

If you notice any new or more severe symptoms, tell your physician and include the change in your mood, behavior, or anxieties, panic attacks, and trouble sleeping. also the feeling of being uncontrollably angry, angry, or aggressive. active, restless (mentally and physically), depressed, or contemplating suicide or harming yourself.

Pexeva may cause serious side effects. Contact your doctor immediately. If you suffer from:

  • Racing thoughts, less need to sleep, unusual risks, feelings of extreme sadness or joy, and being more open than usual
  • Blurred vision blurred vision, swelling or pain, or having halos appear around lights;
  • Unusual bone pain or tenderness, bleeding, swelling, or bruising
  • Changes in appetite or weight;
  • Simple bruising bleeding that is unusual (nose, vagina, mouth, or rectum) bleeding from the mouth, nose, vagina, or rectum;
  • Extremely rigid (rigid) muscles and a high fever. Sweating and confusion; rapid or irregular heartbeats; tremors; fainting; or
  • Low levels of sodium in the body. Headache headache, confusion, inability to speak, severe weakening, a loss in coordination, and feeling unstable.

Get medical attention immediately. If you experience signs associated with serotonin syndrome, for example, hallucinations, agitation, sweating or shivering, an increase in heart rate, stiffness of muscles and twitching, nausea, vomiting, diarrhea, or nausea,

Common adverse effects of Pexeva include:

  • Vision change;
  • Weakness, drowsiness, dizziness, and tiredness;
  • Sweating, anxiety, shaking;
  • Sleep problems (insomnia);
  • Insomnia, loss of appetite diarrhea, vomiting, constipation;
  • Dry mouth, chewing;
  • Infection;
  • Headaches migraine
  • Diminished sex drive, insanity, irregular ejaculation, or difficulty having an orgasm.

This is not a comprehensive list of possible side effects, and others could happen. Consult your physician for advice regarding medical effects. You can report symptoms to the FDA at 1-800-FDA-1088.


It is not recommended to make use of Pexeva in conjunction with already taking pimozide or thioridazine.

Do not take Pexeva in the 14-day period prior to or 14 days following the last time you used any MAO inhibitor, for example, linezolid, isocarboxazid or methylene blue injection, or phenelzine rasagiline and selegiline, or tranylcypromine.

A few young people may have thoughts of suicide while using an antidepressant. Keep vigilant for any changes in your attitude or symptoms. Be sure to report any new or deteriorating symptoms to your physician.

You should seek medical attention immediately if you experience symptoms that include: hallucinations, agitation, muscle stiffness, twitching disorientation, loss of coordination, sensation of warmth or tingling, nausea, vomiting, sweating, diarrhea or tremors, heartbeats racing, or seizures (convulsions). Do not stop taking Pexeva without first consulting your physician.

Before you start taking this medicine

You shouldn't make use of Pexeva in the event that you have an allergy to Pexeva or are also taking pimozide and thioridazine.

Do not take an MAO inhibitor for 14 days prior to or 14 days following the time you took Pexeva. A potentially dangerous interaction with a drug could occur. MAO inhibitors are isocarboxazid rasagiline, linezolid, phenelzine selegiline, tranylcypromine, and so on. Once you have stopped taking this medication, you should wait at least 14 days before deciding to begin taking the MAO inhibitor.

Inform your doctor if you have ever suffered from:

  • Heart diseases, high blood pressure, or stroke;
  • Kidney or liver disease;
  • A bleeding or blood clotting disorder;
  • Seizures or epilepsy;
  • Bipolar disorder (manic depression), drug addiction, or suicidal thoughts
  • Sexual issues;
  • Narrow-angle glaucoma; or
  • Low levels of sodium in your blood.

Check with your physician whether you are also taking stimulant medicines, opioid medications, herbal products, or medicines to treat mental illness, depression, Parkinson's disease, migraine headaches, serious infections, or for the prevention of vomiting and nausea. These medications can interfere with Pexeva and trigger a severe serotonin-related disorder.

A few young people may have thoughts of suicide while first starting an antidepressant. Your doctor should monitor your progress on a regular basis. Your family members and other caregivers should be aware of changes in your symptoms or mood.

The use of an SSRI antidepressant during pregnancy could result in serious lung issues or other issues for the infant. You could also experience a relapse of depression when you quit using your antidepressant. Inform your doctor immediately when you find yourself pregnant. Do not begin stopping this medication without consulting your physician. Do not use Brisdelle if you are pregnant. It is recommended not to breastfeed when taking this medication. i am 18 years old.

How to take Pexeva?

Follow the directions on the prescription label and read the medication guide or instructions sheets. Your doctor may change the dosage. Make sure you take the medication precisely as prescribed. Take this Extended-Release tablet in its entirety, but do not crush, chew, or break it. shake it up in oral suspension (liquid) prior to using it to take a dosage. Make use of the dosing syringe supplied or a dosage-measuring device (not the kitchen spoon). It could take as long as 4 weeks before symptoms improve. Use the medication exactly according to the directions, and inform your physician if your symptoms don't improve. Consult your physician if you are experiencing any changes in your sexual activity, like the loss of interest in sex and difficulty having an orgasm, or (in males) issues with erections or ejaculation. There are some sexual problems that are treatable. Don't stop taking Pexeva in a hurry; otherwise, you might experience uncomfortable withdrawal effects. Discuss with your physician how you can completely stop taking this medicine. Follow your doctor's advice on the process of tapering your dose. Maintain at room temperature, far from heat, humidity, and light.

Do I be concerned if I miss a dose?

Do not take the medicine for as long as you are able, but do not take your missed dosage if it's close to the time of the next dose. Don't take two doses at a time.

What will happen if I take excessively?

For medical emergencies, seek emergency treatment or contact the Poison Help Line at 1-800-222-1222. A fatal overdose of Pexeva can cause death.

What should be avoided?

Avoid driving or engaging in hazardous activities until you understand how Pexeva can affect you. The way you react could be affected.

Consult your physician before using a nonsteroidal anti-inflammatory medication (NSAID) like Ibuprofen, aspirin (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, and meloxicam, among others. When you take an NSAID along with Pexeva, it can cause bleeding or bruises easily. Alcohol consumption with this medicine may cause unwanted side effects.

Interaction with other drugs

Utilizing Pexeva along with other drugs that cause drowsiness can increase the severity of this effect. Consult your physician before taking opioids, sleeping pills, muscle relaxers, or medication to treat seizures or anxiety.

Discuss with your doctor any other medications you take, particularly:

  • Cimetidine (Tagamet), digoxin, St. John's wort, tamoxifen theophylline, tryptophan (sometimes called L-tryptophan), warfarin (Coumadin, Jantoven);
  • A diuretic, or "water pill";
  • Heart rhythm medicine;
  • HIV, also known as AIDS medicines,
  • Certain medications for treating the symptoms of ADHD or narcolepsy, such as atomoxetine, dextroamphetamine, Adderall, Dexedrine, Evekeo, Vyvanse, and others;
  • Narcotic pain medicine—fentanyl, tramadol;
  • Medication to treat mood disorders, thoughts disorders, and mental illnesses, such as buspirone, lithium, and various antidepressants, as well as an antipsychotic;
  • Migraine headache medicine—sumatriptan, rizatriptan, zolmitriptan, and others; or
  • Seizure medicine—phenobarbital, phenytoin.

This list isn't complete. Other medications can interact with paroxetine. This includes medications that are prescribed and available over the counter, vitamins, and herbal supplements. The interactions of all potential drugs are mentioned in this medication guide.