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Parnate

Name of the Generic: Tranylcypromine ([TRAN-il-SIP-roe-meen]). TRAN-il SIP-roe meen [TRAN-il-SIP-roe-meen]
Drug Class: Monoamine oxidase inhibitors

What is Parnate?

Parnate is a monoamine oxidase inhibitor (MAOI), which is a drug that increases the levels of certain chemical substances in the brain.

Parnate can be used to treat major depression episodes in adults when other treatments haven't been efficient.Parnate is also employed for other purposes that are not covered in this guideline.

Side effects of Parnate

Contact a medical professional immediately. If you are experiencing symptoms that are warning signs of an allergic response, like hives, trouble breathing, or swelling of your lips, tongue, throat, or face,

Inform your doctor about any new or deteriorating symptoms for treatment, including changes in your behavior or mood, anxiety, panic attacks, trouble sleeping, or if you experience being angry, irritable, impulsive, or aggressive. anxious, hyperactive (mentally as well as physically), depressed, contemplating suicide, or causing harm to yourself.

Parnate could cause severe adverse effects. Contact your physician immediately if you experience:

  • Dilation of the pupils, problems with vision, and sensitivity to light
  • A sudden and intense severe and sudden headache, neck pain, or stiffness;
  • Weakness or numbness; issues with speech or vision;
  • Heartbeats that are fast or rapid;
  • Fever, cold sweat, nausea, vomiting;
  • A feeling of lightheadedness, as if you're passing out;
  • A seizure;
  • Manic episodes: racing thoughts, higher energy levels, less need for sleeping, taking risks, talking, or being angry;
  • Serotonin levels are high in the body, causing anxiety, hallucinations, sweating and shivering, muscle stiffness, and twitching. It can also cause loss of coordination, diarrhea, vomiting,
  • Problems with the liver: loss of appetite, stomach discomfort (upper right side) Dark color of urine; jaundice (yellowing of the eyes or skin).

The risk of serious side effects is higher in older adults.

Common adverse effects of parnate can include:

  • Dizziness, drowsiness;
  • Constipation;
  • Dry mouth, blurred vision
  • Difficulty sleep;
  • Headaches;
  • Feeling shaken or excited.

The following isn't an exhaustive listing of all possible adverse reactions, as other reactions could be experienced. Consult your physician for advice regarding medical effects. You can report any symptoms to the FDA at 1-800-FDA-1088.

Similar/related drugs

Rexulti, Trintellix, Sertraline, Trazodone, Lexapro, Citalopram, and Zoloft

Warnings

Many young people are contemplating suicide after using an antidepressant. Keep vigilant for changes in your attitude or symptoms. Inform your doctor if you notice any changes or worsening symptoms.

There are a variety of other foods, drugs, and drinks that can cause serious health issues in the event that you combine them in conjunction with Parnate. Tell your doctor about all of your medications and any that you decide to stop or begin using. Beware of drinking alcohol and be aware of the foods you should stay away from.

Foods that contain high levels of tyramine and Parnate could result in extremely high hypertension. Symptoms include an acute and sudden headache, nausea, vomiting, dilation of the pupils, a cold sweat, or light sensitivity. They may also experience rapid heartbeats, neck stiffness, weakening, or issues in speech or vision.

Before you take this drug

You shouldn't take Parnate if you are allergic to its ingredients or suffer from:

  • Pheochromocytoma (a tumor that affects the adrenal gland)

A risky drug interaction can be triggered between Parnate and other medications that you've used in the last 14 days. Avoid using this medication in conjunction with:

  • Other antidepressants
  • Buspirone, carbamazepine, reserpine, tapentadol, tetrabenazine, tryptophan, and SAM-e;
  • Diet pills and stimulants ADHD medication, cough and cold medicine, or allergy medicine;
  • Serotonin-related drugs can alter the levels within your body. These include stimulant medications and opioids, herbal products or medications that treat depression, illnesses of the mind, Parkinson's disease, migraine headaches, severe infections, or the prevention of vomiting and nausea.

Inform your doctor if you have ever suffered from:

  • Heart condition: hypertension or low blood pressure blood circulation issues and stroke;
  • Bipolar disorder (manic depression);
  • The liver condition;
  • An thyroid disorder;
  • Headaches;
  • Diabetes (Parnate could result in lower blood sugar)
  • A seizure.

A few young people may have thoughts of suicide after first starting an antidepressant. Your doctor should be able to check your progress regularly. Your family members and other caregivers should be on the lookout for changes in your mood or symptoms.

Parnate can cause harm to an unborn baby. Tell your doctor whether you are pregnant or if you find yourself pregnant.

It is not recommended to breastfeed when using Parnate.Parnate is not suitable for use by anyone less than 18 years old.

How to take Parnate?

Follow the instructions on the prescription label and go through all medication guides or instruction sheets. Your doctor may change the dosage. Follow the medication precisely as directed.Your blood pressure needs to be checked regularly.

It is possible that you will need to stop taking Parnate for a brief period prior to any procedure or other medical treatment. Inform any physician who treats you that you are taking this medication.It could take a few weeks before you get the full benefit from taking Parnate. Your physician will decide the time frame for treatment using Parnate.

Do not stop taking Parnate abruptly, or you may experience painful withdrawal signs. Consult your physician about how you can completely stop taking this medication.Maintain room temperature and free of moisture and heat.

What happens If I miss a dose?

Do not take the medicine for as long as you can. However, do not take your missed dose if you are nearing the time to take the next dose. Don't take two doses at a time.

What happens if I overdose?

For medical emergencies, seek immediate attention. Or contact emergency medical attention or call the Poison Help line at 1-800-222-1222. Some symptoms of an overdose may be characterized by feeling anxious or restless, insomnia, sleep issues, confusion, agitation, fatigue, severe headaches, neck stiffness or pain, pounding heartbeats, or loss of consciousness.

What should be avoided?

Avoid drinking alcohol. Dangerous side effects may be experienced.

It is not recommended to eat foods high in tyramine, such as:

  • Air-dried and aged meats, such as sausage or salami
  • Tap water (not in bottles or cans);
  • Pickled herring
  • Aged cheeses, which include blue Brie, Boursault, and brie camembert cheese; cheddar; gruyere mozzarella; parmesan Romano; Roquefort; and Swiss;
  • The meat may be rotten or stored improperly, or the poultry or liver may be
  • Miso soup, miso sauce beans curd, fava beans, as well as
  • The yeast extracts Marmite.

Tyramine consumption while taking Parnate can increase the blood pressure to dangerous levels, leading to life-threatening consequences. Avoid tyramine for two weeks after stopping this medication.

Avoid driving or engaging in hazardous activities until you are aware of how Parnate affects you. Your reaction could be affected.

Interaction with other drugs

If you stop or begin taking Parnate, the doctor might have to alter the dosages of any other medication you take on a daily basis.

There are numerous other medications that could cause serious medical issues in the event that you combine them with Parnate. This includes medications that are prescribed and available over the counter, vitamins, and herbal remedies. The interactions of all drugs are included in this guide to medication. Tell your doctor about all the medications you are currently taking as well as any medications you are about to start or stop taking.

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Prescription only

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