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Generic Name: Peginesatide [PEG-in-ESA-tide].

 Drug Class: Recombinant human-derived erythropoietins.

What are Omontys?

Omontys is a synthetic form of a protein that helps your body produce red blood cells. The quantity of this protein in your body can be decreased when you suffer from kidney disease or are taking certain medicines. If fewer red blood cells get made, it can lead to anemia.

Omontys helps treat anemia (an insufficient supply of blood red cells within the body) for patients suffering from chronic kidney disease taking dialysis. Omontys is not a treatment for anemia due to other illnesses. This medication is not intended to be used by those who aren't taking dialysis. Omontys could also be used to treat conditions that aren't listed in this guide.


It is not recommended to take Omontys in the event that you are allergic to peginesatide or suffer from untreated or uncontrolled high blood pressure. Before you start using Omontys, tell your doctor if you suffer from cardiac disease, congestive failure, high blood pressure, cancer, seizure disorders, a blood cell bleeding disorder (such as hemophilia or sickle cell disease), or have a history of stroke, heart attack, or a blood clot. Other doses of your medication might need to be adjusted once you have started taking Omontys. Discuss with your doctor the medications you take.

To make sure that Omontys is helping with your health, your iron levels and blood cells will have to be monitored regularly with regular blood tests. Your blood pressure will require regular monitoring. Visit your doctor regularly. See your doctor if you feel lightheaded, weak, or breathless, or if you notice that your skin appears pale. This could indicate that your body is not reacting to the medication. Omontys may increase your chance of developing life-threatening heart or circulation issues, including stroke or heart attack. The risk of having a stroke or heart attack increases the longer you take Omontys. Contact a doctor immediately when you experience symptoms of a heart or circulation problem that include sudden chest pain, numbness, weakness, or a severe headache; issues in speech or vision; a sudden cough that is coughing up blood; discomfort or warmth in your legs; a cold or tingly sensation like you're not breathing; rapid weight gain; or issues with the hemodialysis vein you access.

Similar/related drugs

ferrous sulfate, FeroSul, Aranesp, Procrit, and Retacrit

Before you take this drug

Omontys is not recommended. If you have an allergy to peginesatide or suffer from untreated or uncontrolled high blood pressure. To ensure you can safely take Omontys, be sure to tell your doctor if you have any of the following other medical conditions:

  • Heart disease, congestive heart failure, and hypertension (hypertension).
  • A history of stroke or an attack on the heart, or a blood clot.
  • A blood cell disorder or an underlying clotting disorder, like hemophilia or sickle cell anemia.
  • Cancer.
  • Epilepsy, or any other seizure disorder.

FDA classification for pregnancy C It is unclear whether Omontys can harm an unborn baby. Consult your physician if you are expecting or planning to get pregnant while taking the medication. It is unknown if peginesatide is absorbed into breast milk or if it is harmful to nursing babies. Do not take Omontys without consulting your physician, whether you breastfeed your baby or not.

How to take Omontys?

Utilize Omontys precisely as directed by your physician. Avoid using in larger quantities, in smaller amounts, or for longer periods than prescribed. Follow the instructions on the label of your prescription. mOmontys is injected underneath the skin or via an IV. It is possible to be taught how to inject an IV at home. Don't self-inject the medicine if you don't fully know how to administer the injection or how to dispose of the IV tubing, IV needles, and other equipment that you use to inject the medicine. Omontys is typically given every month. Follow your doctor's dosage instructions with care. The doctor might change the dosage to ensure you are getting the best results. The syringes that are prefilled and the one-time bottle (bottle) in this medication are intended for one usage only. Toss it away after just one dose, regardless of whether there's still some medication left after you have injected your dose.

Avoid using Omontys in the event that it has changed color or has particles. Consult your physician for a new prescription. Use a disposable needle only once. Recycle needles used for disposal in a container that is puncture-proof (ask your pharmacist where to get one and the best way to eliminate it). Make sure this container is out of the reach of animals and children. To ensure that this medication is working for you, your iron levels and blood cells need to be inspected regularly through blood tests. Your blood pressure will require regular monitoring. Visit your doctor regularly. If you are undergoing surgery, tell your surgeon in advance that you're using Omontys. Omontys is only a part of a full treatment program that may also involve diet and taking blood pressure medications. Make sure you follow your medication and diet regimen extremely closely. Omonty's dosages are based on weight. Inform your doctor if you notice an increase or decrease in weight. Storage: Omontys in the original container in the refrigerator. Do not freeze. Keep away from sunlight. If required, the medication can be kept at room temperature for as long as 30 days. Don't use this vial (a bottle that has multiple doses contained in it) for more than 28 days following the first time you put needles inside the vial. The vial should be thrown away even if there's still some medication in it after 28 days.

What happens if I miss a dose?

Utilize the missed dose immediately when you remember. You can then resume your daily dosing schedule and take the subsequent dose 30 days later. Do not take extra medication to replace the dose you missed.

What happens if I overdose?

Get medical attention in an emergency or contact the Poison Help line toll-free at 1-800-222-1222.

What should be avoided?

Follow the doctor's advice regarding any restrictions on your food, drink, or activity.

Adverse negative effects of Omonty

See a doctor immediately. If you notice any of the following symptoms that indicate an allergy reaction, Omonty's symptoms: hives; trouble breathing; or swelling of your lips, face, or tongue. Consult your physician if you are feeling weak, lightheaded, or short of breath, or if you notice that your skin appears pale. This could indicate that your body is not reacting to the medication. Omontys may increase the risk of having life-threatening heart circulation issues, such as stroke or heart attack. The risk increases the longer you take Omontys.

Get medical attention immediately for any signs of heart or circulation issues, for example:

  • Chest pain or a heavy feeling in the chest; pain spreading into the shoulder or arm; nausea; sweating; a general feeling of discomfort.
  • A sudden sensation of weakness or numbness in one area of the body.
  • Sudden, severe migraine, confusion, or problems with speech, vision, or balance.
  • Chest pain, a sudden cough, wheezing, rapid breathing, and coughing up blood.
  • The sensation of warmth, pain, swelling, or redness in one or both legs.
  • Numbness, a tingling, chilling sensation, or a pale appearance in your legs or arms.
  • Feeling breathless and short of breath, even when exerting only a little.
  • Swelling and rapid weight gain.
  • Fainting, feeling lightheaded, or fainting.
  • If the hemodialysis vein ceases to function.

Contact your doctor immediately. If you suffer from other serious adverse effects, like:

  • Simple bleeding, unusual bruising (nose, vagina, mouth, or rectum), and red or purple small spots on your skin.
  • Fainting and feeling lightheaded.
  • Pale skin, feeling tired, fast heart rate, difficulty concentrating.
  • Excessive levels of potassium (a slow pulse, a weak pulse, and the sensation of tingling).
  • Fever.
  • Seizure (convulsions).
  • Extremely high blood pressure (severe headache, blurred vision, a ringing in your ear, confusion, anxiety, chest discomfort, breathlessness, irregular heartbeats, seizures).

Less severe Omontys side effects can include:

  • Nausea, vomiting, diarrhea.
  • Headache.
  • Cough.
  • Lower back pain or muscle spasms, arm pain, or legs.
  • Joint pain.
  • Cold symptoms like congestion, sneezing, and a sore throat.

This isn't an exhaustive list of all the side effects. Other side effects could occur. Consult your physician for advice regarding medical effects. You can report any side effects to the FDA at 1-800-FDA-1088.

What other drugs can alter Omontys?

There could be other drugs that interfere with Omontys. Other doses of your medication might need to be adjusted once you have started taking Omontys.

Inform your doctor about any medications you use. This includes prescription, over-the-counter or vitamin products, as well as herbal products. Do not begin an entirely new drug without consulting your physician.