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Generic Name: Naratriptan [NAR-a-TRIP-tan]
Name of the Brand: Amerge
Dosage Format: Oral tablet (1 mg; 2.5 mg)
Drug Class: Antimigraine agents

What is Naratriptan?

Naratriptan can be described as a headache medication that reduces blood vessels in the brain. Naratriptan also decreases the amount of substances within the body that can cause headaches, sensitivity to sound and light, and other symptoms of migraine.

Naratriptan is a medication used for migraine treatment. Naratriptan can only be used to treat headaches that have already started. It is not able to help prevent headaches or lessen the frequency of attacks.

Naratriptan is not a suitable medication to treat common tension headaches, headaches that cause a loss of movement on the opposite or other side, or any other headache that appears to be distinct from your regular migraine headaches. Only use naratriptan when your condition is confirmed by a medical professional for migraine headaches.Naratriptan is also employed for reasons not mentioned in this guideline.

Side effects of Naratriptan

See a doctor immediately. Get medical attention immediately if you notice symptoms that are warning signs of a reaction, such as difficulty breathing, hives, and swelling of your lips, face, and tongue.

Naratriptan may cause serious side effects. Stop taking Naratriptan and notify your physician immediately. If you suffer from:

  • Heartbeats that are fast or rapid;
  • Numbness or tingling, as well as an appearance of blue or paleness in your toes and fingers;
  • The feeling of pain or heaviness in your legs and hips. It is also possible to feel the sensation of burning in your feet.
  • Acute stomach pain bloody diarrhea, constipation, fever, weight loss;
  • Extremely excessively high blood pressure—severe headache, fuzzy vision, the sound of a pounding inside your neck or ear, nosebleeds, anxiety, chest pain that is severe, shortness of breath, and irregular heartbeats. seizures;
  • Heart attack symptoms: chest pressure or pain; pain expanding into your shoulder or jaw; nausea; sweating;
  • Serotonin levels that are elevated in the body cause anxiety and hallucinations. Fever, fast heart rate, excessively active reflexes, vomiting, loss of coordination, diarrhea, fainting,
  • Symptoms of signs of stroke—sudden weakening or numbness (especially for one leg) or a sudden and extreme headache, speech lisping, or issues with balance or vision.

Common negative side effects of naratriptan include:

  • Dizziness, drowsiness;
  • Being tired or weak;
  • Numbness or tingling
  • Flushing (warmth, redness, or tingling sensation);
  • Nausea;
  • Discomfort or tightness in your neck, jaw, or throat.

This isn't a complete list of all the side effects. Other effects may also be present. Contact your physician for advice regarding medical effects. You can report any side effects to the FDA at 1-800-FDA-1088.


Naraptan should not be used when you suffer from excessively high blood pressure, heart conditions, certain heart rhythm disorders, severe kidney disease, or a history of heart attack, stroke, or circulatory issues that lead to a deficient blood supply inside the body.

Take naratriptan within 24 hours of taking an alternative headache or migraine medication.

Before you take this drug

This medication is for you if you have an allergy to naratriptan or you suffer from:

  • Uncontrolled or severe high blood pressure
  • Current or past heart issues;
  • The history of the coronary artery, heart attack, or stroke, which includes "mini-stroke";
  • Wolff-Parkinson-White syndrome or other heart rhythm disorder
  • A blood vessel disorder or circulatory problems that result in an absence of blood supply in the body.
  • Severe kidney or liver disease severe kidney or liver disease
  • A headache that is distinct from the usual migraine headache.

To ensure that naratriptan is suitable for you, inform your physician if you suffer from:

  • Kidney or liver disease
  • Hypertension, a heart rhythm disorder,
  • Coronary heart illness (or risk factors like menopause, diabetes, being overweight, having a high cholesterol level, having an ancestral background of coronary disease, being over 40 years old, and being a male or female who underwent an operation to remove her uterus)

It isn't known if this medication could cause harm to a baby who is not yet born. Consult your physician if you are expecting or planning to become pregnant.

It is unclear if it is possible to introduce naratriptan into breast milk or if it can harm nursing babies. It is not recommended to breastfeed when taking this medication.Don't give the medication to anyone who is younger than 18 years of age.

How to Take Nartriptan?

Your doctor might provide the first dose of Naratriptan in the setting of a clinic or hospital to treat any adverse side effects that may be experienced.

Follow all the instructions on the prescription label. Do not exceed your recommended dosage. In excess, migraine headache medication can cause more headaches. Inform your doctor if the medicine isn't working properly for treating migraine headaches.Start taking naratriptan as soon as you begin to notice symptoms of migraine.

Take one tablet whole and drink a full glass of water.After taking tablets: If your headache doesn't completely disappear or is gone only to come back, call your doctor prior to taking another tablet.

Do not take a second tablet until 4 hours have passed since you last took your first pill. Do not exceed five milligrams (mg) of naratriptan over 24 hours.If your symptoms haven't been alleviated after taking two tablets within 24 hours, you should consult your physician prior to taking additional tablets.Inform your doctor if you suffer from multiple headaches during the course of a month (30 days).

Naratriptan could elevate blood pressure to potentially dangerous levels. The blood pressure of your patients may require frequent monitoring during the course of using this medication. If you take naratriptan over a long period of time, your heart function could require a check with an electrocardiograph, also known as an ECG (sometimes known as the EKG).Keep at room temperature, free of heat, moisture, and light.

Details on dosage

Usual Adult Dose for Migraine:

Use it only after a specific medical diagnosis has been made.
Initial dose: 1 mg or 2.5 mg orally at least once.
If there was a reaction to the initial dose, a subsequent dose could be administered for at least 4 hours if the migraine recurs or symptoms persist.
Maximum dose: 5 mg in a 24-hour period
This medication should not be used to treat hemiplegic or basilar migraines since these sufferers are more at risk of stroke.
The effectiveness of treating four plus migraines within 30 days has not been confirmed.
Use: To treat the acute treatment of migraine, with and without aura.

What happens if I miss the dose?

Because naratriptan is only used when necessary, it does not have a regular dosing schedule. Contact your doctor if symptoms don't improve following the use of the drug.

What happens If I overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

The symptoms of an overdose can include fatigue, neck stiffness, loss of coordination, or feeling lightheaded.

What should be avoided?

Don't take Naratriptan for the next 24 hours after using a different migraine headache medication, such as:

  • Medicines like naratriptan—almotriptan, eletriptan, frovatriptan, rizatriptan, sumatriptan, zolmitriptan, and others;
  • Ergot medicine: dihydroergotamine, ergotamine, ergonovine, and methylergonovine.

Naratriptan can impair your ability to think or react. Be cautious when driving or doing any activity that requires you to remain vigilant.

Interaction with other drugs

If you take naratriptan when taking other medications, the levels of serotonin can accumulate within your body, an issue known as "serotonin syndrome that can lead to death. Consult your physician when you are also taking:

  • Medication used to manage the symptoms of depression;
  • Medication for treating the symptoms of a mental disorder;
  • A drug called a narcotic (opioid) medicine;
  • Medicine to reduce nausea or vomiting.

This list isn't complete. Other medications can interact with naratriptan. This includes prescription and over-the-counter medicines, vitamins, and herbal products. The interactions of all potential drugs are mentioned in this medication guide.



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