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Naprelan 500

Name of the Generic: Naproxen [Na-PROX-en] [na-PROX-en]
Names of Brands: Aleve, Aleve Back and Muscle Pain, Aleve Easy Open Arthritis, Aleve Liquid Gels, Anaprox-DS… Show the 10 brands.
Class of Drug: Nonsteroidal anti-inflammatory drugs

What is Naprelan 500?

Naprelan 500 is one of the drugs that have a nonsteroidal anti-inflammatory effect (NSAID).Naprelan 500 can be used to treat inflammation or pain due to conditions like arthritis, ankylosing spondylitis, tendinitis, bursitis, gout, or menstrual cramps.

Extended-release or delayed-release tablets are slower-acting versions of naproxen that are only used for chronic conditions like arthritis and ankylosing spondylitis. The forms of naproxen listed above are not effective enough to relieve acute pain.Naprelan 500 can be used for other purposes that are not mentioned in this guide.

Side effects of Naprelan 500

Seek medical attention immediately. If you notice symptoms that are warning signs of an allergic reaction (runny or stuffy noses, wheezing, difficulty breathing, hives, swelling of your throat or face) or an extreme skin reaction (fever and sore throat, eye burning, irritation, and red or purple skin itching that blisters and peels),

Stop taking Naprelan 500. Seek medical assistance when you experience a severe drug reaction that could affect the body in a variety of ways. Symptoms may include the appearance of a rash on your skin or fever, swelling of the glands, muscle pains, abnormal bruising, severe weakness, or the yellowing of your eyes or skin.

Take immediate medical care. If you are experiencing symptoms of a stroke or heart attack, such as chest pain spreading to your shoulder or jaw, suddenly feeling numb or weak in one area of your body, slurred speech, leg swelling, or feeling short of breath,

Naprelan 500 can cause severe adverse consequences. Take a break from Naprelan 500 immediately and contact your doctor immediately in the event that you experience:

  • Breathlessness (even at moderate exertion);
  • Rapid weight loss or swelling
  • The initial sign of a skin rash or blister, regardless of its severity;
  • Indications of stomach bleeding: bloody or black stools; the spouting of the blood; or vomit that appears like coffee grounds.
  • Liver issues liver problems: nausea and stomach pains in the upper region nausea, appetite loss, black stools, dark urine, jaundice (yellowing of the eyes or skin),
  • Kidney issues: no or little urinary frequency, painful urination, swelling in your feet and ankles;
  • Low red blood cells (anemia)—pale skin, uncharacteristically tired and feeling lightheaded or sluggish, cold hands and feet

Common negative side effects of Naprelan 500 include:

  • Headache;
  • Indigestion, heartburn, stomach pain;
  • Flu symptoms;

It isn't a complete listing of all adverse negative effects. Other conditions could occur. Ask your physician for medical advice regarding the consequences. If you have any concerns, report the symptoms to FDA by calling 1-800-FDA-1088.


Naprelan 500 may increase your risk of a fatal cardiac attack as well as a stroke. Avoid using Naprelan 500 before or following coronary bypass surgery (coronary bypass graft to the artery, also known as CABG). This medicine can cause bleeding from the stomach or in the intestinal tract that could be fatal.

Before you take this drug

Naprelan 500 may increase your risk of having a fatal heart attack or stroke even if there isn't an underlying risk factor. Don't take this medication immediately prior to or after the procedure for heart bypass (coronary bypass grafts, or CABG).

Naprelan 500 can cause diarrhea or stomach bleeding, which can lead to death. These issues can happen at any time while taking this medication and are more common among older adults.

It is not recommended to use Naprelan 500 if you are allergic to it or have had one asthma attack or a severe allergic reaction following using aspirin or an NSAID.Talk to your doctor prior to giving Naproxen 500 to a baby less than twelve years of age.

Consult your doctor or pharmacist to determine if this medication is safe to use if you are suffering from:

  • Coronary disease, high blood pressure, high cholesterol, diabetes, or if you smoke
  • A stroke, heart attack, or blood clot
  • Stomach ulcers, bleeding, or bleeding
  • Asthma;
  • Kidney disease or liver failure;
  • Fluid retention;
  • If you are taking aspirin to stop heart attacks or strokes.

If you're pregnant, then you shouldn't take Naproxen 500 until your doctor has told you not to. Taking an NSAID in the final twenty weeks of pregnancy may result in serious kidney or heart issues in the baby and may cause complications during the pregnancy.

It might not be safe to breastfeed while taking this medication. Consult your physician regarding any risks.

How to Take Naprelan 500?

Take it exactly as indicated on the label or as recommended by your physician. Choose the dose that will be effective in treating your illness.Make sure to shake off the oral suspension (liquid) prior to taking a dosage. Take a dose using the measuring device supplied (not an ordinary spoon).Take Naproxen 500 with milk or food in the event that it upsets your stomach.

Follow the instructions on the medication label regarding the dosage of this medication for children. Naprelan 500 dosages are determined by the weight of children. The dose requirements of your child could be altered if they gain or lose weight.If you are using Naproxen 500 for a long time, it could be necessary to have regular medical examinations.

This medication may affect the outcomes of certain medical tests. Inform any physician who treats you that you're taking Naprelan 500.Keep the bottle at room temperature, away from heat, humidity, and light. Make sure the bottle is tightly shut when not in use.

What happens If I miss a dose?

Because Naprelan 500 is only used in the event of need, you might not be following a dose schedule. Don't miss a dose when it's time to take the next dose. Don't take two doses at once.

What happens If I overdose?

Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.

What should be avoided?

Do not drink alcohol. This can increase the chance of bleeding from your stomach.Do not take aspirin or similar non-steroidal antidotes except if your physician has told you to.

Talk to your doctor or pharmacist prior to using any other medications for swelling, pain, fever, or other symptoms of the cold or flu. They could contain ingredients similar to Naprelan 500 (such as aspirin, ibuprofen, or ketoprofen).

Consult your physician before taking an antacid. Make sure you use only the one that your doctor recommends. Certain anti-inflammatory medications could make it more difficult for your body to process Naproxen 500 mg.

Interaction with other drugs

Talk to your doctor before taking Naproxen 500 if you're taking medication for depression. Taking certain antidepressants along with an NSAID could cause bleeding or bruises.

Speak with a pharmacist or doctor before taking Naproxen 500 along with other medications, particularly:

  • Other NSAIDs and other salicylates (diflunisal, salsalate);
  • Antacids and sucralfate;
  • Cholestyramine;
  • Cyclosporine;
  • Digoxin;
  • Lithium;
  • Methotrexate;
  • Pemetrexed;
  • Probenecid;
  • Warfarin (Coumadin, Jantoven) or other blood thinners similar to it;
  • Diuretic, also known as "water pill";
  • Heart or blood pressure medications

This list isn't complete. Other drugs can interact with Naproxen 500, such as prescription and over-the-counter medicines, vitamins, and herbal supplements. Some interactions with drugs are not listed here. are included here.



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