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Mitosol

Generic name: mitomycin ophthalmic [MYE-toe-MYE-sin-off-THAL-mik]
Drug class: Miscellaneous ophthalmic agents

What is Mitosol?

Mitosol, an antimetabolite medication, interferes with certain cell growth in the body.

Mitosol can be used in glaucoma surgeries.

This medication guide does not list all possible uses of mitosol.

Warnings

If you're pregnant, it is not recommended that Mitosol be used.

Before you take this drug

If you have an allergy to mitomycin, then mitosol should be avoided.

Do not use Mitosol while pregnant or thinking you might be pregnant. Mitomycin can harm an unborn child or cause a birth defect.

Before taking Mitosol, inform your physician of all of your allergies and medical conditions as well as medications you are currently taking. In particular, be sure to notify him or her of your pregnancy status or breastfeeding status.

There is no way to know if mitomycin passes through breast milk or if it can harm nursing babies. After receiving mitomycin, you should not nurse your baby. Listen to your doctor about when you can resume breastfeeding after treatment.

How to take Mitosol?

When you have glaucoma, your healthcare provider may apply Mitosol directly to the eye.

Glaucoma surgeries are usually done while the patient is awake. You'll be prescribed medicine to reduce any pain and discomfort you may feel during the surgery.

You will be asleep during your operation if you are under general anesthesia.

Mitosol, a liquid medication, is first applied to a tray containing tiny sponges. The mitomycin will be soaked into the sponges for 60 minutes.

Your surgeon will apply the mitomycin-soaked sponges to your eye directly after they have been saturated.

After 2 minutes, the sponges are removed.

Your eye will then be thoroughly rinsed after the sponges have been removed.

After surgery, your doctor may prescribe you other eye medicines. All medications should be taken as prescribed. Each medication comes with a patient instruction guide or medication guide. You should not alter your medication or dose schedule without consulting your doctor.

Details on dosage

Adult dose for glaucoma:

The surgery is an addition to the ab externo glaucoma procedure.

Mitomycin 0.2 mg is in the sponges supplied with the kit. Use surgical forceps to apply the fully saturated sponges in one layer to the area being treated. Hold the sponges in place for at least two (2) minutes.

What happens if I miss the dose?

You are unlikely to miss any doses because you'll be receiving this medication in a clinic setting.

What happens if I overdose?

Mitosol will be administered by healthcare professionals in medical settings, so an overdose of the drug is not likely to happen.

What should be avoided?

You should only use eye drops if your doctor prescribes them.

Side effects of Mitosol

If you experience any of the following symptoms of an allergic response to Mitosol, seek immediate medical attention: itching, difficulty breathing, swelling in your lips, face, throat, or tongue.

If you experience:

  • Blurred vision, vision loss;
  • Tunnel vision is a condition that causes eye pain and halo-like effects around light sources.
  • Eye swelling, discomfort, crusting, or drainage may be an indication of infection.

Mitosol can cause a variety of side effects.

  • Eye redness;
  • Vision changes

There may be other side effects. For medical advice on side effects, call your doctor. Report side effects by calling the FDA at 1-800-FDA-1088.

Interaction with other drug

Mitomycin in the eye is unlikely to interact with other medications you may take. Many drugs interact. Inform your doctors about any and all medications you take, including vitamins and herbal remedies, prescriptions, and over-the-counter medicines.