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Lidocaine injection

Generic name: lidocaine injection [LYE-doe-kane]
Brand names: Xylocaine HCl, Xylocaine MPF Lidoject 1, Xylocaine Dental Cartridges Lidoject 2,… Show all 13 brands.
Dosage forms: injectable solution (0.5%; 0.5% preservative-free; 1.5% preservative-free; 1%; 1% preservative-free; 2%; 2% preservative-free; 4% preservative-free; 5%-0.4%; 5%-0.8%),… show all 2 dosage forms
Drug Classes: Group 1 Antiarrhythmics Local Injectable Anaesthetics

What is a Lidocaine Injection?

Lidocaine can be used as a local anaesthetic to reduce the pain and discomfort that may result from invasive medical treatments. This includes surgery or needle punctures.Sometimes, lidocaine is used to treat irregular heartbeats that could indicate a possible attack.Lidocaine is also used in epidurals (spinal blocks) to relieve the pain of contractions.Lidocaine injections can be used in other ways than those listed in the medication guide.

Side effects of Lidocaine injection

If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: hives, difficulty breathing, swelling of the face, lips, or throat.

If you:

  • Twitching, tremors, seizure (convulsions);
  • Feeling light-headed, like you might pass out.
  • Slow heartbeat; weak pulse; shallow or weak breathing
  • Feeling of sudden heat, cold, or numbness
  • Muscle stiffness and pain
  • Weak or shallow breathing
  • Blue appearance of the skin
  • Unusual fear or anxiety is a sign of severe anxiety.

Side effects of lidocaine include:

  • Drowsiness, dizziness;
  • Nausea, vomiting;
  • Feeling hot or cold
  • Double vision, confusion, ringing ears, or blurred vision
  • The medicine accidentally applied to the skin can cause numbness.

There may be other side effects. Call your doctor for medical advice about side effects. To report adverse effects, you can contact the FDA at 1-800-FDA-1088.

Similar/related drugs

amiodarone, fentanyl, lidocaine, verapamil, flecainide, ketamine, and hyoscyamine


You should not receive a lidocaine injection if you have severe heart block or a heart rhythm disorder called Stokes-Adams syndrome or Wolff-Parkinson-White syndrome.

Before you take this drug

You should not take this medicine if you:

  • Heart block:
  • A heart rhythm disorder known as Stokes-Adams syndrome (sudden, slow heartbeats that cause you to faint);
  • A heart rhythm disorder called Wolff-Parkinson-White Syndrome (sudden fast heartbeats that can cause you to faint or become easily tired).

Tell your doctor about any of the following:

  • Allergy to Corn Products
  • Liver disease
  • Kidney disease
  • Heart disease
  • Coronary artery disease; circulation problems
  • Malignant Hyperthermia.

Tell your doctor whether you're pregnant or breastfeeding.

How to take lidocaine injectable?

This injection will be administered by a healthcare provider.Lidocaine is injected into the vein to treat problems with heart rhythm.Lidocaine is used to numb the area of the body that needs to be numbed. It's injected directly through the skin.While you receive a lidocaine infusion, your breathing, blood pressure, and oxygen levels will be closely monitored.Electrocardiograms (also called EKGs) are used to continuously monitor your heart rate if you have an irregular heart rhythm. This will allow your doctor to determine the length of time you should be treated with lidocaine.

What happens if I miss the dose?

You are unlikely to miss a dosage of lidocaine since it is only used in clinical settings.

What happens if I overdose?

Call 1-800-222-1222 for poison help or seek immediate medical attention.

What should be avoided?

Lidocaine injections may cause side effects that can impair your reactions or thinking. Do not drive unless absolutely necessary after receiving a lidocaine shot.After a lidocaine infusion has been used to numb the mouth or throat, you should not eat or chew within an hour. You could choke if you have difficulty swallowing. If you still feel numb after an hour of receiving lidocaine, it is possible that you may bite your insides.

Interaction with other drug

Tell your doctor about your other medications, including:

  • Cimetidine fluvoxamine nefazodone st john's wort
  • Antifungal or antibacterial medicine.
  • Antiviral medication to treat hepatitis, or hiv/aids.
  • Heart or blood pressure medicine—amiodarone, digoxin, nicardipine, procainamide, propranolol;
  • Seizure medicine—carbamazepine, phenytoin,
  • Tuberculosis medicine—isoniazid, rifampin

This list is incomplete. Lidocaine may be affected by other drugs, such as vitamins and herbs. This list does not include all drug interactions.