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Isovue-300

Generic name: iopamidol [eye-oh-PAM-ih-dol]

Brand names: Isovue-200, Isovue-250, Isovue-300, Isovue-370, Isovue-M-200, Isovue-M-300
Drug class: Non-ionic iodinated contrast media

What is the Isovue 300?

Isovue 300 is a radiopaque contrast agent (RAY DEE OOH PAYK). This medicine contains iodine, which is a substance capable of absorbing x-rays. The radiopaque contrast agent is used to make it easier to see blood vessels, organs, and non-bony tissue on a CT scan.

Isovue 300 is used to diagnose certain disorders affecting the brain, heart, blood vessels, and nervous system. This medication guide does not list all possible uses of Isovue 300.

Side effects of Isovue-300

If you experience symptoms of an allergic reaction, such as hives, difficulty breathing, swelling on your face or in your throat, or a severe reaction to your skin (fever or sore throat with burning, pain in the eyes, or skin rash, which is red or purple and blisters or peels), seek emergency medical attention.

If you experience a severe drug reaction, seek medical attention. This can include a skin rash, fever, or flu-like symptoms. Other symptoms may include muscle aches or weakness, unusual bruises, or yellowing.

Isovue 300 may cause serious side effects. If you experience:

  • Feeling faint and vulnerable.
  • Weight and fluid retention increase rapidly, yet there may be limited or no urinating.
  • Difficulty breathing
  • Seizure (convulsions);
  • You may experience swelling of the neck or throat.
  • Symptoms of thyroid disease include extreme tiredness, dry skin, stiffness or joint pain, muscle weakness or pain, hoarseness in voice, sensitivity to cold temperatures, and weight gain.
  • Heart attack symptoms: chest pain or pressure, spreading pain to your jaw and shoulders, nausea, or sweating.
  • Signs of a blood clot in the lungs: chest pain, sudden cough, shortness of breath, or coughing up blood
  • Signs of a stroke include sudden numbness and weakness, especially on one side; a severe headache or slurred speech; or problems with vision or equilibrium.

Isovue 300 may cause side effects such as:

  • Chest pain;
  • Slow heartbeat
  • Hot flashes; burning sensation
  • Flushing (warmth, redness, or tingling feeling);
  • Nausea;
  • Hives

There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.

Warnings

If you are infected, Isovue 300 should not be sent to you.

Before you take this drug

Provide any of the following details to your doctor:

  • Any type of reaction to a contrast agent.
  • Liver or kidney disease
  • Heart diseases, including congestive cardiac failure.
  • Stroke, blood clots, or coronary arterial disease.
  • Asthma; hay fever; food allergy
  • Epilepsy
  • Sickle cell anemia
  • Diabetes;
  • An active infection
  • Pheochromocytoma
  • Multiple myeloma; bone cancer
  • A thyroid disorder.

Isovue 300 is not known to harm an unborn child. Inform your doctor if you are pregnant. Inform your doctor if breastfeeding is taking place.

How to take Isovue 300?

Isovue 300 is infused into a vein. This injection will be given by a healthcare provider. While you receive Isovue 300, you may be prescribed medication to help prevent certain side effects.

If you experience any pain or swelling when Isovue 300 is injected, tell your carers.

Drink more fluids both before and after the radiologic test. Dehydration can be caused by isovue 300, and this can have dangerous effects on the kidneys. You should follow your doctor's advice about how much fluid you need to drink before and after the test. You may need to take extra care with older adults in order to prevent dehydration. You may need to have your kidney function checked after receiving Isovue 300.

Some reactions to Isovue 300 have started 30–60 minutes after the first injection. You may be watched by your carers during this time. You want to be sure that you don't have any side effects or delayed reactions. You may experience interference with medical tests up to 16 weeks after taking Isovue 300. Inform any doctor that treats you about the recent use of this medication.

What happens if I miss the dose?

You will not have a schedule of doses since Isovue 300 is only used during radiologic tests.

What happens if I overdose?

Call 1-800-222-1222 for poison help or seek immediate medical attention.

What should be avoided?

You should not become dehydrated in the first few days following Isovue 300. Call your doctor immediately if you experience any nausea or diarrhea. You should follow your doctor's advice on the type and amount of fluids to drink.

Interaction with other drug

Tell your doctor of all medications currently being taken, such as:

  • Diabetes medicine that contains metformin. (Glucophage Glucovance Actoplus Met prandimet Avandamet Janumet Kazano Invokamet Jentadueto Xigduo Synjardy Metaglip and others).

This list is incomplete. Isovue 300 may be affected by other drugs, such as prescription and over-the-counter medicines and vitamin and herb products. This list does not include all possible drug interactions.