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Impoyz cream

Pronunciation: Im-poise

Clobetasol Propionate, 0.025%
Brand Name: Impoyz
Drug class: topical steroids

What is Impoyz Cream?

Impoyz is a topical steroid with a high potency that can be applied topically to reduce inflammation and itch caused by plaque psoriasis, which affects adults over 18 years of age. It contains clobetasol 0.025% and shouldn't be used for longer than two weeks.

Impoyz is a specially formulated cream that uses an ingredient called transcutol to enhance the solubility and permeation of clobetasol into plaques. Impoyz cream is as effective as other clobetasol products but contains half the normal concentration of the drug. This reduces the risk of adverse effects, such as absorption into the bloodstream. Transcutol also has a lower impact on the skin's lamellar layer (a layer made up of lipids, water, and stratum corneum) compared to propylene glycol.Impoyz FDA approval was granted on December 1, 2017.


Impoyz cream contains clobetasol propionate, which can be absorbed through the skin into the bloodstream and cause reversible hypothalamic-pituitary-adrenal (HPA) axis suppression with the potential for glucocorticosteroid insufficiency, including Cushing's,syndrome, hyperglycemia, and glucosuria. Do not use the cream for more than 2 weeks. Do not exceed the recommended dosage. HPA suppression can be monitored periodically.

It is best to avoid using occlusive dressings unless advised by a doctor, as they increase the risk of adverse effects.

Before you take this drug

If you have an allergy to Impoyz, then it is best not to use the product.Tell your doctor about any of the following:

  • Any type of skin infection
  • A skin reaction to steroid medicines;
  • Liver disease
  • An adrenal gland disorder is a condition that affects the adrenal glands.

Topical corticosteroids may increase glucose levels (sugar) in the blood or urine. Inform your doctor if diabetes is present.Impoyz should not be used in children or young adults younger than 18.

Impoyz is not known to harm an unborn child. Inform your doctor if you are pregnant. Use Impoyz only in small amounts and for as little time as possible if you have been instructed to do so.This medicine may make it unsafe to breastfeed. Use Impoyz only in small amounts and for as little time as possible if you have been instructed to do so. Do not apply to the breasts.

Similar/related drugs

Kenalog, Kenalog-40, Dovonex, Cordran Tape, Lexette, Sernivo, and Cloderm

How to take Impoyz cream?

Two times a day, apply a thin layer of Impoyz to the affected area. Rub gently and thoroughly. Follow the instructions exactly.

  • After applying, wash your hands.
  • If your psoriasis has been controlled, stop using Impoyz Cream, but don't use it longer than two weeks. If your psoriasis is not improving after 2 weeks, contact your doctor.
  • Stop using Impoyz if your psoriasis improves sooner than 2 weeks.
  • Do not exceed 50g a week.
  • Use it only if you have thin skin where you plan to apply it.
  • If your doctor has not instructed you otherwise, do not cover, bandage, or wrap the skin area where you applied Impoyz.
  • Use it only on the skin of your arms, legs, and groin.
  • Impoyz should not be used with other corticosteroid medications.

Impoyz is only to be applied to the skin. You should not swallow it, use it near your eyes, or insert the product.

Side effects of Impoyz Cream

Impoyz cream is most commonly associated with skin discoloration.

Topical corticosteroids can cause reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, with the potential for glucocorticosteroid insufficiency.

The following are other side effects that have been reported when using topical corticosteroids:

  • Find out about:
  • Allergic contact dermatitis
  • Burning, itching, swelling, or irritation of the treated skin
  • Dry or cracked skin
  • Redness or crusting on your hair follicles
  • Spider veins
  • Stretch marks and thin skin
  • Rash or hives
  • Temporary hair loss

Your doctor may prescribe an antimicrobial cream if you develop a skin rash while using Impoyz. Your doctor may stop Impoyz if this doesn't work.

You may experience weight gain on your face or shoulders, an increase in body hair, fatigue, mood swings, changes in menstruation, and changes in your sexuality.There may be other side effects. For medical advice on side effects, call your doctor. The FDA can be contacted at 1-800-FDA-1088 to report side effects.

Interaction with other drug

Impoyz, a cream applied to your skin, is unlikely to affect other medications you take. Impoyz should not be used with any other topical or oral steroids, as they could have an additive effect.

Inform your healthcare provider about all medications you take, including prescriptions, over-the-counter medicines, vitamins, and herbal products.