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Imdur

Generic name: Isosorbide mononitrate [ EYE-soe-SOR-bide-MON-oh-NYE-trate ]
Names of brands: Imdur, Monoket, ISMO
Drug class: Antianginal agents

It is believed that the Imdur brand name is removed within the U.S. In the event that generic variants of this drug are accepted by FDA it is possible that there are similar generic versions available.

What is Imdur?

Imdur is an nitrate which dilates (widens) blood vessels and makes more efficient for the circulation of blood, and it is easier for the heart to pump. Imdur is a tablet that has an extended release that is used to stop Angina attack (chest tension). Imdur is not able to treat angina which has already started.

Warnings

You shouldn't use erectile dysfunction medications (Viagra, Cialis, Levitra, Stendra, Staxyn, sildenafil, avanafil tadalafil and Vardenafil) in conjunction with Imdur. Combining these medications could result in a sudden and severe drop of blood pressure. Get medical attention immediately when you notice the first signs of an attack on your heart (chest pressure or pain and pain radiating to your shoulder or jaw sweating, general discomfort feeling). Don't stop using this medication abruptly. A sudden stop could result in angina attacks that are severe.

Isosorbide mononitrate is known to create severe headaches, especially when you first begin using it. The headaches can be less severe over time as you continue using the medication. Don't discontinue taking Imdur. Talk to your doctor prior to taking any painkiller for headaches. Take this medication regularly to avoid angina attacks. Make sure you refill your prescription before you are completely out of medication.

Before you take this drug

You shouldn't use Imdur in the following situations:

  • You are allergic to isosorbide mononitrate isosorbide dinitrate or nitroglycerin.

  • You may be experiencing early warning indications of the possibility of a heart attack (chest pressure or pain and pain that is spreading into your shoulder or jaw nausea, sweating, and vomiting).

It is not recommended to use any erectile dysfunction medication (Viagra, Cialis, Levitra, Stendra, Staxyn, sildenafil and avanafil as well as tadala or Vardenafil) when you are taking Imdur. Combining these medications could result in a sudden and severe drop the blood pressure.

To ensure that Imdur is not harmful to you, inform your doctor whether you suffer from any of the following conditions:

  • Congestive heart failure;

  • Kidney disease kidney disease

  • Lower blood pressure.

It isn't known if Imdur can harm an unborn baby. Consult your physician if you are expecting or planning to be pregnant. It isn't known if isosorbide mononitrate can be found in the milk of a nursing mother or whether it can affect the nursing infant. Consult your physician if you are breastfeeding.

How to take Imdur?

Consume Imdur exactly as directed by your physician. Follow all instructions on the prescription label. The doctor could alter your dosage. Don't take this medication in greater or lesser quantities or for longer periods than the recommended time. If you take too much isosorbide mononitrate it could stop working effectively in managing your condition. It is best to rest or remain at a comfortable place when taking this medication (may cause fainting or dizziness). Do not chew, crush or break the

extended release Imdur tablet

. Take it in whole. There is a possibility that you will have very low blood pressure when you take Imdur. Consult your physician if you have a stomach ache and diarrhoea or are sweating more than normal. Long-term illness could cause an electrolyte imbalance that is serious and make it risky for you to take this drug.

Make sure to take Imdur every day to avoid angina attacks. Make sure you refill your prescription prior to the time you run out of medication completely. It is not advisable to discontinue Imdur abruptly or you may suffer an acute attack of angina. Keep this medicine available throughout the day. Refill your prescription prior to the time you have run out of medicine completely. Keep at room temperature and free of heat, moisture and light. Make sure the bottle is tightly shut when not being used.

What happens if I miss the dose?

Do the missed dose as quickly as you can remember. Avoid your missed dosage if you are nearing the time for the next dose. Don't take any extra medication to make up for the missed dose.

What happens if I overdose?

For medical emergencies, seek emergency treatment or contact for help at the Poison Help line at 1-800-222-1222. A high dose of isosorbide mononitrate may cause death.

The symptoms of an overdose can include an intense throbbing headache as well as confusion, fever, extreme dizziness, rapid or pounding heartbeats. It can also cause vision issues nausea, vomiting, diarrhea that is bloody sweating or clammy skin, fainting, or seizures (convulsions).

What should be avoided?

This medication could impair your reactions or thinking. Be cautious if you drive or engage in any activity which requires you to be alert. Be careful not to get up too fast from a seated or lying place, as you could be shaky. Make sure to get up slowly and steadily yourself to avoid falling.

Do not drink alcohol. Alcohol can increase certain adverse symptoms of Imdur (dizziness and drowsiness, feeling lightheaded, fainting or feeling lightheaded).

Side effects of Imdur

See a doctor immediately in the event that you exhibit symptoms for an allergic reaction, such as symptoms of hives; breathing difficulties and swelling of your lips, face and tongue.

Contact your doctor immediately If you suffer from:

  • A feeling of lightheadedness, as if you're passing out;

  • Worsening angina pain;

  • Heart rate slow or fast; or

  • Heartbeats that beat at a high tempo or beating in your chest.

Imdur may cause severe headaches. The headaches will be less severe over time when you continue using the nitroglycerin. Don't discontinue taking this medication to prevent headaches. Talk to your doctor prior to taking any medication for headaches.

The most common Imdur-related side effect could include:

  • Headaches, or

  • Flushing (warmth of redness or tingling sensation).

This is not a comprehensive list of all side effects. others could happen. Contact your physician for advice regarding medical adverse effects. You can report adverse reactions to the FDA at 1-800-FDA-1088.

Details on dosage

Usual Adult Dose for Angina Pectoris Prophylaxis:

EXTENDED RELEASE:

30-60 mg taken daily, orally in the early morning

Maximum dosage: 240 mg taken orally at least once per day in the morning

Comments:

Swallow whole (do not chew or crush) with a half-glass of water.

Start at the low portion of the dosing range for patients who are elderly.

Use: To prevent angina pectoris caused by coronary artery disease; the onset of action is not quick to be effective in stopping an acute anginal event.

Usual Adult Dose for Angina Pectoris:

EXTENDED RELEASE:

30-60 mg taken orally every day, in the early morning

Maximum dosage: 240 mg taken orally at least once per day in the morning

Comments:

Suck whole (do not chew or crush) with half-glass of water.

Start at the lower portion of the dosing range for older patients.

Use: To prevent angina pectoris caused by coronary artery disease; the onset of the action isn't sufficiently quick to be effective in stopping an acute anginal event.

Interaction with other drug 

Combining Imdur with other medications can result in severe lower blood pressure. This includes medications to treat erectile dysfunction and the condition known as pulmonary arterial hypertension. A life-threatening and serious adverse reaction could be experienced.

Inform your doctor about all your medications currently in use and all you are about to start or stop using, in particular:

  • Avanafil (Stendra);

  • Riuretic or "water pill";

  • Nitroglycerin;

  • Riociguat (Adempas);

  • Sildenafil (Viagra, Revatio);

  • Tadalafil (Cialis, Adcirca); or

  • Vardenafil (Levitra, Staxyn).

This list isn't complete. Other medications may be incompatible with isosorbide mononitrate which includes prescription and over-the-counter medications as well as vitamins and herbal products. There are not all interactions included in this guide to medication.

 

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Prescription only

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