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What is Idecabtagene vicleucel?
Idecabtagene vicleucel is an immunotherapy medicine that treats multiple myeloma in adults. Idecabtagene vicleucel should only be used after four other treatments have failed.idecabtagene vicleucel can be made from white blood cells that have been removed from the blood.
Idecabtagene vicleucel can be obtained under a special programme. You must register for the programme, and you must understand the risks and advantages of the medicine.idecabtagene vicleucel can be used in other ways not mentioned in this guide.
Side effects of Idecabtagene vicleucel
Seek immediate medical care if you have any of these symptoms: difficulty breathing, swelling in your face, lips, throat, or tongue.
Cytokine release syndrome (crs) is a serious side effect associated with idecabtagene. If you experience any of the following symptoms, tell your carer immediately: fever; chills; difficulty breathing; severe nausea; and diarrhea. Your carers have medications available to treat crs quickly if it occurs.
Also, notify your carers if you experience any of the following signs: difficulty speaking, memory or thinking problems, confusion, or seizures.
Call your doctor immediately if you:
- Headaches, dizziness, and drowsiness;
- Problems with memory or thinking;
- You may have difficulty understanding or speaking.
- Sleep disorders;
- Seizure;
- Right-sided upper abdominal pain, vomiting, loss of appetite, yellowing of the skin or eyes, and feeling unwell
- Low blood cell counts can cause fever, chills, and fatigue, as well as flu-like symptoms. Other symptoms include mouth sores or skin sores. They may also be accompanied by easy bruising and unusual bleeding.
Side effects that may occur from idecabtagene vicleucel include:
- Cytokine-release syndrome
- Headache, dizziness;
- Speech problems;
- Low blood cell count
- If you have any of the following symptoms, it is likely that you are infected with:
- Symptoms of nausea or diarrhea include:
- Pain in your joints or muscles
- You may experience swelling in any part of your body.
- Cold symptoms, including a stuffy nose and sneezing. Sore neck. Cough.
There may be other side effects. For medical advice on side effects, call your doctor. The fda can be contacted at 1-800-fda-1088 to report side effects.
Warnings
The cytokine-release syndrome is a serious side effect that can cause fever, chills, and difficulty breathing. If this occurs, your carers have medications to treat it quickly.
Idecabtagene vicleucel may also cause nerve problems that are life-threatening. If you experience difficulties with speech, thinking, memory, or confusion, seek immediate medical attention.
Before you take this drug
Tell your doctor about any of the following:
- An active infection or inflammation
- Hepatitis b
- Cytomegalovirus;
- If you received a vaccination in the last 6 weeks,
Before receiving this medication, women may be required to undergo pregnancy testing. You may need to use contraception during treatment and for a short time after to prevent pregnancy.
After your baby is born, it may be necessary to test the blood of your baby if you received idecabtagene vicleucel while pregnant. The blood test is done to determine if the medicine has had any effect on the baby.breastfeeding may not be possible while taking this medication. You should consult your doctor if you are concerned about any risks.
How to take Idecabtagene vicleucel?
Idecabtagene vicleucel can only be obtained at a hospital or clinic that is authorized and administered by specially-trained healthcare professionals.idecabtagene vicleucel is given after a procedure called leukapheresis (loo-kuh-fuh-ree-sis).leukapheresis is the process of collecting some of your own blood through a catheter that's placed in a vein. The catheter is attached to a machine that separates the white blood cells and other blood components. The cells will then be sent to a lab, where they will be made into idecabtagene vicleucel. This process takes four weeks.
You will receive chemotherapy about 3 days prior to receiving idecabtagene vicleucel. This helps prepare your body.before you are given idecabtagene vicleucel, you will receive other medications that help to prevent side effects and allergic reactions.your care provider will inject the medicine through an iv into your vein once your body is ready.
After receiving idecabtagene vicleucel, you will be closely monitored for at least seven days to ensure you don't have any serious side effects or allergic reactions.to be sure that idecabtagene vicleucel is not causing any harmful effects, you will need to have frequent blood tests.you may be at greater risk of developing cancer if you use idecabtagene. You should discuss this with your doctor. You may require cancer screening tests for the rest of your life.
Idecabtagene vicleucel can cause false positive results in a lab test for hiv (human immunodeficiency). Inform any doctor that treats you about your use of idecabtagene.plan to stay close to the hospital or clinic that you visited where you received your idecabtagene, vicleucel, for at least four weeks. You should not be so far from the hospital that it will take you more than two hours to get back.
What happens if i miss the dose?
If you miss any chemotherapy treatments or medication to prevent side effects from idecabtagene vicleucel, call your doctor.
What happens if i overdose?
In a medical setting, an overdose is treated immediately.
What should be avoided?
Idiocabtagene vicleucel may cause drowsiness or confusion, memory problems, coordination issues, or seizures. Do not drive or operate machinery for 8 weeks following treatment with idecabtagene vicleucel.
Consult your doctor prior to receiving a "live vaccine". Live vaccines are available for measles (chickenpox), rubella (mmr), yellow fever, rotavirus (typhoid), varicella, typhoid (rotavirus), varicella, zoster, and influenza (nasal flu).don't donate any organs, tissues, or cells.
Interaction with other drug
Other drugs, such as vitamins and herbal remedies, may also affect idecabtagene. Inform your doctor of all the medicines you are currently taking and those that you have started or stopped using.