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Name of the Generic: Hydrocortisone (oral) (oral) HYE-droe, KOR-ti-sone [HYE-droeKOR-tisone]
The Brand Names are Alkindi Sprinkle and Cortef.
Dosage Formats: Oral granule (0.5 mg; 1 mg; 2 mg; 5 mg); oral tablet (10 mg; 20 mg; 5 mg);
Drug Class: Glucocorticoids

What Is Hydrocortisone?

Hydrocortisone is a steroid medication that is used to treat various diseases, including allergies, skin conditions, arthritis, ulcerative colitis, lung disorders, lupus, and certain blood cell disorders like anemia (low red blood cells) or thrombocytopenia (low platelets).

Hydrocortisone may also be utilized to replace steroids for people suffering from adrenal deficiency (decreased levels of the natural steroids produced in the adrenal glands).Hydrocortisone is also used to treat certain cancers like leukemia, lymphoma, and multiple myeloma.Al Kindi Sprinkle is accepted for use by people from birth until 17 years old.Hydrocortisone is also used for reasons not mentioned in this medication guide.

Side effects Of Hydrocortisone

See a doctor immediately. If you are experiencing symptoms that are warning signs of an allergic response, like hives, trouble breathing, and swelling of your lips, face, or tongue,

Hydrocortisone could cause severe adverse effects. Consult your physician immediately in the event of:

  • Blurred vision blurred vision, eye pain, or redness blurred vision, halos of light around the eyes;
  • Muscle weakness or diminution of mass
  • Uncharacteristic or new pain in your joints, bones, or muscles;
  • Severe headaches, ringing in your ears, and pain behind your eyes;
  • Strange behavior or mood changes;
  • A seizure;
  • Liquid retention: breathlessness (even when lying down) or swelling; rapid weight growth (especially on your face and your midsection);
  • New signs of symptoms, such as fever, chills, cough, breathing problems, sores in your mouth and on your body, diarrhea, or burning sensations when you pee;
  • Increased adrenal gland hormones—slow healing of wounds, discoloration of the skin, thinning of body hair, fatigue, changes in the menstrual cycle, or sexual activity;
  • Reduced adrenal gland hormones, causing weakness and fatigue, as well as diarrhea, nausea, menstrual irregularities, skin discoloration, craving salty food items, and feeling lightheaded.

Hydrocortisone can affect growth in children. Inform your doctor that your child isn't growing as normal with hydrocortisone.

Common side effects of hydrocortisone include:

  • The skin is becoming thinner, bruises, or discoloration
  • More transpiration;
  • Stomach bloating;
  • Menstrual changes;
  • An increase in appetite and weight gain
  • Headache, dizziness,
  • Trouble sleeping.

This is not a comprehensive list of all the side effects. Others could happen. Consult your physician for advice regarding medical adverse effects. You can report symptoms to the FDA at 1-800-FDA-1088.


Discuss with your doctor any illness or infection that you have experienced in the last couple of weeks.

Before you Take this Drug

Hydrocortisone should not be used in the event that you are allergic to hydrocortisone or corticosteroids or suffer from a systemic fungus disease.

Steroids may weaken an immune system, which makes it easier to contract an infection or worsen an infection that you already suffer from. Inform your doctor of any illness or infection that you have suffered from in the last few weeks.

Speak to your doctor if you have ever suffered from:

  • The heart condition, high blood pressure;
  • Tuberculosis;
  • Kidney disease;
  • Cirrhosis or any other liver disease;
  • A thyroid disorder
  • Low densities of bone (osteoporosis);
  • Stomach ulcers stomach ulcers, ulcerative colitis, and diverticulitis;
  • Diabetes;
  • A colostomy or ileostomy;
  • Depression and mental health
  • Glaucoma or cataracts
  • Eye herpes infection in the eyes;
  • An illness of the muscles, like myasthenia gravis.

Long-term use of steroids could cause the loss of bone (osteoporosis), particularly when you smoke or don't exercise, if you do not consume enough calcium or vitamin D within your daily diet, or if you have an ancestral background of osteoporosis.

It isn't known if this medication will cause harm to the unborn baby. However, taking this medicine during pregnancy can cause hormonal imbalances in the baby. Consult your physician if you are expecting or planning to become pregnant.Consult your doctor to determine whether it is safe to breastfeed while taking this medicine.

How to take Hydrocortisone?

Follow the instructions on the prescription label and go through all medication guides or instruction sheets. The doctor might alter your dosage. Follow the medication precisely as prescribed.Consume it with food if hydrocortisone is causing stomach upset.

Do not ingest the Alkindi Sprinkle capsule in its entirety. Unscrew the capsule and put the medicine granules over the tongue prior to taking them in. You can also mix the granules in soft foods like applesauce or yogurt (not in liquid). Drink the mixture immediately without chewing.

Drink plenty of water immediately after you have taken the Alkindi Sprinkle Granule Mixture. If you give these medicines to a child, you can give baby formula and breastmilk.If you're having difficulty sleeping, you might need to take this medicine earlier in the morning. Be sure to follow the dosage guidelines set by your doctor with diligence.

The dose you take can change when you are suffering from a serious illness, an infection or fever, surgery, or an emergency medical situation. Discuss with your doctor any of these conditions that may affect you.Your doctor will examine your health regularly.Do not stop taking hydrocortisone abruptly. Follow the advice of your doctor regarding increasing your dosage.Maintain at room temperature, far from heat, humidity, and light.Wear an alert label or carry an ID that lets people know that you are taking steroids.

What Happens If I Miss a Dose?

Do not take the medicine for as long as you can. However, avoid any missed doses if you are nearing the time to take the next dose. Don't take two doses at once.

What Happens If I Overdose?

Get medical attention in an emergency or contact the Poison Help line toll-free at 1-800-222-1222.

Long-term use or high doses of steroid medication could cause thinning of the skin, easily bruising, changes in the body's fat (especially on your neck, face, back, waist, and face), increased facial hair or acne, menstrual issues, impotence, or a loss of desire to have sexual activity.

What Should be Avoided?

Do not receive the "live" vaccine. The vaccine may not function in the same way if you are taking hydrocortisone. Live vaccines comprise measles, mumps, measles, and rubella (MMR), as well as typhoid, rotavirus fever, varicella (chickenpox), and zoster (shingles).

Beware of those with illnesses or suffering from illnesses. Contact your doctor for treatment to prevent infection in the event that you have been exposed to measles or chickenpox. These illnesses can be very serious or even fatal for people who take hydrocortisone.

Interaction with Other Drugs

It is sometimes not safe to take certain medicines together. Certain drugs may affect your blood levels and the other drugs you are taking, which could cause more side effects or make the medication less effective.

Inform your doctor about the medicines you are currently taking. A variety of drugs can alter hydrocortisone, including:

  • Birth control pill and hormone therapy
  • Heart medicine;
  • Insulin or oral diabetes medicine;
  • Medicines to treat an infection
  • Seizure medication;
  • A blood thinner like warfarin (Coumadin and Jantoven)
  • These are NSAIDs (nonsteroidal anti-inflammatory drugs): aspirin, ibuprofen, aspirin (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac (also known as indomethacin), diclofe, and a few others.

This is not a complete list, and a variety of other medications could alter the effects of hydrocortisone. This includes over-the-counter and prescription medications, vitamins, and herbal supplements. The list of potential drug interactions is not comprehensive. are listed here.



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