What is Hydrochlorothiazide and lisinopril ?
Hydrochlorothiazide works as a diuretic. Lisinopril belongs to the ACE-inhibitor family (ACE is an angiotensin-converting enzyme).A combination medicine of hydrochlorothiazide and lisinopril can be used to treat hypertension. You may reduce your risk of stroke and heart attacks by lowering your blood pressure.This medication guide does not list all possible uses of hydrochlorothiazide or lisinopril.
Side effects of Hydrochlorothiazide and lisinopril
If you experience any of the following symptoms of an allergic reaction, seek immediate medical attention: hives, severe stomach pain, difficulty breathing, swelling of your lips, face, tongue, or throat. If you're African-American, your chances of having an allergic reaction are higher.
Lisinopril and hydrochlorothiazide can cause serious side effects. If you experience:
- A feeling of lightheadedness, as if you could pass out.
- Eye pain and vision problems
- Little or no urination
- Feeling weak or drowsy
- Sore throat; fever; mouth sores;
- Jaundice
- High potassium: nausea; chest pain; irregular heartbeats; and loss of mobility.
- Low sodium—leg pain, constipation, increased thirst, urination or numbness, or muscle weakness.
- Low sodium: headache; confusion; slurred words; severe weakness; nausea; loss of coordination.
Some of the common side effects associated with hydrochlorothiazide or lisinopril include:
- Cough;
- Headache;
- Dizziness;
- Tired feeling
There may be other side effects.For medical advice regarding side effects, call your physician. The FDA can be reached at 1-800-FDA-1088 in order to report them.
Warnings
Use it only if you're not pregnant. Stop taking lisinopril or hydrochlorothiazide if you are pregnant. Tell your doctor immediately.This medicine should not be used if the patient has ever suffered from angioedema. It is also not recommended if the patient has an allergy to sulfa drugs. Do not take hydrochlorothiazide or lisinopril if you have ever had angioedema, if you are unable to urinate, or sulfa drugs (such as Entresto) within 36 hours of taking the medicine.You should not take lisinopril and hydrochlorothiazide together if you have diabetes.
Before you take this drug
This medicine should not be used if you have an allergy to hydrochlorothiazide, lisinopril, or:
- You have angioedema.
- You are unable to urinate.
- You recently took a medicine for your heart called sacubitril.
- Are You Allergic to Sulfa Drugs
- If you've ever experienced a severe reaction to an ACE inhibitor, such as benazepril (captopril), enalapril (enalapril), fosinopril (moexipril), perindopril, or quinapril,
Take lisinopril and hydrochlorothiazide at least 36 hours after taking a medicine containing sacubitril, such as Entersto.Do not take lisinopril and hydrochlorothiazide together with any blood pressure medication containing aliskiren if you have diabetes.If you have kidney problems, you may need to avoid using aliskiren with hydrochlorothiazide or lisinopril.
Inform your physician of any of the following issues:
- Kidney disease (or dialysis if you have it);
- Liver disease, or cirrhosis.
- Glaucoma;
- Congestive cardiac failure, or heart disease.
- Allergies or asthma
- Gout;
- Lupus;
- An allergy to penicillin or sulfa drugs;
- If you're on a diet low in salt,
If you are pregnant, do not take this medicine. If you are pregnant, stop using the medication and immediately tell your doctor. Lisinopril may cause harm or even death to an unborn child if taken during the second or third trimester.If you are taking hydrochlorothiazide or lisinopril, it is not recommended that you breastfeed.Anyone younger than 18 is not allowed to use lisinopril or hydrochlorothiazide.
How to take Hydrochlorothiazide and lisinopril?
Read all the instructions or guides that come with your medication and follow the directions. Sometimes, your doctor will change the dose. You must take the medication exactly as prescribed.If you experience persistent vomiting, diarrhea, or if your sweating is higher than normal, call your doctor. It is easy to become dehydrated when taking lisinopril and hydrochlorothiazide. This can cause very low blood pressure or electrolyte disorders, as well as renal failure.You may also need blood tests every now and then.Tell your doctor if you are currently taking this medication and if you require surgery.Even if you are feeling well, continue to take this medication as prescribed. High blood pressure can often be symptomless. Blood pressure medications may be needed for the rest of your life.Store away from moisture, heat, and light at room temperature.
Details on dosage
Usual Adult Dose for Hypertension:
Initial dose: Lisinopril (10–20 mg) orally, once daily, depending on the current monotherapy dosage.
Maximum dose: hydrochlorothiazide 50 mg-Lisinopril 80 mg per day
Comments:
Increase the dose every 2–3 weeks.
If blood pressure is controlled by hydrochlorothiazide monotherapy (25 mg per dose) but potassium loss is significant, similar or better blood pressure control can be achieved without electrolyte disruption with hydrochlorothiazide (12.25 mg) and lisinopril (10 mg) taken orally, once daily.
What happens if I miss the dose?
If you are almost due for your next dose, skip the missed one. Never take two doses of the same medicine at once.
What happens if I overdose?
Reach out for help or seek medical attention immediately when dealing with poison. Call 1-800-222-1222.
What should be avoided?
The use of hydrochlorothiazide can increase your risk of skin cancer. Avoid tanning beds or sunlight. When you're outdoors, wear protective clothing and use sunblock with an SPF of 30 or more. You may be asked to undergo regular skin checks by your doctor.Alcohol can lower blood pressure further and increase the side effects of hydrochlorothiazide or lisinopril.If you are taking this medication, do not take potassium supplements or sodium substitutes unless you have been told to by your doctor.You could feel dizzy if you quickly rise from sitting or lying positions.Drink enough fluids to avoid becoming dehydrated or overheated during exercise or in hot weather. You should follow your doctor's advice on the amount and type of fluids to drink. Drinking too much liquid is as dangerous as not drinking enough.
Interaction with other drug
Tell your doctor about your other medications, including:
- Any other blood pressure medication
- Lithium;
- Everolimus, sirolimus, temsirolimus,
- Aspirin, Ibuprofen, Naproxen, Diclofenac, and Indomethacin are all nsaids.
This list is incomplete. Hydrochlorothiazide may interact with lisinopril and other drugs, including vitamins and herbs. This list does not include all possible drug interactions.
