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Fosamprenavir

Generic names: fosamprenavir ([FOSamPRENa-veer])
Brand name: Lexiva
Dosage forms: Oral suspension (50 mg/mL), oral tablet (700 mg).
Drug class: protease inhibitors

What is Fosamprenavir?

Fosamprenavir, an antiviral medication, prevents the human immunodeficiency virus (HIV) from multiplying within your body. Fosamprenavir treats HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Fosamprenavir can be used by adults and children over the age of 4 weeks. Fosamprenavir does not cure HIV or AIDS. Fosamprenavir can be used in other ways not mentioned in this guide.

Side effects of Fosamprenavir

If you experience symptoms of an allergic response (hives or difficulty breathing, swelling on your face or in your throat) or a severe reaction to the skin (fever or sore neck, burning or itching eyes, skin pain or blisters, or a red or purple rash with blisters and peeling), seek emergency medical attention.

If you experience:

  • If you notice a pale or yellowed complexion, dark urine, confusion, or weakness, then it is important to consult your doctor.
  • Increased urination or extreme thirst
  • Low blood sugar: increased thirst, frequent urination and fruity breath odor;
  • Kidney Stones Symptoms: Sudden pain and burning in the lower back or sides; blood in urine.

Fosamprenavir can affect your immune system and cause side effects. This may occur even weeks or months after taking this medication. You should tell your doctor if:

  • Signs of infection: fever, night sweats, swollen lymph glands, colds, sores, coughing, wheezing and diarrhea.
  • Problems with balance, eye movements, or speech, or even a prickly sensation;
  • Impotence, menstrual irregularities, and swelling of the neck or throat

Fosamprenavir can cause a variety of side effects.

  • Fever or other symptoms of infection
  • Nausea, vomiting, diarrhea;
  • Rash;
  • Headache;
  • Changes to your arms, legs and breasts as well as any alteration to body fat levels could indicate that there have been changes to your shape or location - as well as potential increases or decreases.

Other possible side effects could also occur. To get medical advice for side effects, contact your physician; otherwise the FDA can be reached at 1-800-FDA-1088 and reported adverse events directly.

Warnings

Inform your physician of any medications you are currently taking as well as any new ones.Some drugs are not to be taken together, and others can cause drug interactions.

Before you take this drug

If you have an allergy to fosamprenavir, it is best not to use this drug.

Certain medicines may cause harmful or unwanted effects when combined with fosamprenavir. If you are also taking:

  • Alfuzosin;
  • Delavirdine;
  • Rifampin;
  • John's wort;
  • When sildenafil is used to treat pulmonary arterial hypertension (pah), it's called revatio.
  • Antipsychotic medicine—lurasidone, pimozide;
  • Cholesterol-lowering medicine—lovastatin, simvastatin;
  • Ergot medicine: dihydroergotamine, ergotamine, ergonovine, and methylergonovine;
  • Heart rhythm medicine—flecainide, propafenone;
  • A sedative is oral midazolam or triazolam.

Tell your doctor about any of the following:

  • Liver disease includes hepatitis a and c;
  • Kidney disease
  • A bleeding disorder, such as hemophilia.
  • Diabetes;
  • Sulfa drugs can cause an allergic reaction.

Use your medication properly to control infections. HIV can be transmitted to your child if you do not control the virus during pregnancy. You may have your name listed in a registry that tracks the effects of antiviral medicines on a baby. Fosamprenavir may make birth-control pills ineffective. You may experience abnormal liver function tests if you take fosamprenavir with ritonavir and use birth-control pills. Ask your doctor if you can use non-hormonal birth control to prevent pregnancy (condoms, diaphragms with spermicide). Breast-feeding is not recommended for women with HIV/AIDS. Even if the baby is not born with HIV, it can be transmitted to the child through your breast milk. Fosamprenavir shouldn't be given to a baby younger than four weeks (28 days).

How to take Fosamprenavir?

Read all instructions or guides that come with your medication and follow all directions. Follow the directions on the label. Fosamprenavir can be taken either with or without food. Fosamprenavir should be taken either with or without food by adults and children. Before measuring a dose, shake the orally suspended liquid. Use the provided dosing device or a dose-measuring tool (not a spoon). Fosamprenavir dosage is based on child weight. The dose your child needs can change if they gain or lose weight. Medical tests will be required frequently. Read all the instructions and medication guides that you receive. Do not alter your dosage or schedule without consulting your doctor. Each person living with HIV should be under the care and supervision of a physician. Keep the fosamprenavir tablet away from moisture, heat, and other sources of heat. Store fosamprenavir liquid in a refrigerator, but don't let it freeze.

What happens if I miss the dose?

If you are almost due for your next dose, skip the missed one. Never take two doses of the same medicine at once. Refill your prescription before you run out.

What happens if I overdose?

Call 1-800-222-1222 for poison help or seek immediate medical attention.

What should be avoided?

Fosamprenavir does not stop the spread of your illness. Share razors and toothbrushes. Do not engage in unprotected sexual activity. Speak to your doctor about the best ways to prevent HIV from being transmitted during sex. Even healthy people should never share syringes for drugs or medicines.

Interaction with other drug

It is sometimes not safe to take certain medications together. Some drugs may affect the blood levels of drugs that you are taking, which can increase side effects and make them less effective. Fosamprenavir can interact with many drugs, and certain drugs shouldn't be taken together. Inform your doctor of all the medicines you are taking and those that you have started or stopped using. Included are prescription and non-prescription medicines, vitamins, and herbal products. This list does not include all possible interactions.

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