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Generic name:Ertugliflozin [Er-toogli-FLOE Zin]

Brand name: Steglatro
Oral tablet: 15 mg or 5 mg
Drug class: SGLT-2 inhibitors

What is Ertugliflozin?

Ertugliflozin can be used in conjunction with exercise and diet to help control blood sugar levels among adults who have type 2 diabetes mellitus. Ertugliflozin does not treat type 1 diabetes.This medication guide does not list all possible uses of ertugliflozin.

Side effects of Ertugliflozin

If you experience any of the following symptoms of an allergy: difficulty breathing, hives, swelling in your lips, face, throat, or tongueIf any of these symptoms arise, seek medical help immediately. The symptoms can get worse very quickly.

Ertugliflozin may cause serious side effects. If you experience:

  • New pain or tenderness in the legs or feet, as well as sores or ulcers;
  • Little or no urine;
  • Ketoacidosis is characterized by nausea and vomiting. Other symptoms include stomach pains, confusion, unusual sleepiness, or difficulty breathing.
  • Low sugar—headache; sweating; confusion, irritability, or dizziness. Rapid heartbeat.
  • Dehydration symptoms: lightheadedness, dizziness, and weakness
    Signs of a urinary tract infection include: pain or burning while urinating, an increase in urination and blood in the urine.

Some side effects are more common in elderly adults.

Some of the common side effects associated with ertugliflozin include:

  • Vaginal odor, discharge, or itching;
  • Redness, itching or swelling around the penis, or rash
  • Urinating more often than normal

There may be other side effects. For medical advice on side effects, call your doctor.Report any adverse reactions by calling the FDA at 1-800-FDA-1088.

Similar/related drugs

Ozempic, Mounjaro, Metformin, Trulicity, Lantus, Victoza, and Tresiba


Ertugliflozin can increase the risk of lower-leg amputation. This is especially true if you've had an amputation in the past, have a foot wound, have heart disease, or have circulation issues.Ertugliflozin may cause severe infections of the vagina or penis. Seek medical attention immediately if there is burning, itching, or discharge in your genital area or rectal region, or if you experience pain, swelling, or redness.

Before you take this drug

If you're allergic or have any of the following:

  • If you have severe kidney disease or are currently on dialysis, this is a serious condition.

Ertugliflozin can increase the risk of lower-leg amputation. This is especially true if you've had an amputation in the past, have a foot wound, suffer from heart disease, circulatory problems, or are suffering from nerve damage.

If you've ever:

  • Heart problems
  • A diabetic ulcer, or an amputation.
  • You may have problems with your feet or legs, such as nerve or circulation issues.
  • Liver or kidney disease
  • Other urination issues or bladder infections
  • Low blood pressure
  • Diabetic ketoacidosis;
  • Surgery for pancreas problems
  • If you are a frequent alcohol drinker,
  • If you are planning surgery,
  • If you are suffering from type 1 diabetes,
  • If you're on a diet low in salt,

If you're pregnant, follow your doctor’s advice about how to use ertugliflozin. Controlling blood sugar is important during pregnancy. Your dose may change from one trimester to the next.Ertugliflozin should not be used during the second and third trimesters of pregnancy.Breastfeeding is not recommended while taking ertugliflozin.

How to take Ertugliflozin?

Read all the instructions or guides that come with your medication and follow the directions. Sometimes, your doctor will change the dose. You must take the medication exactly as prescribed.Take ertugliflozin either with food or without.If you have a fever, nausea, or diarrhea or are drinking less fluid or eating less than normal, call your doctor.You will have to check your blood sugar often, and you may need to measure the amount of ketones in your urine. Ertugliflozin may cause dangerous ketoacidosis. If your urine tests show ketones, even if your blood sugar level is normal, contact your doctor.Everyone with diabetes can experience low blood sugar. The symptoms of low blood sugar include headaches, sweating, and irritability. juices, crackers, or raisins on hand to treat low blood sugar.

If you are suffering from severe hypoglycemia, your doctor may prescribe an emergency injection kit. Make sure that your close family members and friends are familiar with how to administer this emergency injection.Watch for other signs such as blurred vision or increased thirst, fatigue, headaches, and hyperglycemia.Stress, illness, surgeries, alcohol, and skipping meals can all affect blood sugar levels. Consult your doctor if you are changing the dosage or schedule of your medication.Tell your doctor that you are using ertugliflozin. Inform any physician who treats you about your use of ertugliflozin.Ertugliflozin may be part of an overall treatment plan that includes diet, physical activity, weight management, regular blood glucose testing, and other medical attention. You should follow your doctor’s advice.Keep away from heat and moisture. Store the unused tablet in the original foil blister package.

Details on dosage

Adult dosage for diabetes type 2:

Initial dose: Orally, 5 mg once daily in the morning
Patients who tolerate the treatment and need additional control of their blood sugar levels may be increased to 15 mg orally, once daily.
Maximum dose: 15 mg per day.
Before starting therapy, it is important to correct the volume depletion.
This drug should not be used by patients who have diabetes type I, as it can increase their risk of developing diabetic ketoacidosis.
It is used as an adjunct to diet, exercise, and weight loss in adult patients with type 2 diabetes.

What happens if I miss the dose?

If you are almost due for the next dose, skip the missed one. Never take more than one dose at a time.

What happens if I overdose?

Call 1-800-222-1222 for poison help or seek immediate medical attention.

Avoid this

You may get dizzy if you stand up quickly from a seated or lying position.

Interaction with other drug

Your doctor might need to adjust your dose of other diabetes medications you take regularly when you stop or start taking ertugliflozin.Other medications, such as prescription drugs, over-the-counter products, vitamins, and herbal remedies, may also affect Ertugliflozin. Inform your doctor of all the medicines you are taking and those that you stop or start using.



Prescription only

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