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Generic Name: Ethinyl Estradiol and Desogestrel [EH-thih-nill-ess-tra-DYE-ole and Dess-oh-JESS-trel]

Brand Names: Apri, Azurette, Caziant, Cyred EQ… Show All 18

Drug class: contraceptives

What is Enskyce?

Enskyce is a birth control medication that contains women's hormones that block the ovulation process (the release of eggs from the ovary). Enskyce is also a cause of changes in the cervical mucus as well as the lining of your uterus. This makes it difficult for sperm to enter the uterus and for fertilized eggs to get attached to the uterus.Enskyce is a medication used to stop pregnancy. There are a variety of kinds of this medication on the market. Some brands are not included in this leaflet.Enskyce can also be used to treat conditions not covered in this guideline.

Side effects of Enskyce

Contact a medical professional immediately. Get medical attention immediately if you notice symptoms or warning signs of an allergic response, like hives, trouble breathing, and swelling of your lips, face, and tongue.Birth control pills could result in serious adverse effects. Do not use birth control pills, and contact your doctor immediately if you suffer from:

  • Indications of symptoms of a stroke, sudden weakness or numbness. Serious headache and slurred speech. Difficulties with balance or vision;
  • Symptoms for a blood clot inside the lung: chest pain, an abrupt and loud cough or shortness of breath, nausea, and vomiting up blood;
  • Indications for a blood clot within the body, such as pain, swelling, warmth, or pain within one leg.
  • Heart attack symptoms include chest pressure or pain that spreads to your shoulder or jaw, nausea, and sweating.
  • Liver problems: swelling in the midriff, left-sided stomach pain, a loss of appetite dark urine, black stool, jaundice (yellowing of the eyes or skin);
  • Increased blood pressure, severe headache, blurred vision, and pounding in your neck or ear
    depression: mood changes, feelings of self-worth devaluation, a loss of enthusiasm for things you previously loved, and new sleep issues thoughts about self-harm;
  • Swelling in your ankles, hands, or feet; lumps in your breasts;
  • Shifts in the pattern or intensity of migraine headaches.

Common negative effects of the Enskyce drug could include:

  • Weight increase, weight gain, nausea, vomiting, or breast tenderness or bleeding from the breast;
  • Acne, darkening of the facial skin,
  • Contact lens problems.

This is not a comprehensive list of possible side effects, and other side effects could occur. Contact your doctor to seek medical advice on adverse effects.Report any adverse side effects directly to the FDA at 1-800-FDA-1088.


Do not use birth control pills when you are expecting or have just had a baby.It is not recommended to take birth control medications if you are suffering from heart issues, vaginal bleeding, liver issues, or severe migraine headaches in the event that you are also taking a certain hepatitis C medication, if you're scheduled to undergo major surgery, if you smoke and are over 35, or if you have suffered a heart attack, stroke, blood clot, or jaundice brought on by birth control pills, as well as cancer of the breast, the uterus/cervix, or vagina.

Prior to using this drug

The use of contraceptive pills may increase the risk of stroke, blood clots, and heart attack. There is a higher risk if you suffer from elevated blood pressure, diabetes, high cholesterol, or obesity. Your risk of suffering from stroke or blood clots is highest in the first year of using birth control medications. The risk increases when you begin taking birth control pills after not taking them for four weeks or more.Smoking could increase the risk of blood clots developing, strokes, or heart attacks triggered by birth control medications, particularly for those over 35.Use it with caution if you're expecting. Stop using Enskyce and notify your doctor when you are pregnant or do not have two menstrual periods in one go. If you've recently had an infant and are waiting at least 4 weeks before you start taking birth hormone pills to prevent pregnancy,

It is not recommended to take pills to control your birth if you are:

  • Untreated or uncontrolled high blood pressure as well as the presence of heart diseases (chest tension, coronary artery disease, a history of heart attack or stroke, circulation issues, or bleeding clots) or a greater chance of developing blood clots as a result of an issue with the heart or hereditary blood disorder
  • A history of cancer related to hormones as well as cancers of the breast, vagina, uterus, cervix, or vagina;
  • Vaginal bleeding unusual that hasn't been inspected by an ophthalmologist;
  • Liver disease or liver cancer, if you take any hepatitis C medication containing ombitasvir, paritaprevir, or ritonavir with or without dasabuvir, or if you have a history of jaundice caused by pregnancy or birth control pills;
  • Extreme migraine headaches (with an aura, numbness, visual changes, or weakness) Particularly when you are over 35 years old or smoke cigarettes and are older than 35.

Speak to your physician immediately if you have ever suffered from:

  • Heart disease, high blood pressure, varicose veins, or if you're at risk of blood clots, cholesterol levels too high or triglycerides, or are overweight.
  • Depression, migraine headaches, diabetes gallbladder problems;
  • Kidney or liver disease
  • Menstrual cycle irregularities, fibrocystic breast disease lumps, nodules, or a mammogram that is abnormal.

Consult your doctor to determine whether it is safe to breastfeed while taking this medication.

How do I take Enskyce?

Follow all instructions on the label of your prescription and read the medication guide or instructions sheets. Follow the medication precisely as directed.It is recommended to take your initial pill the day you begin your menstrual cycle or the day after your period starts. It is possible to require backup birth control, like condoms or fertilizer, before you begin using this medication. Follow the instructions of your physician.You should take one pill a day and no more than 24 hours in between. When the pills have run out, start a fresh pack the next day. You could become pregnant if you don't take one pill a day. Refill your prescription prior to the time you are completely out of pills.Certain birth control kits contain seven "reminder" pills to keep your cycle on track. The period usually begins after you take these pills for reminders.It is possible that you have bleeding that is a breakthrough. Inform your doctor if the bleeding persists or becomes very heavy.Utilize a backup birth control plan if you're sick and suffering from severe vomiting or diarrhea.Any surgeon or doctor who sees you must be aware that you're taking contraceptives for birth.When you are taking birth medication to prevent birth, you'll be required to see your physician often.Place it in a cool, dry place free of heat and moisture.

What happens if I miss the dose?

Follow the instructions on your prescription label, and go through all medication guides or instructions. The absence of medication increases your chance of becoming pregnant.If you do not take one active pill, you should take two pills the next day you can remember. Then, take one pill a day throughout the pack.If you do not take two active tablets in one row in the first or second week, then take two pills daily for two days. Then, take one pill a day throughout the group. You should use backup birth control for a minimum of 7 days after the missing pills.If you do not take two active pills within Week 3, you can throw away the remainder of the pack and begin a fresh pack the next day when you are a Day 1 starter. If you're a Sunday-based starter, you should continue taking a dose every day up until Sunday. On Sunday, toss away the remainder of the pack and start a fresh pack for the day.If you do not take three active pills in a row during the weeks of 1–2 or 3, you should throw away the remainder of your pack and begin a fresh pack the next day if you're a day 1 starter. If you're a Sunday-based starter, you should continue taking a dose every day up until Sunday. When you are done, take away the remainder of the pack and start a fresh pack for the day.If you skip 2 or 3 pills per day, it is possible that you will not experience a period for the rest of the month. If you do not have two months consecutively, contact your doctor, as there is a possibility that you are pregnant.If you do not remember to take a reminder pill, discard it and continue to take one pill a day until your pack is full.

What happens if I overdose?

For medical emergencies, seek emergency attention or contact the Poison Help Line at 1-800-222-1222. The symptoms of an overdose can include nausea, vomiting, and vaginal bleeding.

Avoid this 

Don't smoke when using birth control medications, especially if you are over 35 years old.Birth control pills do make it impossible to stop your illness from spreading. Don't engage in sexual activity that is not protected or share toothbrushes and razors. Consult your physician on how to avoid HIV transmission during sexual contact.

Interaction with other drug

Discuss with your doctor all other medicines you take, including:

  • Phenylbutazone;
  • Griseofulvin;
  • Bosentan;
  • Rifampin;
  • St. John's wort;
  • Glecaprevir/pibrentasvir;
  • Anticonvulsants (antiepileptics) like phenobarbital, phenytoin and carbamazepine lamotrigine, oxcarbazepine felbamate, or topiramate.

This list isn't complete. Other drugs can also influence Enskyce, which includes medications that are prescribed and available over the counter, vitamins, and herbal products. The list of possible interactions with drugs is included here.



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