The Web Health


Endocet 5/325

Generic name: acetaminophen and oxycodone [a-SEET-a-MIN-oh-fen-and-OX-i-KOE-done]
Names of brands: Endocet 10/325, Endocet 2.5/325, Endocet 5/325, Endocet 7.5/325, Nalocet,… list the 8 brands.
Drug class: narcotic analgesic combinations

What is Endocet 5/325?

Endocet 5/325 is a combination medicine used to relieve moderate to severe pain. Endocet 5/325 contains an opioid medicine and may be habit-forming. Endocet 5/325 may also be used for purposes not listed in this medication guide.

Side effects of Endocet 5/325

Seek medical attention immediately. If you are experiencing symptoms or warning signs of an allergic reaction, such as an allergic reaction that causes hives, breathing problems, and swelling of your lips, face, and throat, Opioid medication can cause a slowing or stopping of breathing, and even death can occur. The person who cares for you should administer the drug naloxone or seek medical attention if you experience breath that is slow, with pauses for a long time or blue-colored lips, or if it is difficult to get back up.In some cases, acetaminophen could cause a serious skin reaction, which can cause death. This could occur regardless of whether you've previously used acetaminophen and did not experience any reaction. Stop using Endocet 5/325 and consult your physician immediately when you notice the appearance of a skin rash or redness that causes blisters as well as peeling.Endocet 5/325 may cause serious side effects. Contact your physician immediately. If you suffer from:

  • Loud breathing, sighing, and breathing shallowly that stops;
  • A feeling of lightheadedness, as if you're about to pass out.
  • Fatigue, weakness, fever, unusual bleeding, or bruising;
  • Disorientation, strange thoughts, or behavior
  • Urinary problems;
  • Liver disorders: nausea and stomach pains in the upper region; fatigue; lack of appetite black stools, dark urine, and jaundice (yellowing of the eyes or skin);
  • Low levels of cortisol, nausea nausea, vomiting, nausea, vomiting, dizziness, fatigue that is worsening, or weakness
  • Serotonin levels are high within the body, causing anxiety and hallucinations. Fever, sweating, shaking, fast heart rate muscles stiffness, loss of coordination, twitching nausea, vomiting vomiting, diarrhea.

The presence of serious breathing issues is more common in older adults as well as in those who are weak or suffer from the syndrome of wasting and chronic breathing problems.

Common adverse reactions include:

  • Nausea, dizziness, and fatigue;
  • Feelings of extreme sadness or joy;
  • Nausea, vomiting, and stomach pain;
  • Constipation

This is not a comprehensive list of possible side effects, and other side effects could occur. Contact your doctor for advice regarding medical effects. You can report any symptoms to the FDA at 1-800-FDA-1088.


A MISUSE OF OPIOID MEDICINE could lead to addiction, overdose, or even death. Keep the medication in a location where other people are unable to access it.

Opioid medicine taken during pregnancy can result in life-threatening withdrawal symptoms for the baby.Side effects that are fatal can occur when you mix opioids in conjunction with alcohol or other substances that cause drowsiness or impede the rate of breathing.Take a break from this medication and contact your doctor immediately if you notice the appearance of a rash or redness on your skin that gets worse and leads to peeling and blisters.

Before you take this drug

You shouldn't make use of Endocet 5/325. if allergic to acetaminophen and Oxcodone or suffer from:

  • Extremely severe asthma or breathing issues or
  • An obstruction in the stomach or intestines.

Speak to your doctor if you have ever suffered from:

  • Breathing issues, sleep apnea;
  • The liver condition;
  • A dependency on alcohol or drugs;
  • Kidney disease;
  • A head injury or seizures;
  • Urination issues
  • Troubles that concern your pancreas, thyroid, or gallbladder.

If you are taking opioid medication while expecting, your child could develop a dependence on the medication. This can cause severe withdrawal symptoms for the newborn after it's born. Babies born dependent on opioids may need medical treatment for several weeks.

Consult a physician before taking opioids if you are nursing. Tell your doctor in case you notice a sudden increase in sleepiness or a slow breathing rate during the breastfeeding baby's

How to take Endocet 5/325?

Follow the directions on the prescription label. Don't take this medication in greater quantities or for longer than the time prescribed. An overdose can damage your liver or cause death. Inform your doctor if you notice an increase in your desire to take a larger dose of this medication.Do not share your opioid medication with a person, particularly one who has a history of substance abuse or addiction. A misusing of the medicine can result in addiction, overdosing, or death. Keep the medication at a distance from where others can't access it. Giving away or selling opioids is a violation of the law.Make sure to measure the liquid medicine with care. Make use of the syringe for dosing or a dose-measuring device (not an ordinary spoon).If you require surgical intervention or tests for medical reasons, notify your doctor prior to the time that you're taking this medication.It is not recommended to stop taking this medicine abruptly. Follow the instructions of your physician about increasing your dosage.

Place it in a cool, dry place far from heat and moisture. Make a note of the medicine you have purchased. It is important to be aware that you are using the medicine improperly and without a prescription.Don't keep any empty bottles of opioids. One dose could cause death for someone who is using the medicine in error or unintentionally. Ask your pharmacist where you can find a drug recycling program for takeback. If there isn't a taking-back system, then flush any unneeded medicine into the toilet.

What happens if I miss the dose?

Because Endocet 5/325 is prescribed for pain, you're less likely to skip a dose. Avoid any dose missed when it's time to take the next dose. Do not take two doses in one go.

What happens if I overdose?

Get medical attention immediately, make a call to emergency medical attention, or call the Poison Help Line at 1-800-222-1222. A high dose of this medication could cause death, especially in the case of a child or another person who is taking the medication without a prescription. Overdose symptoms may include vomiting, nausea, sweating, extreme dizziness, aplenty of pupils, and slow breathing. It could also mean not breathing.A doctor may suggest getting Naloxone (a medication that reverses an overdose of opioids) and carrying it around throughout the day. The person who is caring for you may give you naloxone when you cease breathing or aren't awake. The caregiver should still seek emergency medical assistance and could be required to perform CPR (cardiopulmonary resuscitation) on you as they wait for assistance to arrive.You can purchase naloxone at the local pharmacy or health department. It is important that everyone who cares for you understands where you store naloxone and how to utilize it.

What should be avoided?

Avoid operating machinery or driving until you understand how Endocet 5/325 can affect your health. Drowsiness or dizziness can lead to accidents, falls, or serious injuries.Don't drink or consume alcohol. Dangerous side effects or even death may occur.Consult a physician or pharmacist prior to taking any other medication that could contain acetaminophen (sometimes called APAP). Combining certain medicines could result in a deadly overdose.

Interaction with other drug

There is a possibility of breathing issues or withdrawal symptoms if you begin or stop taking other medications. Inform your doctor if you are also taking any antibiotic or antifungal medication. blood pressure or heart medicine, medication for seizures, or medication for treating HIV, as well as Hepatitis C.Opioid medications can interact with various other medications, causing deadly side effects or even death. Be sure your doctor is aware if you take:

  • Cold or allergy medications asthma, bronchodilator COPD medication, or diuretic ("water pill");
  • Medicines to treat motion sickness and irritable bowel syndrome medications for motion sickness, irritable bowel syndrome, or an overactive bladder;
  • Other opioids, such as pain medication and prescribed cough medicine;
  • A sedative such as Valium, diazepam, alprazolam, lorazepam, Xanax, Klonopin, Versed, and more
  • Medications that induce sleep or cause breathing to slow down—a sleeping pill, a muscle relaxer, or medications to treat mental illness
  • Serotonin-related drugs can alter the levels within your body, such as a stimulant or medication to treat depression, Parkinson's disease, migraine headaches, severe infections, sickness, and nausea.

This list isn't complete. Other drugs can interact with Endocet 5/325, such as prescription and over-the-counter medicines, vitamins, and herbal products. Not all interactions are included in this list.



Prescription only

Pregnancy & Lactation

CSA Schedule*
Related Drugs
Related Stories


NDC 60951-712-70, Endocet, 10 mg / 325 mg, side 1 is E 712,