What is Elelyso?
Elelyso is a synthetic form of an enzyme that occurs naturally in our bodies. It's utilized as an alternative to enzymes for adults and children who are aged 4 or older with Gaucher's disease type I.Gaucher disease is an inherited illness that causes the body to lack the enzyme that is needed for breaking down specific fat substances (lipids). Lipids build up within the body, leading to symptoms like bleeding or bruising, as well as anemia, weakness or joint pain, an enlarged liver or spleen, or weak bones that can easily break.Elelyso could improve the health of the spleen, liver, bones, and blood cells in people suffering from Gaucher's disease type 1. But Elelyso does not provide a cure for this disease.
Side effects of Elelyso
Take immediate medical attention. If you notice any indications of an allergic reaction or aversion to the Elelyso, such as difficulty breathing, hives, or swelling of your lips, face, and tongue,
A few people who received an Elelyso injection have experienced a reaction after the medication was administered, or as long as 3 hours after. Contact your doctor immediately if you experience:
- Feeling dizzy or like you're about to pass out
- Chest tightness and wheezing
- Facial swelling;
- Acute throat irritation, cough;
- Flushing (the warmth of redness or a tingly feeling);
- Nausea, vomiting,
- Itching, or itching,
Common Elelyso side effects can include:
- Headache;
- Itching, rash, or tingling feeling
- Tiredness or dizziness;
- Nausea, stomach pain, vomiting,
- Back pain, joint pain, or pain in your arms or legs.
This is not a comprehensive list of possible side effects, and other effects may also be present. Consult your physician for advice regarding medical adverse effects.Report any adverse reactions directly to the FDA at 1-800-FDA-1088.
Warnings
Certain people who have received an Elelyso injection have experienced a reaction following the time the medicine was administered, or even 3 hours after. Contact your doctor immediately in the event of an abrupt headache, dizziness, tingling in the chest, wheezing, nausea, or a rash on your skin that is red.Elelyso isn't a cure for Gaucher disease.
Before you take this drug
It is not recommended to use Elelyso if you are sensitive to taliglucerase alfa.Inform your doctor if you are expecting. It isn't known if the taliglucerase alfa drug can affect a baby who is not yet born. Untreated or uncontrolled Type I Gaucher disease during pregnancy could result in new or more severe symptoms for the mother or problems for the infant, such as bleeding or growth issues. The advantages of treating your illness could outweigh the risks for the baby.It is not recommended to breastfeed while taking Elelyso. Consult your physician about any potential risks.
Similar or related drugs
Cerezyme, Cerdelga, Eligibility, and Migration
How to take Elelyso?
Elelyso is injectable into a vein via an IV. Your healthcare professional will provide the injection.There are additional medications to help you avoid any allergic reactions. Continue to take these medications for the time your physician prescribes.There are other medications to avoid certain adverse effects associated with Elelyso.Elelyso is usually prescribed every two weeks. Follow the instructions of your doctor for dosage extremely carefully.Your doctor may alter your dosage to ensure that you get the most effective outcomes.Taliglucerase dosages for alfa are dependent on weight (especially in teenagers and children). Your dose requirements could change if you gain or lose weight.
Details on dosage
Usual Adult Dosage of Elelyso for Gaucher Disease:
Patients with no treatment 60 units/kg by IV infusion (administered in 60–120 minutes) every two weeks
Patients who are switching to imiglucerase
Patients who are currently treated with imiglucerase in the treatment of Type 1 Gaucher disease may be switched over to this drug.
Patients who have previously received an imiglucerase dose that is stable should start this medication at the same dose as they switch from imiglucerase to taliglucerase Alfa.
Dose adjustments are possible in accordance with the achievement and maintenance of each patient's therapeutic objectives.
A clinical study examined doses that ranged from 9.5 to 60 units/kg each week.
Use: To provide long-term, ongoing enzyme replacement therapy (ERT) for patients with a confirmed diagnosis of Gaucher disease type 1.
Usual Pediatric Dose of Elelyso for Gaucher Disease:
Ages 4 and over:
Patients who are not undergoing therapy: 60 units/kg by IV infusion (administered in between 60 and 120 minutes) every two weeks
Patients who are switching to imiglucerase
Patients who are currently treated with imiglucerase to treat type 1 Gaucher disease could be switched over to this drug.
Patients who previously had an indefinite dose of imiglucerase must begin the drug at the same dose as they change from imiglucerase to taliglucerase Alfa.
Dose adjustments are possible in accordance with the achievement and maintenance of therapeutic goals for each patient.
A study in clinical research evaluated doses that ranged between 9.5 and 60 units/kg once a week.
Use: As a long-term therapy for patients who have a confirmed diagnosis of Gaucher disease type 1.
What happens if I miss the dose?
Contact your doctor for advice. If you do not make an appointment to receive the Elelyso injection,
What happens if I overdose?
Get medical attention in an emergency or contact the poison help line at 1-800-222-1222.
What should be avoided?
Follow the doctor's advice regarding any limitations on foods, drinks, or activities.
Interaction with other drug
Other medications can be incompatible with taliglucerase alfa, such as prescription and non-prescription medicines as well as vitamins and herbal products. Inform your health professionals about any medication you are taking currently and all medicines that you decide to stop or begin taking.
